针刺麻醉与镇痛泵在肩关节术后镇痛领域中的应用及评价

以行肩关节手术的患者作为研究对象,比较和评价了针刺麻醉与肩峰下自控型镇痛泵对术后镇痛的疗效与安全性,指标包括疼痛视觉模拟评分（VAS）、肩关节活动度（ROM）、Lovett肌力分级等,结果显示镇痛泵组的胃肠道不良反应发生率（7/64）、基础病复发率（4/64）,及总体不良反应发生率（16/64）均显著高于针刺组（0/70）(0/70)(4/70),在轻度疼痛者中,2组的VAS未见差异,但针刺组的ROM更大,在中、重度疼痛者中,镇痛泵组的VAS低于针刺组,但2组的ROM及肩关节肌力未见差异,说明针刺麻醉的安全性极佳,可促进术后康复,适用于轻度疼痛者及合并相关内科基础病的中、重度疼痛者。     

人工干预压采条件下东风湖泉域地下水环境响应研究

为掌握我国北方典型岩溶泉域在人工干预条件下地下水的动态响应规律,以涉县东风湖泉域为研究对象,结合区内地质、水文地质、2011-2021年地下水位动态监测和地下水压采资料,在分析该地区地下水动态变化特征的基础上,运用GMS软件构建了在人工压采干预作用下的地下水流数值模拟模型,对地下水位变化趋势进行了预测。结果表明：①研究区地下水动态变化明显,具有周期性、滞后性,具体表现为4个变化阶段;②研究区内岩溶地下水整体呈现回升的状态,但是空间分布特征不同,上升区主要分布于下游地区;;③地下水类型为降水入渗-开采型,低水位期基本在5-6月,高水位期在1-2月;④在干预条件下,区内地下水位有着不同程度的回升,南部(下游)浅层水位响应特征值超过15m,中游地下水位响应特征值达到了5-10m,北部(上游)地下水位响应特征值为3-5m;上游和中游地下水位影响整体小于下游,下游水位响应尤为突出。该研究对于泉域内泉的保护以及地下水开发利用和保护具有重要的理论和实际意义。     

Disruption of mitochondrial function as the basis of the trypanocidal effect of trifluoperazine onTrypanosoma cruzi

Summary The tricyclic anti-calmodulin drug trifluoperazine (TFP) inhibited growth and motility of epimastigotes ofTrypanosoma cruzi, at concentrations lower than 100 M, and motility and infectivity of the bloodstream trypomastigote form at 200 M. Electron microscopy of TFP-treated epimastigotes showed that the major effect was at the mitochondrial level, with gross swelling and disorganization. The oligomycin-sensitive, mitochondrial ATPase was completely inhibited by 20 M TFP, and the same drug concentration caused a 60% decrease in intracellular ATP content. The results suggest that the trypanocidal effect of TFP may be related more to mitochondrial damage than to the well-known anticalmodulin effect of the drug.     

Evolutionary distinctiveness of the endangered Kemp's ridley sea turtle

The endangered Kemp's ridley sea turtle (Lepidochelys kempi) nests almost exclusively at a single locality in the western Gulf of Mexico, whereas the olive ridley (L. olivacea) nests globally in warm oceans. Morphological similarities between kempi and olivacea, and a geographical distribution that "...makes no sense at all under modern conditions of climate and geography", raise questions about the degree of evolutionary divergence between these taxa. Analysis of mitochondrial (mt) DNA restriction sites shows that Kemp's ridley is distinct from the olive ridley in matriarchal phylogeny, and that the two are sister taxa with respect to other marine turtles. Separation of olive and the Kemp's ridley lineages may date to formation of the Isthmus of Panama, whereas the global spread of the olive ridley lineage occurred recently. In contrast to recent examples in which molecular genetic assessments challenged systematic assignments underlying conservation programmes, our mtDNA data corroborate the taxonomy of an endangered form.     

材料断口中的分形(英文)

分形几何(Fractal geometry)是近年来出现的一门应用数学分支。本文简要介绍了分形在材料断裂表面分析中的应用概况,并叙述了本文作者关于“延性断裂韧性与断裂表面的分形”研究工作。如果继续深入研究,将可从材料破坏的断口上直接分析并推知其断裂特性,从而为材料的失效分析提供一种简便而实用的新方法。