生物可降解哑铃状高分子共聚物替莫唑胺载药微球的制备与表征

以生物可降解的哑铃状高分子共聚物材料作为药物载体,饱和替莫唑胺水溶液为选择性溶剂,采用透析法制备了替莫唑胺载药微球。通过动态光散射仪、扫描电镜、紫外分光光度计对替莫唑胺载药微球的粒径分布、表面形貌、载药量及释放行为进行了研究。结果表明:微球载药后其平均粒径不超过800nm,载药量可以达到39.9%;体外释放时间可达900h以上,且可用n级动力学速度方程较为真实地反映其释放行为。细胞实验证明了替莫唑胺载药微球对人源性SHG-44细胞的抑制效果优于替莫唑胺纯药粉末。     

准噶尔盆地石炭系火山岩优质储层特征及主控因素

针对准噶尔盆地石炭系火山岩储层非均质性强、优质储层特征及控储机理认识不清的问题,选取盆地内在石炭系火山岩钻井中,试油结果显示日产油达到10 t/d或日产气达到5×104m3/d以上的135口工业油气井作为研究对象,通过对录井、测井、试油资料的系统分析,利用岩芯观察、薄片鉴定、测井响应、物性实验数据等对石炭系火山岩优质储层进行综合研究.结果表明:石炭系优质火山岩储层岩性变化较大,主要以溢流相的基性玄武岩、中性安山岩和爆发相的凝灰岩、火山角砾岩为主;储集空间主要为次生溶蚀空隙和裂缝,原生孔隙较少.在此基础上提出了准噶尔盆地石炭系火山岩优质储层形成的"三元控储"模式:岩性-岩相控制了原生空隙的发育和储集体的规模、岩石-流体相互作用控制了次生孔隙的形成与演化、构造-应力耦合控制了储层的有效性.     

基于成本最小的公交人员排班优化模型

为了优化公交人员排班问题,提高公交公司的运营效率和资源利用率,以车辆行车计划为基础、公交公司运营成本最小为目标,构建了公交人员排班问题理论模型,并利用遗传算法和LINGO优化软件分别进行实例求解。算例分析表明,该模型具有可行性和合理性。     

Effects of baria on propane oxidation activity of Pd/Al2O3 catalyst: Pd–BaO interactio n and reaction routes

The BaO-modified Pd/Al2O3exhibits much better catalytic activity than Pd/Al2O3for C3H8 oxidation both before and after the hydrothermal aging treatment. Further studies ascribe its good activity to the influence of BaO species on the physicochemical characteristics of the catalyst and the reaction routes. Firstly, the BaO species inhibits the phase transformation of alumina, resulting in higher surface area of the catalysts and hereby a better dispersion of Pd. Secondly, the basic nature and electron-withdrawing effect of barium oxide maintain palladium at high oxidation state, which leads to a higher PdO content on surface of the BaO-modified catalyst. Finally, the formation/decomposition of carbonate/bicarbonate species can be promoted by the addition of BaO, which provide extra reaction routes and are important for the deep oxidation of C3H8.     

Φ6250土压平衡盾构机出渣能力设计计算

简要介绍了土压平衡盾构的排渣系统,指出了保持其土仓压力平衡的重要性。并以太重Φ6250土压平衡盾构机为考察依据,对该盾构机的螺旋输送机的排渣能力和皮带运输机的运输能力进行了设计核算。     

Temporal dynamics in social trust prediction

Inferring unknown social trust relations attracts increasing attention in recent years. However, social trust, as a social concept, is intrinsically dynamic, and exploiting temporal dynamics provides challenges and opportunities for social trust prediction. In this paper, we investigate social trust prediction by exploiting temporal dynamics. In particular, we model the dynamics of user preferences in two principled ways. The first one focuses on temporal weight; the second one targets temporal smoothness. By incorporating these two types of temporal dynamics into traditional matrix factorization based social trust prediction model, two extended social trust prediction models are proposed and the cor- responding algorithms to solve the models are designed too. We conduct experiments on a real-world dataset and the results dem- onstrate the effectiveness of our proposed new models. Further experiments are also conducted to understand the importance of temporal dynamics in social trust prediction.     

An Improved ID-Based Group Key Agreement Protocol

ID-based constant-round group key agreement protocols are efficient in both computation and communication, but previous protocols did not provide valid message authentication. An improvement based on attack analysis is proposed in this paper. The improved method takes full advantage of the data transmitted at various stages of the protocol. By guaranteeing the freshness of authentication messages, the authenticity of the generator of authentication messages, and the completeness of the authenticator, the improved protocol can resist various passive and active attacks. The forward secrecy of the improved protocol is proved under a Katz-Yung （KY） model. Compared with existing methods, the improved protocol is more effective and applicable.     

典型屋顶太阳能光伏板风压实测研究

对一栋多功能低层建筑平屋顶上的太阳能光伏板进行风压实测,根据风压时程特性选择适当的概率密度函数对各测点的风压系数进行非线性回归分析.运用6种概率密度函数对各测点的均值和极值(正极大值和负极小值)风压系数时程以及面积平均后的极值风压系数时程进行数值拟合,比较不同概率分布的拟合效果.回归分析结果表明:均值风压系数的概率分布近似无偏分布,t分布的拟合效果最好,其次是Logistic分布、正态分布、极值I型分布;负压极小值和正压极大值风压系数的概率分布分别为左偏分布和右偏分布,极值I型分布的拟合效果最好,其次是Lognormal分布和Gamma分布,而正态分布的拟合效果最差;最不利风压系数由极值负风压控制,即光伏板的风力由吸力主导;经面积平均后的最不利风压系数建议取值-2.3.     

混响室条件下辐射敏感度表征方法研究

为确定混响室条件下辐射敏感度的表征方法,分别对混响室步进模式和连续模式下的电磁环境特征进行分析,得出可能的几种表征方法. 再将某型电子设备分别在两种工作模式下进行电磁辐射敏感度测试,利用几种可能的表征方法分别得出其测试结果,并对各个表征方法进行分析. 基于贝塞尔公式对各个可能的表征方法进行重复性及不确定检测. 结果表明,为了获得良好的测试可重复性及不同模式的测试结果相关性,混响室步进模式时,可采用多个步进位置的平均值作为辐射敏感度的测试结果;混响室工作于连续模式时,应当选择适当的统计平均时间参数对测试结果进行表征.      

GaAs/Al_xGa_(1-x)As非对称耦合双量子阱中的激子态

考虑三元混晶效应,采用变分法计算GaAs/AlxGa1-xAs非对称耦合双量子阱中激子的结合能及其尺寸和压力效应.结果表明:由于双阱的耦合作用,激子结合能表现出与对称情形显著不同的性质,随着阱宽的非对称变化,激子类型可在直接型和间接型之间相互转化.在中间垒厚取较小的固定值时,结合能随左阱宽的增加先减小到一极小值,后增大再减小;随着中间垒厚的增加,结合能最初展现微弱震荡变化,然后突然减小.结合能随Al组分和压力影响均受双阱的耦合和对称性影响较大.