某通用小型汽油机箱体有限元分析及结构优化

该文运用有限元法对某通用小型汽油机箱体进行了结构强度与刚度分析，结果表明右箱体主轴承位置最大变形量过大，刚度较差。为此对右箱体主轴承区域进行拓扑优化。优化方式为：增加右箱体主轴承处加强筋数量、增加壁面厚度以及在壁面上添加加强条。通过计算表明，该优化方式能使箱体的最大应力与应变大大下降，使其强度刚度有了较大提升，箱体的结构更趋合理。     

基于ARM9的嵌入式图像采集与显示系统设计

以嵌入式ARM9处理器S3C2440作为控制芯片,通过USB摄像头对图像进行采集,利用Video4Linux的编程接口编写QT图像显示程序,通过视频服务器MJPG-streamer对网络进行访问,实现了图像的采集和实时显示.所设计的系统实时性好、分辨率高、成本低、易扩展且升级快,可用于远程监控等领域.     

Aptamer and its applications in neurodegenerative diseases

Aptamers are small single-stranded DNA or RNA oligonucleotide fragments or small peptides, which can bind to targets by high affinity and specificity. Because aptamers are specific, non-immunogenic and non-toxic, they are ideal materials for clinical applications. Neurodegenerative disorders are ravaging the lives of patients. Even though the mechanism of these diseases is still elusive, they are mainly characterized by the accumulation of misfolded proteins in the central nervous system. So it is essential to develop potential measures to slow down or prevent the onset of these diseases. With the advancements of the technologies, aptamers have opened up new areas in this research field. Aptamers could bind with these related target proteins to interrupt their accumulation, subsequently blocking or preventing the process of neurodegenerative diseases. This review presents recent advances in the aptamer generation and its merits and limitations, with emphasis on its applications in neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, transmissible spongiform encephalopathy, Huntington’s disease and multiple sclerosis.     

An effective amperometric biosensor based on graphene modified gold nanowire arrays for glucose detection

A novel glucose biosensor based on graphene nanosheets （GNs） modified gold nanowire arrays （AuN- WAs） electrode was constructed. Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates. GNs were synthe- sized through a public route involving graphite oxidation, exfoliation, and chemical reduction. Field emission scan- ning electron microscope and high-resolution transmission electron microscope were employed to characterize the as- prepared AuNWAs and GNs. Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method. The cyclic voltam- metry results showed that the GNs-AuNWAs-based glu- cose biosensors have high catalysis activity to hydrogen peroxide （H2O2） than those modified with GNs or AuN- WAs only. Furthermore, amperometric response was employed to detect glucose concentration owing to its simplicity, high selectivity, and relative low cost. Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sen- sitivity of 40.25 μA cm^-2 （mmol/L）^-1, low detection limit of 0.02 mmol/L, and a linear range from 0.02 to 3 mmol/L.     

Mechanisms functional underlying the characteristics structural and of acupoints

Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow. Acupoints can respond to stimuli and reflect syndromes. Research on the essential morphology of acupoints has two key focuses： anatomical structure and physiological func- tion. The structure is the material and anatomical basis for the function, while the function is the manifes- tation of the structure. The two factors not only have profound significance for our understanding of the essence of acupoints, but also have great value for clinical acupuncture and moxibustion practice. Based on the structural and functional characteristics of meridians under different physiological and pathological con- ditions, this paper illustrates the essence of acupoints and explores the rules and biological basis of the acu- point functions induced by acupuncture and moxibustion.     

大黄酚脂质体包封率测定方法的研究

目的建立大黄酚脂质体包封率的测定方法。方法采用低速离心法分离载药脂质体与游离的药物,采用紫外分光光度法测定大黄酚的含量,计算出包封率。结果实验结果表明,当离心条件为1 500r/min、离心时间为120s时,可将载药脂质体与游离药物有效地分离,并测得3批大黄酚脂质体的包封率分别为82.29%,83.25%和83.06%,符合2010版《中华人民共和国药典》的规定。结论该方法简便快速,准确可靠,可用于测定大黄酚脂质体的包封率。     

基于SVD的通信信号背景下脉冲波形和初相估计

雷达侦察接收机往往侦察到的是通信和雷达脉冲的混合信号，如何从通信信号背景中有效提取出雷达脉冲波形，是现代雷达信号处理领域中的重要内容。针对这一问题，提出了一种基于奇异值分解的通信与雷达混合信号中脉冲波形估计算法。该算法通过对信号观测矩阵的奇异值分析和协方差矩阵的特征值分析，证明了观测矩阵的奇异值分解具有稳定性，并且奇异值分解能够最佳近似观测信号的线性特征，给出了一种利用左右奇异向量估计脉冲波形及其相对初相的方法。本文的算法适用于任意脉冲波形，并且能够在较低信噪比环境下估计脉冲信号波形和相对相位，仿真结果证明了算法的有效性。     

“全国文学创作”山西中心选址方案的合理性探讨

在分析"全国文学创作"山西中心项目建设的依据及必要性基础上,从选址方案的规划、交通、市政基础设施等方面,对选址方案的合理性进行了探讨。     

广东流动图书馆模式对广西壮族自治区图书馆流动服务的启示

探讨了目前广西壮族自治区图书馆汽车图书服务存在的问题和不足,参考并吸收广东流动图书馆模式的先进经验,提出了改进并完善汽车图书馆服务体系及管理制度的措施,探索出一套符合广西壮族自治区区域特点的流动图书馆服务模式。     

通识教育下的微积分教学探讨——引导学生从传统学习到自主学习

通识教育(General Education)是对本科人才培养模式的探索,是素质教育的延伸及发展.通识教育作为高等院校一项素质教育的重要改革举措,逐渐成为一种热潮,但其形式又不统一.在通识教育的潮流下如何进行微积分教学,值得商摧.