EMRC和EMRL治疗上消化道早期癌及癌前病变

目的:探讨EMRC和EMRL两种EMR技术在上消化道早期癌及癌前病变中的临床应用价值。方法:18例病人(其中食管病变5例、胃内病变13例。超声内镜及病理检查早期胃癌1例、食管平滑肌瘤1例、增生性息肉7例、扁平腺瘤6例、不典型增生3例)。7例用EMRC、11例用EMRL技术进行了内镜下粘膜切除术。结果EMRC技术对食管平滑肌瘤、增生性息肉、扁平腺瘤、不典型增生的完全切除率分别为100%、100%、85.71%、85.71%,平均92.86%。而EMRL对胃早期胃癌,增生性息肉,扁平腺瘤,不典型增生的完全切除率分别为100%、100%、90.91%、90.91%,平均95.46%。结论EMRC和EMRL对上消化道早期癌、癌前期病变、黏膜下肿瘤及宽基息肉等均有较高的完全切除率。作为一项微创内镜技术,可替代部分胃肠道早期癌肿的外科手术治疗,降低治疗费用,且创伤性小,并发症少,疗效可靠,具有广阔的临床应用前景。     

集群污染源颗粒物允许排放量调控

 以包钢工业园区采暖期颗粒物排放清单为基础,利用CALPUFF大气扩散模型进行集群污染源允许排放量动态调控,其模拟调控结果可为污染物排放控制对策、措施的制定提供一定的理论指导,有助于实现包钢工业园区大气环境稳定达标.模拟结果表明,集群污染源单位排污量对控制点浓度贡献随着污染源高度的增加而降低,低矮点源和面源应作为控制重点.在采暖期气象条件不利于污染物扩散的条件下,集群污染源最大允许排放量减少到现有排放量的8.82%,而在气象条件有利于污染物扩散的条件下,其最大允许排放量减少到现有排放量的12.03%,可以实现控制区大气环境质量达标.     

On <Emphasis Type="Italic">k</Emphasis>-error linear complexity of some explicit nonlinear pseudorandom sequences

Combining with the research on the linear complexity of explicit nonlinear generators of pseudorandom sequences, we study the stability on linear complexity of two classes of explicit inversive generators and two classes of explicit nonlinear generators. We present some lower bounds in theory on the k-error linear complexity of these explicit generatol＇s, which further improve the cryptographic properties of the corresponding number generators and provide very useful information when they are applied to cryptography.     

细胞周期检测作为生物相容性评价指标的研究

应用体外细胞培养法,观察不同质量分数羟基磷灰石浸提液对L-929细胞的细胞学形态的影响,同时采用MTT比色法评价羟基磷灰石对L-929生长和增殖的影响,流式细胞仪检测羟基磷灰石浸提液对L-929 细胞生长周期及凋亡的影响.结果表明,羟基磷灰石浸提液对体外培养的细胞形态无明显影响,对细胞生长和增殖无明显抑制作用;不同质量分数材料浸提液的细胞毒性为0～1级;随羟基磷灰石浸提液质量分数的升高,细胞凋亡率逐渐上升;50%、75%、100%羟基磷灰石浸提液组能明显降低G0/G1期细胞比例,增加S,G2/M期细胞比例,能增加L-929细胞DNA的合成,促进细胞生长和组织修复.细胞周期检测是生物材料生物相容性评价的一种可靠方法和指标.     

“数据科学与大数据的科学原理及发展前景”——香山科学会议第462次学术讨论会专题论坛香山科学会议第次学术讨论会专题论坛：大数据环境下管理科学领域相关问题探讨

近年来,“大数据”作为热门话题,在学术研究领域及日常媒体环境中均受到广泛关注。本文简述了大数据环境下的管理模式在公共管理、工商管理和管理工程这三个方面的体现,并列举了目前我国在电子商务、智慧农业、金融业、环境治理、文化产业、传统医学领域已经有较好发展的大数据应用案例。最后针对大数据环境下的管理创新所面临的问题,提出了一些发展的思路和思考,分析了基于大数据的管理模式创新发展趋势。     

Effects of Si on the stability of retained austenite and temper embrittlement of ultrahigh strength steels

Effects of silicon (Si) content on the stability of retained austenite and temper embrittlement of ultrahigh strength steels were investigated using X-ray diffraction (XRD), transmission electron microscopy (TEM), and other experimental methods. The results show that Si can suppress temper embrittlement, improve temper resistance, and hinder the decomposition of retained austenite. Reversed austenite appears gradually with the increase of Si content during tempering. Si has a significant effect on enhancing carbon (C) partitioning and improving the stability of retained austenite. Si and C atoms are mutually exclusive in lath bainite, while they attract each other in austenite. ?-carbides are found in 1.8wt% Si steel tempered at 250℃, and they get coarsened obviously when tempered at 400℃, leading to temper embrittlement. Not ?-carbides but acicular or lath carbides lead to temper embrittlement in 0.4wt% Si steel, which can be inferred as cementites and composite compounds. Temper embrittlement is closely related to the decomposition of retained austenite and the formation of reversed austenite.     

HPSEPS软件包及其千核应用

基于自主开发的并行软件包HPSEPS所提供的大规模对称特征问题并行求解器,讨论了对称特征问题的并行计算方法,给出了HPSEPS的架构.HPSEPS软件包开发基于多级并行实现技术,并提供包括求解稠密和稀疏特征问题在内的多个并行求解器.在深腾7000平台上对不同大规模特征问题的并行求解进行了性能测试,实验结果表明HPSEPS在上千处理器核上具有很好地可扩展性.通过第一性原理,在上千处理器核上将Si金刚石结构计算由400个原子提升到2 000个原子,并给出了1 200个原子碳纳米管和纳米量子点计算.     

Cloning and expression pro?les of 15 genes encoding WRKY transcription factor in wheat (Triticum aestivem L.)

WRKY proteins are involved in various physiological processes, including biotic and abiotic stress responses, hormone responses and development. However, no systematic identi?cation, expression and function analysis of WRKY genes in wheat were reported. In this study, we isolated 15 wheat cDNAs with complete open reading frame (ORF) encoding putative WRKY proteins using in silico cloning. Phylogenetic analysis indicated that the 15 wheat WRKY genes belonged to three major WRKY groups. Expression analysis revealed that most genes expressed drastically in leaf, except TaWRKY10 which expressed in crown intensively. Four genes were strongly up-regulated with the senescence of leaves. Eight genes were responsive to low temperature, high temperature, NaCl or PEG treatment. Moreover, differential expression patterns were also observed between wheat hybrid and its parents, and some genes were more responsive to PEG treatment in the hybrid. These results demonstrated that wheat WRKY genes are involved in leaf senescing and abiotic stresses. And the changed expression of these WRKY genes in hybrid might contribute to the heterosis by improving the stress tolerance in hybrids. 2007 National Natural Science Foundation of China and Chinese Academy of Sciences. Published by Elsevier Limited and Science in China Press. All rights reserved.     

龙浦高速公路高液限土路基改良研究

论述了高液限土的物理特性和工程特性,介绍了目前常用的高液限土处理方法,对浙江省龙浦高速公路的高液限土进行了室内改良试验,得出了不同处理方法的改良效果.铺筑了采用掺灰、掺碎石和掺砂改良的高液限土试验路,对掺灰路段采用路拌法和包芯法的施工工艺,并进行了相应的观测,初步明确了掺灰、掺碎石和掺砂改良高液限土路基的稳定效果.     

振动激励下地铁沿线建筑物振动测试与数值分析

对广州地铁三号线沿线临近建筑物的振动响应进行了实测,并结合数值计算研究了地铁振动在建筑结构内的传播规律.研究结果表明:在框架结构中,随着建筑物高度的增加,振动峰值逐渐减小;地铁振动在建筑物内引起的振动时程的频率集中在30~80 Hz频段内,以30~50Hz频段为主;结构内部构件柱的振动衰减要比周边构件更加显著,柱上的梁越多,能量的损耗就越大;地铁振动引起的加速度值有可能对建筑物中使用人群的舒适度造成影响.