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371.
采用电生理学与行为学结合的方法,通过慢性微电极埋植技术及双脉冲检测技术,观察大鼠海马MF-CA3突触在明暗辨别学习过程中形成习得性长时程增强(Long-term potentiation, LTP)后双脉冲易化(Paired-pulse facilitation, PPF)效应的变化. 结果表明:Mossy fibers-CA3(MF-CA3)突触习得性LTP形成前的PPF易化率为138.36%9.25%,形成后则为114.75%8.42%,差异极显著(p 0.01),而基线对照组在长达7天的检测中,PPF易化率稳定在140%左右. 研究结果显示,MF-CA3突触的习得性LTP的表达可能与突触前递质释放的改变有关. 相似文献
372.
陈晓 《江西科技师范学院学报》2009,(2):87-90
多年的英汉对比研究表明,英语表现为静态性语言,汉语则是动态性语言。本文通过列举近几十年来奥斯卡获奖英语电影片名的翻译和个别电影名称的几个译本,表现了英汉翻译中的“动静相宜”。同时提出在影片的翻译策略上,归化和异化相比较而言,归化对于目的语观众似乎更加具有感召力。 相似文献
373.
Flavin-containing monooxygenase (FMO), like cytochrome P450 (CYP), is a monooxygenase that uses the reducing equivalents of NADPH to reduce one atom of molecular oxygen to water, while the other atom is used to oxidize the substrate. Recently, it was shown that some CYP isoforms have been subject to positive selection. However, it is unknown whether the highly conserved phase I detoxification enzyme, FMO, has undergone similar positive Darwinian selection. We used maximum-likelihood models of codon substitution, evolutionary fingerprinting, and cross species comparison to investigate the occurrence of adaptive evolution in FMO sequences. We used recent genomic data from a range of species, including vertebrates and invertebrates. We present the evidence for the occurrence of adaptive evolution in mammalian FMO 3, 4, 5, and fugu FMOs but not in mammalian FMO 1, FMO 2, frog FMOs, other fish FMOs and invertebrate FMOs. The sites under adaptive evolution were significantly associated with the insertion domain in mammalian FMO 5. We identified specific amino acid sites in FMOs 3–5 that are likely targets for selection based on the patterns of parallel amino acid change. The most likely role of adaptive evolution is the repair of mutations that permitted optimal NADP+ binding and improved catalytic efficiency. The occurrence of positive selection during the evolution of phase I detoxification enzymes such as FMOs 3–5 and fugu FMO suggests the occurrence of both high selection pressure acting on species within their unique habitats and significant changes in intensity and direction (forms of xenobiotics and drugs) resulting from changes in microhabitat and food. 相似文献
374.
腰鼓湾站自2009年投运以来,唐腰线(唐美站至腰鼓湾站)高频通道一直出现异常情况,之间经过多次的处理。文章通过处理该缺陷,既从局部来解决问题,又整体地对问题综合分析处理,研究了消除该通道的故障的措施。 相似文献
375.
面向新一代生物及化工产业的生物质原料炼制关键过程 总被引:2,自引:0,他引:2
木质纤维素等生物质本身是一个超分子功能体,是新一代生物及化工产业最具价值的工业通用原料。国家973计划项目“秸秆资源生态高值化关键过程的基础研究”研究团队经过为期5年的研究,建立了以秸秆为代表的生物质高效转化关键过程和技术平台。但是,要在生物质经济的全球竞争中形成优势,还需突破制约生物质成为通用原料的基础问题。本文分析了面向新一代生物及化工产业的生物质产业发展特点和亟需解决的主要问题,提出了符合生物质原料结构特点和产物功能要求的生物质原料炼制过程新思路,将生物质原料炼制思路从原料预处理.组分分离提升到选择性结构拆分,并阐明了生物质成为新一代生物及化工产业通用工业原料需要解决的关键科学问题。 相似文献
376.
Kiseon Kim 《系统工程与电子技术(英文版)》2011,22(5):840-847
The application of protograph low density parity check(LDPC) codes involves the encoding complexity problem.Since the generator matrices are dense,and if the positions of "1" s are irregularity,the encoder needs to store every "1" of the generator matrices by using huge chip area.In order to solve this problem,we need to design the protograph LDPC codes with circular generator matrices.A theorem concerning the circulating property of generator matrices of nonsingular protograph LDPC codes is proposed.The circulating property of generator matrix of nonsingular protograph LDPC codes can be obtained from the corresponding quasi-cyclic parity check matrix.This paper gives a scheme of constructing protograph LDPC codes with circulating generator matrices,and it reveals that the fast encoding algorithm of protograph LDPC codes has lower encoding complexity under the condition of the proposed theorem.Simulation results in additive white Gaussian noise(AWGN) channels show that the bit error rate(BER) performance of the designed codes based on the proposed theorem is much better than that of GB20600 LDPC codes and Tanner LDPC codes. 相似文献
377.
378.
郭效 《科技情报开发与经济》2009,19(28):47-49
针对目前高校多校区办学模式下图书馆文献资源配置所面临的问题,提出了多校区模式下馆藏资源重组优化配置应遵循的原则和应采取的方法。 相似文献
379.
活性炭负载纳米零价铁去除溴酸盐的研究 总被引:1,自引:0,他引:1
实验采用液相还原法制备活性炭负载纳米零价铁材料(nZVI/AC),并利用X射线衍射(XRD)、扫描电镜(SEM)和透射电镜(TEM)等对其结构进行表征.考察了不同反应条件下nZVI/AC对BrO3-的去除效率,并研究其去除机理.结果表明nZVI/AC具有很高的表面反应活性,且nZVI和活性炭(AC)之间存在协同作用. BrO3-的去除效率随 pH 值的减小而增大, 共存离子NO3-和SO42-对其去除率影响不大但降低了去除速率.机理分析表明BrO3-被nZVI/AC吸附而使局部BrO3-浓度升高,并被nZVI迅速还原为无毒的Br-. 相似文献
380.
LI Mi LIU LianQing XI Ning WANG YueChao DONG ZaiLi XIAO XiuBin ZHANG WeiJing 《科学通报(英文版)》2013,58(13):1516-1519
Atomic force microscopy (AFM) was used to locate CD20 molecules on the surface of lymphoma Raji cells. Rituximab (a monoclonal antibody against CD20) molecules were linked onto the AFM tip via a polyethylene glycol (PEG) linker. Raji cells were adsorbed onto glass slides coated with poly-L-lysine. First, the CD20 distribution in a local area of the cell surface was visualized using the AFM lift scan mode. Second, 16 × 16 force curves were obtained from the same cell area to construct the CD20-rituximab binding force map. Finally, free rituximab was added to block the CD20 molecules on the cell surface and the lift phase image and CD20-rituximab force map were obtained again. The experimental results indicated that when the lift height was greater than the length of the PEG linker, no recognition sites were observed in the lift phase image. However, as the lift height decreased to the length of the PEG linker, some recognition sites were observed in the lift phase image and these sites were generally consistent with the pixels in the force map. After blocking, both the recognition sites in the lift phase image and the gray pixels in the binding force map decreased markedly. These results can improve our understanding of the distribution of protein molecules on the cell surface and facilitate further investigations into cellular functions. 相似文献