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991.
HeChun-yan ZhouXin LiXiao-ming YuHong HongJia-ling 《武汉大学学报:自然科学英文版》2004,9(1):120-124
The present study was undertaken to investigate the effect of oxidized low density lipoprotein (oxLDL) on the expression of maerophage matrix metalloproteinase-12 (MMP-12), and the possible mechanisms. Activation of extracellular signal-regulated kinase 1/2 (ERK1/2) was detected by Western blot analysis.Enzymatic activity of MMP-12 was determined by β-casein zymography. RT-PCR analysis was used to measure the mRNA expression level of MMP-12. OxLDL-stimulated macrophages produced increased casein-degrading activities and oxLDL also significantly increased the mRNA level of MMP-12 in a dose-dependent manner.OxLDL stimulated the phosphorylation of ERK1/2 in macrophages. The use of the specific inhibitor indicated that the ERK1/2 signaling pathway was required for the induction of MMP-12.These data demonstrated that oxLDL induced MMP-12 expression in macrophages through an ERK1/2-dependent pathway. 相似文献
992.
Han Xiao-fang Zheng Lian-shuang Xie Yi-min . Department of Chemical Engineering Wuhan University of Technology Wuhan Hubei China . College of Chemical Environmental Engineering Jianghan University Wuhan Hubei China . The State Key Laboratory of Pulp Paper Engineering South China University of Technology Guangzhou Guangdong China 《武汉大学学报:自然科学英文版》2004,9(1):125-128
Xylanisthemajorcomponentofplantcellwallsandthemostabundantpentosaninnature.Xylancontainsβ 1,4 linkedd xylosebackboneswitharabinose,4 O methyl d glucuronicacid,andaceticacidsubstituents[1 ] .Thexylan degradingen zymesincludeendoxylanase(1,4 β d xylanxylanohydrolase;EC3.2 .1.8)and β xylosidase (1,4 β d xylanxylanohydrolase;EC 3.2 .1.37) .xylanasedegradesthexylanbackboneintoxylo bioseandxylooligosaccharides,whileβ xylosidasereleasesxylosylresiduesfromthenonreducingendsofxylooligosaccha… 相似文献
993.
Che Ka-jia Li Zhi-chen College of Management Huazhong University of Science Technology Wuhan Hubei China 《武汉大学学报:自然科学英文版》2004,9(2):149-152
0 IntroductionIntheprocessofR&Ditem ,thereisusuallycompetition .ManyfirmswanttoinvestR&Dtoobtainapatent.Lury[1 ] gaveanequilibriuminvestmentundertheconditionofone timeinvestmentandcontinuousinvestmentwhenthepayoffwasafixedprize.Ref.[2 ]analyzedtheeffectofinformationsharinginR&D .TherearemanyliteraturesaboutanalysisofR&DlevelswhenfirmscompeteinoutputmarketafterR&Dsucceeds[3 ,4] .Additionally ,todecideinvestmentlevel,therearemanyliteraturesaboutR&Ditem’spricing .MondherBellalah[5] ,K .… 相似文献
994.
WANGLong-hui HUMin ZHOUHuai-bei LIUJuan 《武汉大学学报:自然科学英文版》2004,9(6):962-966
A new method was presented to discuss the respective roles of short- and long-range interactions in protein folding. It‘s based on an off-lattice model, which is also being called as toy model. Simulated annealing algorithm was used to search its native conformation. When it is applied to analysis proteins lagt and laho, we find that helical segment catmot fold into native conformation without the influence of long-range interactions. That‘s to say that long-range interactions are the main determinants in protein folding. 相似文献
995.
A tetranuclear zinc benzoate Zr4O(C6H5CO2)6 was synthesized and characterized by X-ray single crystal determination. It crystallizes in cubic, space group Ia-3d. Its crystal cell is very large, α=4.10063(18)nm, V=68.953(5)nm^3 and Z=48. The structure is composed of discrete Zr4O(C6H5CO2)6 molecules. In each molecule, four zinc atoms are held together by a central oxygen atom, which results in the formation of a regular tetrahedron. All benzoate ligands coordinate to zinc atoms in a bidentate bridging mode. Each zinc atom is in a slightly distorted tetrahedral geometry, coordinated by three benzoate oxygen atoms and the central oxygen atom. The intermolecular interactions result in the formation of a three-dimensional supramolecular framework, with non-intersecting parallel channels. 相似文献
996.
HANLu ZHOUMan-li TIANJing KURTRothermel 《武汉大学学报:自然科学英文版》2004,9(6):931-934
A new algorithm called spatially aware routing algorithm with enhanced learning (SAREL) is proposed to guarantee the rationality of route selecting in inter-vehicle communication scenario. Firstly, the traffic model is discussed and set up by using Poisson distribution. Then we analyze the process of traffic evaluation with enhanced learning, and exploit movement estimation to assist state memorization. The improvement of algorithm is provided at last compared with our previous work. Simulation results show that SAREL algorithm could achieve better performance in packet delivery ratio, especially when network connection ratio is average. 相似文献
997.
YANGJian-wu 《武汉大学学报:自然科学英文版》2004,9(5):817-822
In this paper, an improved algorithm, named STC-I. is proposed for Chinese Web page clustering based on Chinese language characteristics, which adopts a new unit choice principle and a novel suffix tree construction policy. The experimental results show that the new algorithm keeps advantages of STC, and is better than STC in precision and speed when they are used to cluster Chinese Web page. 相似文献
998.
Twenty Yongzheng copper coins were fast dat-ing by X-ray energy dispersive spectrometer with scanning electron microscope (SEM-EDS) according to official ingredient. The 20 coins were classified in two groups according to the results. Group 1 represents the coins minted before AD 1 728 and group 2 represents the coins minted after AD 1 728. At concentration range (0.00%-5.13%), the distribution of lead is not homogeneous in the coins, and the largest diameter of lead inclusion is less than 15 μm. The official fineness degrade is supported. 相似文献
999.
XuGuo-xiong GanLiang-cai HuangTian-xi 《武汉大学学报:自然科学英文版》2004,9(1):73-77
This paper proposes a new multi-stage parallel interference cancellation scheme by modifying the conventional multi-stage parallel interference canceller (PIC). At each stage, it first converts the interference-cancelled outputs from previous stage into the a prior information, in terms of which the bit mean values are computed and the multi-access interferenee (MAI) for each user is evaluated, and then an interferenee cancellation is performed to obtain further interference suppression. To reduce the implementation complexity, wegive an approximation expression for bit mean value. The performance over AWGN channel is analyzed and compared to the conventional PIC. The user number K= 7 and spreading factor N= 13 are chosen as simulation parameters. The computer simulation results show that the proposed PIC has better performance than the conventional PIC both with 2 interference cancellation (IC) stages, at bit error rate of 10^-3 , for example, about 3 dB performance gain is obtained by using the proposed PIC. It is also shown that our proposed PIC with 1-stage is superior to the conventional PIC with 2-stage in performance, which is of practical value because PIC with fewer stages can bring about shorter processing delay. 相似文献
1000.
LITai-quan TIANMao XUJi-sheng 《武汉大学学报:自然科学英文版》2004,9(6):909-912
By analyzing the current distribution of Bow-Tie amerma used in short-pulse ground penetrating radar, the methods of antenna load and driving are presented in this paper to reduce strength of reflective wave both at antenna end and excitation point. The numerical simulation results show the strength oi reflective wave is smaller than -55dB comparing with the driving wave when the methods are adopted. 相似文献