DanHong Injection inhibits the development of primary abdominal aortic aneurysms in apoE knockout mice

Clinical observations indicate that DanHong Injection （DHI） can increase blood flow and reduce various syndromes in patients with cardiovascular disease. How- ever, it still needs to define the function of DHI and the involved mechanisms in details, such as the protective effect on the development of primary abdominal aortic aneurysms （AAAs）. In this study, we determined whether DHI is able to inhibit AAA in apoE knockout （apoE-/-） mice. Thirty apoE-/- male mice on high-fat diet （0.5 % cholesterol, 21% fat） were randomly divided into two groups and received i.p. injection of saline （100 μL/day） and DHI （100 μL/day）, respectively, for 16 weeks. At the end of experiment, we determined the development of atherosclerosis in en face aorta and aneurysms,pathological morphology of arterial wall, and serum lipid levels. We also determined the expression of monocyte chemoattractant protein-1 （MCP-1）, MMP-2, and MMP-9 mRNA in aortic wall using real-time RT-PCR. Our results indicated that high-fat diet induced the development of AAAs in apoE-/- mice, but the induction was totally blocked by DHI （P 〈 0.01）. The result of staining of abdominal aortic cross sections showed that DHI main- tained the collagen content in arterial wall, thereby pre- venting the animals from the development of AAA. Although DHI had little effect on serum total- and LDL- cholesterol levels, it reduced the expression of MCP-1, MMP-2, and MMP-9 mRNA in aortic wall （P 〈 0.01）. Taken together, our study suggests that DHI can inhibit the high-fat diet-induced AAA formation. The inhibitory effects may be related to the maintenance of the collagen content and inhibition of expression of AAA-related genes. Our study may suggest a new application of DHI in clinics.     

一种适用于牧区的新型太阳能系统

我国是世界上地质灾害最严重的国家之一,对人民群众的生命财产安全构成了极大的威胁.湖南省又是我国地质灾害较严重的省份之一,且水系发育,河湖地地质灾害较多.本文以澧县为例,介绍了河湖地区管涌、岸崩的发育特征、分布规律及形成因素等,并提出了相应的防治措施,最后对河湖地质灾害进行了易发性分区,取得了较好的实际效果.结果表明:文中提出的方法对河湖地区的地质灾害防治具有一定的实际指导意义.     

碱性与中基性粗集料影响混凝土抗冻性能对比

粗集料作为混凝土的重要组成材料,其品质直接关系到混凝土的各项性能.通过试验对比研究了碱性矿料石灰岩(ω(SiO_2)为1.01%)和中基性矿料玄武岩(ω(SiO_2)为53.5%)混凝土的抗冻性能,分析了两类试件的质量损失率和相对动弹性模量.结果表明:碱性矿料能够提高混凝土的抗冻性能,这对解决混凝土抗冻性能具有重要意义.     

霍林河水库渗漏探测试验研究

高密度电法是常用的物探方法,在水库大坝探测方面也经常用到.文中介绍了高密度电法的原理和反演分析方法,采用高密度电法对霍林河水库大坝渗漏情况进行了探测试验,采用"单极-单极"阵列方式分别对大坝的4个断面进行了渗漏探测试验,并结合实测资料分析大坝渗漏原因.试验结果表明:高密度电法有效地探测了霍林河水库大坝渗漏情况,检验了防渗处理的效果,为大坝防渗加固提供了依据,也进一步验证了高密度电法在水库渗漏探测中具有较好的效果.     

球笼式万向联轴器试验设计与性能分析

实际使用过程中发现：转速、摆角、扭矩是导致球笼式同步万向联轴器本体发热量过大、寿命降低的主要原因.本文采用正交试验法对球笼式同步万向联轴器的性能进行测试,利用极差分析法对正交试验结果进行分析.结果表明对球笼本体发热量大小的影响程度依次是转速、摆角、扭矩,最后对球笼式万向联轴器的设计提出了建议.     

基于突变理论的员工主动离职行为定性模拟——以中国经济转型期的“离职潮”为例

刘易斯拐点的到来导致中国劳动力成本大幅上升,这使得如何避免员工主动离职成为保证企业人力资源稳定的核心问题。针对离职行为这一复杂系统,从实证研究与突变理论相结合的全新视角,构建了员工主动离职的突变概念模型。在此基础上引入定性模拟算法,提出了突变函数在离职行为研究中的参数估计方法,并通过长三角地区某企业的实际案例验证了该方法的合理性及鲁棒性。最后,根据经济转型期的"离职潮",对员工主动离职的定性-定量混合突变模型进行虚拟实验分析。实验结果从精确测定员工离职的预警区、临界区和突变区及复杂经济环境与员工离职的关系,以及企业微观层面和政府宏观层面的控制策略等方面,为员工主动离职问题提供了决策支持。     

浅谈天车“抬”吊巨大设备吊装点的精确计算

为保证设备的安全吊装,分析建立了一个数学模型,计算确定吊装点的精准设置位置,为吊装方案的细化编制和起重吊装的实际操作提供数据上的依据和支持,精确吊装方法和吊装点对制定吊装方案具有决定意义。     

High-performance flexural fatigue of carbon nanotube yarns

Carbon nanotube yarns （CNTY） possess good specific strength and specific conductivity. As such, their potential for commercial applications is significant. Fatigue performance is a significant consideration in yarn/wire applications. In this study, the flexural fatigue performance of CNTY spun from super-aligned carbon nanotube arrays was investigated using a reversed bending test. The results showed that CNTY exhibited excellent resistance to pure flexural fatigue, significantly outperforming stainless steel wire; CNTY failed where a combination of flexural fatigue and tension-tension fatigue had special hollow fracture morphology, and CNTY resistance remained fundamentally unchanged in the combination fatigue process.     

西藏农村人力资本投资困境分析

农村人口综合素质整体不高,日益成为西藏农村反贫困和可持续发展的重要制约因素之一,加大人力资本投资日益迫切.文章提出没有基于本地化的农村办学思路,师资队伍整体落后与教育质量不高长期并存,教育投资观念偏差根深蒂固,基层卫生服务能力薄弱及健康知识普及严重不足等是当前西藏农村人力资本投资存在的诸多困境,并指出尽快优化教育发展结构、突出师资队伍建设、加强成人培训力度、关注妇女儿童健康是提高农村人口发展能力的重要途径.