Petrology, geochemistry and geodynamics of basic granulite from the Altay area, North Xinjiang, China

The basic granulite of the Altay orogenic belt occurs as tectonic lens in the Devonian medium- to lower-grade metamorphic beds through fault contact. The Altay granulite (AG) is an amphibole plagioclase two-pyroxene granulite and is mainly composed of two pyroxenes, plagioclase, amphibole and biotite. Its melano-minerals are rich in Mg/(Mg Fe^2 ),and its amphibole and biotite are rich in TiO2. The AG is rich in Mg/(Mg Fe^2 ), Al2O3 and depletion of U, Th and Rbcontents. The AG has moderate ∑REE and LREE-enriched with weak positive Eu anomaly. The AG shows island-arc pattern with negative Nb, P and Ti anomalies, reflecting that formation of the AG may be associated with subduction. Geochemical and mineral composition data reflect that the protolith of the AG is calc-alkaline basalt and formed by granulite facies metamorphism having peak P-T conditions of 750℃-780℃ and 0.6-0.7 Gpa. The AG formation underwent two stages was suggested. In the early stage of oceanic crustal subduction, calc-alkaline basalt with island-arc environment underwent granulite facies metamorphism to form the AG in deep crust, and in the late stage, the AG was thrust into the upper crust.     

Ant colony system algorithm for the optimization of beer fermentation control

Beer fermentation is a dynamic process that must be guided along a temperature profile to obtain the desired results. Ant colony system algorithm was applied to optimize the kinetic model of this process. During a fixed period of fermentation time, a series of different temperature profiles of the mixture were constructed. An optimal one was chosen at last. Optimal temperature profile maximized the final ethanol production and minimized the byproducts concentration and spoilage risk. The satisfactory results obtained did not require much computation effort.     

上海青少年女性消费者研究及服装品牌企划

通过AIOV分析法对上海青少年女性消费者的研究,得到了该市场消费群的总体特征。根据对此目标市场的分析,制定了服装品牌“Cacao”的企划案。这里明确提出了一种应对服饰消费感性化需求创设个性化品牌的预测提案型策略。     

VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

Vascular endothelial growth factor (VEGF) is a principal regulator of blood vessel formation and haematopoiesis, but the mechanisms by which VEGF differentially regulates these processes have been elusive. Here we describe a regulatory loop by which VEGF controls survival of haematopoietic stem cells (HSCs). We observed a reduction in survival, colony formation and in vivo repopulation rates of HSCs after ablation of the VEGF gene in mice. Intracellularly acting small-molecule inhibitors of VEGF receptor (VEGFR) tyrosine kinase dramatically reduced colony formation of HSCs, thus mimicking deletion of the VEGF gene. However, blocking VEGF by administering a soluble VEGFR-1, which acts extracellularly, induced only minor effects. These findings support the involvement in HSC survival of a VEGF-dependent internal autocrine loop mechanism (that is, the mechanism is resistant to inhibitors that fail to penetrate the intracellular compartment). Not only ligands selective for VEGF and VEGFR-2 but also VEGFR-1 agonists rescued survival and repopulation of VEGF-deficient HSCs, revealing a function for VEGFR-1 signalling during haematopoiesis.     

关于老子思想现代意义的哲学反思

老子的思想可,包含了四方面的精华,对现今人类仍具广泛的现实意义：一是“无为而无不为”的政治艺术;二是“绝学无忧”,对科技与文化异化状态的超越;三是自然而然的生态伦理;四是不为物役,重身轻名的人生哲思。     

供应链中供应商评价模型的构建及优化选择

供应链管理 ( SCM)是在 IT技术广泛应用的基础上产生的一种先进、新颖的管理哲理与方法 .SCM强调“双赢”竞合模式下的优化问题 .而对供应商的正确评价与选择则是实现其全局性优化的重要一环 .本文从制造商的角度构建了一个对供应商的评价模型 ,并采用 AHP方法进行了优化选择研究     

计算机教学机房的建设、管理与维护

针对计算机教学机房的建设、管理与维护,介绍了一些有效可行的保证机房正常、稳定运行的“软”保护方法,不需任何投资、不存在兼容性问题,且快速、方便。     

设计:沟通科学与人文的第三种文化

设计既与现实生产的制造和运行相联系 ,又与美学和社会伦理道德规范相联系 ,因而成为科学文化与人文文化统一的微观现实机制和中介环节。在信息时代 ,设计者为了控制硬件结构的非秩序幽灵 ,创造出了一种“非物质文化” ,即“软件形式”。设计的重心已经不再是一种有形的产品 ,而是一套抽象的“关系” ,即无形的、人与机器的语言对话。为此 ,应该更新工业社会关于技术、产品、市场的开发设计等传统观念 ,克服传统的工业设计在“满足人的无限丰富的需要”这一本质层面上的盲区 ,确立包括工业工程设计和社会工程设计相统一的广义设计观念。最后 ,文章分析了现代艺术与现代设计的关系 ,展示了两者日趋融合的发展趋势     

中日铁路项目国民经济评价方法比较与分析

以日本《铁路费用效益分析手册 (99版 )》和中国《铁路建设项目经济评价办法 (第 2版 )》为参照 ,通过对比分析中日铁路项目国民经济评价方法的差异 ,提出日本铁路费用效益分析方法中的可借鉴之处 :借鉴日本评价方法分 3类界定受益群体的思路 ,解决我国现行方法存在的效益重复计算问题 ;以福利经济学和“有无对比法”作为项目评价的基本指导原则 ,解决我国由于评价原则模糊导致的同一项目不同评价结论的问题等     

Induced recovery of defective membrane expression of a CC chemokine receptor 5 mutant by phytohemagglutinin

CC chemokine receptor 5 (CCR5) is a member of the G-protein-coupled receptor superfamily. It plays an important role in macrophage tropic human immunodeficiency virus-1 entry and in some inflammatory reactions. CCR5-893(–) is a single-nucleotide deletion that results in complete truncation of the C tail of the gene product. We detected CCR5-893(–) in a sample of patients infected with non-tuberculosis mycobacteria and found that it was maintained heterozygously with a frequency of 2%. There is no association between this mutation and any immunodeficiency. Membrane expression of CCR5-893(–) was substantially reduced compared to the wild type, but this defective surface presentation recovered greatly recovered in the presence of 2 mg l-1 phytohemagglutinin (PHA). However, PHA inducement did not affect the total intracellular expression of CCR5-893(–) or wild-type CCR5. Thus we suggest there exist some PHA-induced factor(s) that could mediate the presentation of truncated CCR5.Received 23 July 2003; accepted 18 August 2003