An effective amperometric biosensor based on graphene modified gold nanowire arrays for glucose detection

A novel glucose biosensor based on graphene nanosheets （GNs） modified gold nanowire arrays （AuN- WAs） electrode was constructed. Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates. GNs were synthe- sized through a public route involving graphite oxidation, exfoliation, and chemical reduction. Field emission scan- ning electron microscope and high-resolution transmission electron microscope were employed to characterize the as- prepared AuNWAs and GNs. Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method. The cyclic voltam- metry results showed that the GNs-AuNWAs-based glu- cose biosensors have high catalysis activity to hydrogen peroxide （H2O2） than those modified with GNs or AuN- WAs only. Furthermore, amperometric response was employed to detect glucose concentration owing to its simplicity, high selectivity, and relative low cost. Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sen- sitivity of 40.25 μA cm^-2 （mmol/L）^-1, low detection limit of 0.02 mmol/L, and a linear range from 0.02 to 3 mmol/L.     

随机巨灾索赔相依风险模型的动态最优再保险

在索赔风险时变、相依条件下,建立随机巨灾的可调态再保险模型.在指明超额赔款再保险为最优分保形式的基础上,讨论并发现目标函数随自留巨灾风险水平的增大,在任意相依结构下均先减后增的变化定理,从而获得了自留向量的一般性显式表达式.根据巨灾风险的特征,还在一类特定的相依结构下,以自留风险的期望效用和方差为优化目标,对自留向量进行了更为明确的表示并给出具体示例.结果表明,随着巨灾风险相依强度的上升,分保的满意度降低,经营稳定性减弱,对保险公司的负面影响很大.此时,为实现客观风险下的分保目标最优,常规风险的自留水平应随之增大,体现了动态再保险的优越性.     

基于知识转移的组织学习机制研究

如何将组织学习从意识形态转换为组织中的学习的现实方法和工具,是学习型组织成功的关键环节。通过对组织知识转移过程中的学习方式和相应的组织学习机制的分析,探讨了组织如何根据不同的知识转移方式设计相应的组织学习机制的方法。     

高校图书馆员的心理健康刍议

随着社会的发展,高校图书馆员的心理健康受到威胁。分析了高校图书馆员常见的心理问题,提出了维护馆员心理健康的有效措施。     

车用材料有害物质管控策略研究

在源头加强车用材料有害物质管控,是促进汽车行业健康持续发展的重要途径。介绍了车用材料有害物质的主要危害、来源及替代趋势,分析了欧盟和中国有关车用材料有害物质标准法规的状况,给出了我国汽车企业管控策略,旨在提升法规应对能力和促进汽车工业优化升级。     

槐花米提取物对尿素酶的抑制活性

采用靛酚法研究了槐花米的乙醇、乙酸乙酯、二氯甲烷提取物对尿素酶的抑制作用，证实3种提取物均对尿素酶有明显抑制作用，IC₅₀分别是2.63，1.90，0.53 g/L.通过动力学研究阐明了提取物对尿素酶的抑制行为是可逆的混合型抑制，动力学常数K_i分别为0.32，0.22，0.084 g/L.首次阐明了槐花米中含有尿素酶抑制成分，为槐花米具有健胃、养胃的功效提供了一种理论解释.     

Glutenin macropolymer particles size distribution of six wheat varieties in eastern China

Size distribution of glutenin macropolymer(GMP) particles significantly affects the quality of final products in wheat. Six wheat varieties in eastern China were used for investigating the GMP content, particle size distribution and their relation. The results showed that the particle diameter of GMP changed from 0.38 μm to 269 μm. A typical bimodal curve of volume distribution of particles with peak values ranged from 4.44 μm to 5.36 μm and from 45.76 μm to 116.30 μm, respectively. Number distribution of particles showed the typical population with peak values in the range of 0.57-1.00 μm. Proportions of granules 12 μm, 12-80 μm and 80 μm were in the range of 17.1%-47.8%, 32.1%-50.3% and 10.2%-38.1% of total volume, respectively. The content of GMP was negatively correlated with the volume of GMP particles 12 μm, but positively correlated with the volume of particles 80 μm. The results suggested that the greater percentage of larger GMP particles is, the more GMP content there is in wheat grain.     

Acylation of nitriles to β-ketonitriles catalyzed by a heterometallic alkoxide cluster of neodymium and sodium： NdNa8（O^tBu）10（OH）

Catalytic acylation of nitriles with esters in the presence of 10 mol% NdNa8(OtBu)10(OH) is developed.The procedure is suitable for both enolizable and nonenolizable esters and affords β-ketonitriles in moderate to high yields.The heterometallic alkoxide cluster NdNa8(OtBu)10(OH) is structurally characterized by X-ray diffraction,and a mechanism for the production of β-ketonitriles using the cluster is proposed and verified.     

基于结构化模型驱动的稳控装置动作模拟仿真方法

提出了一种基于结构化模型驱动的稳控装置动作模拟仿真方法.通过对稳控装置模型的结构化,将其稳控策略组织为四元表形式(即故障、运行方式、潮流水平和控制策略),并将其控制策略分解为控制方式、控制量、控制量实施原则、控制对象队列和约束5个基本元素,在此基础上归纳出直接型、顺序型、循环型和最优型四种基本的控制策略结构化模型.进一...     

An important functional group,benzo[1,3]dioxole,of alkaloids induces the formation of the human telomeric DNA G-quadruplex

Over the past few decades, numerous molecules have been discovered or designed to interact efficiently and selectively with a peculiar DNA structure named G-quadruplex. Some of these molecules have been developed as anticancer agents. To aid the design of anticancer agents, the ability of alkaloids possessing Protoberberine and Benzophenanthridine groups to induce the formation of G-quadruplexes were studied using CD spectroscopy. By careful examination of their structures, we found that a benzo[1,3]dioxole group plays an important role in influencing their inductive properties. The more functional groups the alkaloids have, the stronger their G-quadruplex inductive ability.