Experimental Study and Numerical Simulation of the Casting-Forging Complex Near Net Forming of Alternator Claw-pole

As a newly developed precision technology, casting-forging complex near net forming process is utilized to produce complex components with a short lead time, low cost and high precision, thus to accelerate the response speed of the market and enhance the competitive power of products. In this paper, the casting-forging complex near net forming process of alternator claw pole was developed and investigated with a combination of experimental and numerical simulation method. Qualified near net workpiece was manufactured, mechanical parameter and relative field information during the forming process was also obtained. While the alternator claw-pole is processed with this technology, the forming force is small, the process is short and the quality of forgings is perfect. Therefore, the complex casting-forging near net forming process of claw-pole is an energy and material saving technology, which will have a vast developing and application prospect in the future.     

A Theoretical Approach for Estimating Fracture Toughness of Ductile Metals

Fracture toughness is very important when applying Damage Tolerance Design and Assessment Techniques. The traditional testing approach for obtaining fracture toughness values is costly and time consuming. In order to estimate the fracture toughness of ductile metals, the fracture mechanics theory, materials plastic deformation theory and materials constructive relationships are employed here. A series of formulae and a theoretical approach are presented to calculate fracture toughness values of different materials in the plane stress and plane strain conditions. Compared with test results, evaluated values have a good agreement.     

神经激素对配子细胞发生的影响及其作用

神经激素对生殖细胞的发生起关键性的调控作用.就神经激素对脊椎动物,无脊椎动物的 配子发生的影响及其作用的研究现状作了简要的综述,在无脊椎动物中主要对昆虫配子发生的神 经激素调控做了介绍.     

利用URL-Key领域术语识别方法

首次提出利用URL-Key进行领域术语识别的方法。以URL作为媒介, 借助已知URL-Key的领域性来判断未知领域候选术语的领域性。首先, 借助互联网中已有的人工分类领域URL, 根据URL-Key在各领域汇总使用的频度, 采用基于方差的领域URL-Key识别方法, 构建领域URL-Key词表; 然后, 利用伪反馈技术, 收集候选领域词检索得到的URL结果集, 根据URL结果集构建候选领域术语的URL-Key特征向量; 最后, 利用SVM对候选领域术语进行提取。在4个领域进行实验, 都取得不错的效果。新提出的方法可以有效地解决低频术语识别问题, 为低频术语的识别提供新的思路。     

基于深度极限学习机的高光谱遥感影像分类研究

高光谱遥感数据越来越普及并为人们广泛使用,基于高光谱遥感数据的地面物体精确分类是高光谱遥感技术的核心应用之一.针对高光谱遥感影像的分类问题,提出一种基于深度极限学习机(D-ELM)的分类方法.该方法利用一种新的深度学习模型——深度极限学习机对高光谱遥感影像进行分类,并与基于极限学习机(ELM)、支持向量机(SVM)、核极限学习机(ELMK)分类方法进行了比较分析.研究结果表明:相对于ELM、SVM、ELMK分类方法,D-ELM分类方法能够更加准确地挖掘高光谱遥感影像的空间分布规律,提高分类的准确度.     

尾矿库溃坝灾害防控现状及发展

尾矿库溃坝灾害应急响应时间短、潜在威胁巨大,往往造成惨重人员伤亡与巨额财产损失.近些年尾矿库安全事故发生数量的总体下降趋势充分体现出现代化技术及安全管理方面的进步,然而重大事故发生频次却不减反增,2015年巴西Samarco铁矿与2014年加拿大Mount Polley重大溃坝事故及其惨重后果,再次为尾矿库安全敲响警钟.我国现存尾矿库8869座,含"头顶库"1425座,安全形势复杂.本文在收集大量相关领域文献的基础上,聚焦尾矿库溃坝灾害防控体系中的安全监测、灾害预警与应急准备、安全管理与标准规范这三大方面核心内容,分别综述对比国内外现状及前沿进展,探讨分析我国当前所面临的问题并尝试提出改进建议,为尾矿库防灾减灾理论研究与技术革新提供参考.结果表明:(1)我国尾矿库安全监测标准更高,但仪器耐久性、可靠度与实用性不足,专用监测器件与新技术的研发应用势在必行;(2)灾害预警方法单一且可信度不高,而信息技术融合应用成为发展趋势;(3)应急管理与预警决策需以充分的科学论证为基础,当前研究在试验手段与计算方法上存在局限;(4)我国拥有完善的安全管理标准规范体系,但在安全等别划分、全生命周期管理、主体变更、事故总结等方面相对欠缺.     

转炉炼钢的物料结构优化

利用60 t转炉研究了采用不同含铁物料及不同比例石灰石炼钢时的钢铁料消耗、氧气消耗量和煤气产生量的变化规律.研究发现：当采用铁水作为原料，渣钢和块矿作为冷却剂时，钢铁料消耗最低，仅为1072.07 kg·t-1；当采用铁水和废钢作为原料，配有磁选渣铁时，钢铁料消耗最高，达到1092.91 kg·t-1；随着石灰石加入量的增加，钢铁料消耗增加，氧耗略有降低，吨钢煤气产生量增加.研究结果为炼钢过程优化物料结构、降低生产成本提供了新的方法.     

Disruption of calcitonin gene-related peptide signaling accelerates muscle denervation and dampens cytotoxic neuroinflammation in SOD1 mutant mice

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease. Neuronal vacuolization and glial activation are pathologic hallmarks in the superoxide dismutase 1 (SOD1) mouse model of ALS. Previously, we found the neuropeptide calcitonin gene-related peptide (CGRP) associated with vacuolization and astrogliosis in the spinal cord of these mice. We now show that CGRP abundance positively correlated with the severity of astrogliosis, but not vacuolization, in several motor and non-motor areas throughout the brain. SOD1 mice harboring a genetic depletion of the βCGRP isoform showed reduced CGRP immunoreactivity associated with vacuolization, while motor functions, body weight, survival, and astrogliosis were not altered. When CGRP signaling was completely disrupted through genetic depletion of the CGRP receptor component, receptor activity-modifying protein 1 (RAMP1), hind limb muscle denervation, and loss of muscle performance were accelerated, while body weight and survival were not affected. Dampened neuroinflammation, i.e., reduced levels of astrogliosis in the brain stem already in the pre-symptomatic disease stage, and reduced microgliosis and lymphocyte infiltrations during the late disease phase were additional neuropathology features in these mice. On the molecular level, mRNA expression levels of brain-derived neurotrophic factor (BDNF) and those of the anti-inflammatory cytokine interleukin 6 (IL-6) were elevated, while those of several pro-inflammatory cytokines found reduced in the brain stem of RAMP1-deficient SOD1 mice at disease end stage. Our results thus identify an important, possibly dual role of CGRP in ALS pathogenesis.