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971.
杨旭 《湖南城市学院学报(自然科学版)》2013,(3):10-16
桩周摩阻力、桩底反力与位移和土质有关.通过桩的静栽试验和对桩周摩阻力,桩底反力测试,并对试验数据进行分析,获得了在复杂地质条件下,基桩的荷载传递特性,桩土作用特点,桩周摩阻力及桩底反力发挥特性.在此基础上评估桩的承栽能力,可作为在复杂地质条件下进行桩基工程设计和施工的参考. 相似文献
972.
973.
法学的职业性特征本身决定了法律实践的重要性。而诊所式法律教育就是一种行之有效的实践性教学方法。但是,在教学实践中,诊所式法律教育却面临诸多困境。本文通过对法律诊所教育所面临困境的分析,进一步探讨解决的对策。 相似文献
974.
通过引入牵连动量和相对动量等物理量,用图示分析法研究了弹性碰撞.研究结果表明,该方法可以形象而直观地描述弹性碰撞的过程和结果,对弹性碰撞的理论研究和实际应用都有重要的意义. 相似文献
975.
Epistasis between cytoplasmic and nuclear genes is the primary genetic component of complex quantitative traits.Genetic dissection of cytonuclear epistasis is fundamentally important to understand the genetic architecture of complex traits.In this study,a two-dimensional genome scan strategy was employed to evaluate the contribution of cytoplasm,quantitative trait loci (QTL),QTL×QTL interactions and QTL×QTL×cytoplasm interactions to the phenotypic variation.The p-value and parameter value for each genetic effect were calculated by multiple regression analysis.A stepwise approach was suggested to build confidence in candidate QTL on the basis of q-value estimation,false discovery rate calculation and Bonferroni adjustment.A fine-scale grid scan strategy was proposed for further analysis of peaks of interest.Plant height in maize was used as an example to illustrate the efficiency of the two-dimensional genome scan strategy. 相似文献
976.
Hydrogels resulting from the self-assembly of small peptides are smart nanobiomaterials as their nanostructuring can be readily tuned by environmental stimuli such as pH,ionic strength and temperature,thereby favoring their practical applications.This work reports experimental observations of formation of peptide hydrogels in response to the redox environment.Ac-I 3 K-NH 2 is a short peptide amphiphile that readily self-assembles into long nanofibers and its gel formation occurs at concentrations of about 10 mmol/L.Introduction of a Cys residue into the hydrophilic region leads to a new molecule,Ac-I 3 CGK-NH 2,that enables the formation of disulfide bonds between self-assembled nanofibers,thus favoring cross-linking and promoting hydrogel formation.Under oxidative environment,Ac-I 3 CGK-NH 2 formed hydrogels at much lower concentrations(even at 0.5 mmol/L).Furthermore,the strength of the hydrogels could be easily tuned by switching between oxidative and reductive conditions and time.However,AFM,TEM,and CD measurements revealed little morphological and structural changes at molecular and nano dimensions,showing no apparent influence arising from the disulfide bond formation. 相似文献
977.
荧光标记的叶酸修饰壳聚糖纳米载体研制 总被引:2,自引:0,他引:2
制备荧光标记的叶酸偶联壳聚糖纳米粒,为抗肿瘤药物给药系统提供载体材料。通过叶酸活性酯与壳聚糖上的氨基反应,使叶酸与壳聚糖偶联。将异硫氰基荧光素与叶酸偶联壳聚糖进行化学嫁接,以离子交联法制成具有荧光的叶酸偶联壳聚糖纳米粒,并与肝癌HepG2细胞进行体外细胞实验。实验结果表明:叶酸活性酯用量和反应温度及试剂滴加速度是影响偶联比的主要因素;在叶酸活性酯与壳聚糖用量质量比为1:1,反应温度为30℃,滴加速度为2mL/min,反应时间为12h的条件下可得到偶联稳定的叶酸偶联壳聚糖;所制得的纳米粒粒径为290nm,形态规则,细胞荧光效果明显;此方法能用于制备荧光标记的叶酸修饰壳聚糖纳米粒载体。 相似文献
978.
从清末民国的免费师范生制度的具体内容,尤其是有关服务期问题的相关政策,以及这一制度施行的实际效果和存在的问题,有助于更好的完善当今的免费师范教育的角度,主要通过考察清末民国时期的免费师范生制度及存在问题,探讨其为当今免费师范教育留下的极具借鉴意义的经验教训,从而为当今免费师范生制度的改进提出一些建议。 相似文献
979.
Surface pollen assemblages of human-disturbed vegetation and their relationship with vegetation and climate in Northeast China 总被引:1,自引:0,他引:1
ManYue Li YueCong Li QingHai Xu RuiMing Pang Wei Ding ShengRui Zhang ZhiGuo He 《科学通报(英文版)》2012,57(5):535-547
Pollen assemblages of 53 surface pollen samples from farmlands and wastelands in Northeast China were analyzed. Tree pollen percentages were usually higher than 30%, with Pinus (26.9%), Quercus (0.9%), Betula (0.9%) and Populus (0.7%) as the major types, and herb pollen percentages were usually higher than 50%, with weedy Poaceae (8.7%), Chenopodiaceae (7.1%), Artemisia (1.9%) and Compositae (3.5%) as the major taxa. Thus, the pollen assemblages were consistent with the regional vegetation compositions. However, there were differences in pollen assemblages among regions, especially among different geomorphological units. For example, in the mountains, there were more types of tree pollen and higher total percentages (average 42%) than in other areas, while cereal pollen percentages were lowest (11.2%). In the hills and high plains, herbs made up more than 60% of the pollens, with cereals (average 53.6%) the dominant type. In the low plains, pollen types were similar to those in the hills and high plains, but total pollen concentrations and the proportion of Concentricystes were much higher, while cereal pollen percentages were slightly lower (average 41.6%). Pollen assemblages in different land use types also differed. For example, in farmland, cereal pollen percentages were more than 40% and Chenopodiaceae was usually less than 2.5%, while in wasteland, weedy Poaceae was usually less than 10% and Chenopodiaceae was usually higher than 25%. Total pollen concentrations in farmland (average 3909 grains/g) were much lower than in wasteland (average 15074 grains/g). Redundancy analysis revealed that pollen assemblages were significantly negatively correlated with mean annual temperature (-0.73) and July mean temperature (-0.81) and significantly positively correlated with mean annual precipitation (0.48), indicating that pollen assemblages in the artificial or human-disturbed vegetation reflect regional climate well. Comparison of pollen assemblages in different areas of northern China showed that pollen concentrations reflect the intensities of human impact to some degree. For example, pollen concentrations decrease as human impacts increase in intensity. The cereal pollen proportions in farmland differed by area. In Northeast China, cereal pollen proportions were distinctly higher than in most other areas of northern China, suggesting differences in planting habits and climate. 相似文献
980.