一种新型扭转金属阻尼器及其减震性能分析

为解决现有金属阻尼器应力分布不均匀的问题,设计了一种新型层间扭转型金属阻尼器,推导出初始刚度和屈服荷载表达式,并通过往复加载试验对其力学性能进行研究.根据阻尼器的试验过程建立有限元模型,分析其变形后的应力分布,对设有该扭转型耗能梁段与剪切型耗能梁段的Y形支撑结构进行了抗震性能研究.结果 表明:建立的扭转金属阻尼器力学模...     

基于LabVIEW的电梯钢丝绳状态监测多通道数据采集

针对电梯钢丝绳运行状态存在的在线监测困难、故障检测不准确的问题,搭建模拟电梯钢丝绳运行的实验台,通过设计励磁器、检测器结构,设计基于LabVIEW的电梯钢丝绳状态监测多通道数据采集系统。对钢丝绳断丝、磨损等常见故障信号进行多通道采集并实时显示波形图、存储数据以便进行进一步分析。试验表明,该系统可以多通道采集钢丝绳的漏磁信号,提高了信号的空间分辨率,能准确地检测不同程度的钢丝绳断丝磨损等故障信号,并将采集到的数据以TDMS文件的形式保存下来进行波形回放,进一步定量分析故障部位及程度。     

On-line spheroidization process of medium-carbon low-alloyed cold heading steel

Conventionally manufactured 35CrMo cold heading steel must undergo spheroidization annealing before the cold heading process. In this paper, different types of deformation processes with various controlled cooling periods were operated to achieve on-line spheroidal cementite using the Gleeble-3500 simulation technique. According to the measured dynamic ferrite transformation temperature (A_d3), the deformation could be divided into two types: low temperature deformation at 810 and 780℃; “deformation-induced ferrite transformation” (DIFT) deformation at 750 and 720℃. Compared with the low temperature deformation, the DIFT deformation followed by accelerated cooling to 680℃ is beneficial for the formation of spheroidal cementite. Samples subjected to both the low-temperature deformation and DIFT deformation can obtain granular bainite by accelerated cooling to 640℃; the latter may contribute to the formation of a fine dispersion of secondary constituents. Granular bainite can transform into globular pearlite rapidly during subcritical annealing, and the more the disperse phase, the more homogeneously distributed globular cementite can be obtained.     

基于SuperMap IS.NET5的大气环境质量评价系统

 以SuperMap 为技术平台,以SuperMap IS.NET5 为开发平台,以SQL Server 2005 为数据库平台,以面向对象程序设计语言C#为开发语言,以Microsoft VS.net 为开发环境,开发了基于SuperMap IS.NET5 的大气环境质量评价系统,应用该系统对大庆市大气环境质量进行评价。结果表明,该大气环境质量评价系统具有操作方便、实时、兼容性好、数据查询及统计分析等特点,评价出的大气环境质量级别准确、合理、客观,与实际情况相符合,在地图上直接输出结果,直观、实时、形象地提高了大气环境质量评价速度和评价效果。     

热疗的发展历程与展望

 热疗是一种历史悠久的疾病治疗方法,在中国和世界各地都有用热疗治愈疾病的历史记载.本文主要从技术、产品和临床3 个方面综合回顾了现代热疗的发展历程,分析了微波、射频、超声等热疗技术的进步和磁感应热疗等新型热疗技术的出现.分析表明,目前热疗已经发展到了一个新的高度,可以实现更高的治疗温度,温度控制更精确,副作用更小,疗效更好;在肿瘤治疗领域,热疗甚至有可能成为一种新的主流治疗手段,在一些常见的良性疾病治疗方面也将得到更广泛的应用.     

Preparation of Functional Polymeric Microspheres

1 Introduction Because of the wide applications in the area of biomedical and biotechnological fields, a great efforts have been done to fabricate different kinds of microspheres with tailored structural and surface properties over the last decade~([1]). Among them, stimuli responsive microspheres are microspheres that show ability to change their physical-chemical properties and colloidal properties in response to environmental stimuli such as changes of temperature, pH, chemicals, light, ele…     

Synthesis of two new thiazolidines and their hepatoprotective effects

Two new 2-substituted thiazolidine-4（R）-carboxylic acids （TCAs）, 2-glusosaminal-TCA （GIcNH2Cys） and 2-N-acetyl-glueosanlinal-TCA （GlcNAeCys）, were synthesized. Their protective effects against liver toxicity induced by acetaminophen （APAP） were investigated in a mice model. The resuits demonstrate that administration of TCAs （ i. p. , 800 mg/kg） 30 min after APAP challenge efficiently decrease ALF, AST, and LDH levels in liver. GlcNAcCys shows the best proteetive eftects, decreasing ALT, AST and LDH levels to 63%, 18.4% and 37% of the APAP group respectively. Comparison with the control showed that APAP greatly decreases total sulfhydlyl （T-SH） levels （43%）, non-protein hound sulfhydryl （NP-SH） levels （50%） and total antioxidative capabilities （57%） in the liver 24 hr after challenge. TCAs treatments 30min after APAP challenge significantly elevate sulfhydryl levels and total antioxidative capabilities. APAP administration also markedly （P 〈 0.05） increases liver lipid peroxidation to 1.65 and 1.17 times that of the control 4 hr and 24 hr after APAP administration respectively. TCAs treatments can inhibit lipid peroxidation as measured by decreased malondialdehyde （MDA） contents in liver. The histopathological results also further confirm the hepatoprotective effects of TCAs. In conclusion, our data show that TCAs, GleNAcCys particularly, have hepatoprotective anti antioxidant etfects.     

利用基质辅助激光解吸电离质谱成像技术研究斑马鱼响应富营养化污染水质内源性脂质分子变化

斑马鱼作为一种常见的模式物种,体内易富集水中污染物,常用于农药、有机物等污染水质监测与评估,但其响应富营养化水质污染的分子机制尚不明确.基质辅助激光解吸电离质谱成像(matrix assisted laser desorption ionization mass spec-trometry imaging,MALDI-MSI)能有效检测和反映分子空间分布及原位含量信息,已被广泛应用于动植物学、基础医学、药学、微生物等诸多研究领域.采用MALDI-MSI技术,针对富营养化污染水质环境下斑马鱼内源性脂质代谢分子开展原位分析表征;利用多元统计学方法和相关性分析整合数据;进一步挖掘有效关键信息,旨在从脂质分子层面上初步揭示斑马鱼响应富营养化污染水质的相关分子变化规律.研究结果显示:在m/z 500～1000的质量检测范围内,富营养化水质处理组和未处理组斑马鱼有超过50％原位检测的脂质分子存在明显表达与空间分布差异.主成分分析(principal component analysis,PCA)、偏最小二乘法判别分析(partial least squares discriminant analysis,PLS-DA)及皮尔逊相关聚类热图分析(pearson correlation cluster heatmap analysis)进一步证实了上述差异结果,且统计发现磷脂分子的表达受富营养化污染水质的干扰尤为突出,主要包括PC(32:0)、PC(34:1)、PC(34:2)、PC(36:0)、PC(38:6)、PC(40:6)、PE(36:8)、PE(36:0)、PE(38:0)、PE(40:9)共10种脂质分子.研究结果为进一步深度探究斑马鱼响应富营养化污染水质体内脂质代谢分子机制奠定了一定的实验基础,也证实了MALDI-MSI作为一种新型分子影像技术应用于生态/环境毒理学监测、评估研究的潜在价值.     

基于Fluent的搅拌流场模拟研究

使用Fluent对某钢厂KR脱硫搅拌工艺过程进行数值模拟,研究桨叶长度、搅拌头插入深度及转速对搅拌效果的影响。结果表明,尺寸为2B=1 300mm的长浆叶搅拌头搅拌效果较好,搅拌头插入深度为液面下800mm左右较为适宜,搅拌头转速以80～120r/min为宜。     

基于TFIDF算法的家庭关系识别模型构建及其应用

基于TFIDF(Term Frequency Inverse Document Frequency)算法,结合用户通话圈运用呼叫指纹方法分析用户的交往圈、呼叫特征、短信特征、位置特征、客服特征、终端特征等特征,构建家庭关系识别模型,进而挖掘家庭关联关系的手机与固话在呼叫圈相似度、平均每天通话次数、平均每次通话时长等变量上的相关性,为发现手机号码与家庭固定电话之间的关联关系提供了有效的技术手段,并有效地应用于固移捆绑套餐和可选套餐的目标客户的识别。从实际营销效果来看,该模型的使用有利于帮助市场营销人员快速、方便、有效地开展融合套餐的销售,在降低营销成本的同时提高了营销效果。