双网卡服务器流量分担策略

提出了双网卡服务器的流量分担策略，利用DNS的负载均衡，在每个网卡上都分担相应的流量，提高了网络性能，而且不需对访问其服务的客户机进行另行配置，使双网卡服务器在网络服务中能充分利用自身的资源。     

全球经济萧条与生产据点向中国的转移--21世纪亚洲工业化的新阶段

20世纪后期是亚洲工业化第一阶段,中国经济迅速发展,成为世界经济增长中心.外国资本纷纷投入中国市场,中国国内改革进入新的阶段.这对形成中国在内的亚洲经济圈,进入亚洲工业化第二阶段是至关重要的.     

RNAi-mediated gene silencing in non-human primates

The opportunity to harness the RNA interference (RNAi) pathway to silence disease-causing genes holds great promise for the development of therapeutics directed against targets that are otherwise not addressable with current medicines. Although there are numerous examples of in vivo silencing of target genes after local delivery of small interfering RNAs (siRNAs), there remain only a few reports of RNAi-mediated silencing in response to systemic delivery of siRNA, and there are no reports of systemic efficacy in non-rodent species. Here we show that siRNAs, when delivered systemically in a liposomal formulation, can silence the disease target apolipoprotein B (ApoB) in non-human primates. APOB-specific siRNAs were encapsulated in stable nucleic acid lipid particles (SNALP) and administered by intravenous injection to cynomolgus monkeys at doses of 1 or 2.5 mg kg(-1). A single siRNA injection resulted in dose-dependent silencing of APOB messenger RNA expression in the liver 48 h after administration, with maximal silencing of >90%. This silencing effect occurred as a result of APOB mRNA cleavage at precisely the site predicted for the RNAi mechanism. Significant reductions in ApoB protein, serum cholesterol and low-density lipoprotein levels were observed as early as 24 h after treatment and lasted for 11 days at the highest siRNA dose, thus demonstrating an immediate, potent and lasting biological effect of siRNA treatment. Our findings show clinically relevant RNAi-mediated gene silencing in non-human primates, supporting RNAi therapeutics as a potential new class of drugs.     

氯化镁用于染料废水的脱色研究

研究了MgCl_2处理若干种类的活性染料及分散染料的脱色效果,比较了MgCl_2/Ca(OH)_2、Al_2(SO_4)_3.PAC、FeSO_4/Ca(OH)_2的脱色效果。探讨了MgCl_2的脱色机理。实验结果表明,MgCl_2的脱色效果与染料种类、脱色的pH条件,脱色剂的用量有关;MgCl_2的脱色率随pH值升高而增加,对于活性染料废水,当pH=12.5左右时脱色率达最佳;对于分散染料废水,pH=12.0左右时脱色率达最佳;MgCl_2/Ca(OH)_2的脱色效果优于 PAC、Al_2(SO_4)_3、FeSO_4/Ca(OH)_2的脱色效果;MgCl_2的脱色机理为:(1)Mg~(2+)能与含有—OH,—SO_3H、—COOH基因的染料化合物起反应,生成稳定的螯合物,该螯合物在碱性条件下通过混凝作用从水中分离出来;(2)MgCl_2在高pH值下依靠水解生成的Mg(OH)_2胶体沉淀物对染料分子的吸附和卷扫沉降作用达到脱色目的。     

探空火箭图像系统设计方案

作为一种理想的实验平台,探空火箭在微重力科学领域得到了广泛应用.利用探空火箭进行微重力实验,首要问题是如何将实验过程以图像形式记录下来,并实时传回地面台站.因此,箭上图像的实时采集、编码与传输对实验具有重要作用.根据探空火箭微重力实验图像的特点,提出了一种适合于探空火箭图像系统的设计方案.按照该方案,图像系统可根据微重力实验的科学需求.实时调节实验图像的分辨率、帧速率和压缩比.该系统中,箭上的小波压缩单是核心模块,它通过基于硬件级的小波自适应压缩算法实现图像的箭上实时压缩,解码和实时显示则由与之对应的地面小波解码单元完成.     

计算机景观仿真技术在城市规划设计中的应用

计算机图形、图像处理技术在城市规划建筑设计中得到了广泛应用。以当前各种计算机景观仿真技术的基本原理为基础，从工作成本、设备要求、仿真效果、使用条件等方面进行了讨论、比较，为城市规划、建筑设计工作者的合理选择提供参考。     

304L不锈钢在核电一回路水中应力腐蚀行为的研究

 在模拟核电一回路高温高压水环境中,采用慢应变速率拉伸试验方法,研究温度对304L不锈钢应力腐蚀开裂的影响规律。通过扫描电镜观察,对试样断口形貌进行分析。结果表明,在高压水环境中,随着温度的升高,材料有向脆性断裂转变的倾向,抗拉强度等参数变化不大,延伸率和断面收缩率略有降低;在研究温度范围内,304L不锈钢试样断口未发现明显脆性解理特征;温度处于200-345℃区间时,没有发现存在304L不锈钢敏感温度,材料应力腐蚀敏感性较低。     

某类重特大火灾数值模拟研究

某酒吧火灾、深圳舞王俱乐部火灾和福建长乐拉丁酒吧火灾的发生场所和火灾原因类似,且短时间就造成大量人员伤亡,研究这类火灾防控措施有较好的意义。本文利用FDS软件构造某酒吧的火灾模型,合理分析场所的人员情况设定疏散模拟参数,根据火场情况设定合适的火灾场景,分析热辐射、烟气温度、烟气毒性、烟气能见度等参数的变化过程,并得到可用疏散时间。结合CFE软件进行人员疏散过程模拟,模拟的预期火灾人员伤亡与实际情况较好相符;并对不同的可燃物类型、消防设施状况和待疏散人数进行火灾后果分析,可燃物分析结果说明装修用聚氨酯泡沫吸音棉是造成火灾极速蔓延的直接原因,这类材料产生大量的有毒浓烟,很快就造成人员伤亡;不同消防设施模拟分析的结果体现了自动消防设施的重要作用,公共娱乐场所的自动喷水灭火系统应推广快速响应喷头,未按国家标准安装自动消防设施是造成重大火灾人员伤亡的成灾原因;对酒吧不同待疏散人数的火灾预期伤亡数定量分析证明了公共娱乐场所定员管理的重要意义;模拟分析的结果可用于此类火灾成因分析和火灾防控措施研究。     

Serum levels of perfluorinated compounds in the general population in Shenzhen, China

Perfluorinated compounds (PFCs) have been detected in many environmental matrices, biota, and nonoccupationally exposed populations in China recently. However, little is known about the distribution and levels of various PFCs in the general population living in areas where there is PFC exposure. In the present study, the levels and prevalence of ten target PFCs were determined in 227 serum samples from a population of nonoccupationally exposed individuals in Shenzhen, China. Results indicated that human exposure to PFCs was prevalent in Shenzhen. Perfluorooctanoate (PFOA) was the dominant PFC contaminant in the serum samples, with a median concentration of 6.72 ng/mL, followed by perfluorooctane sulfonate (PFOS) with a median concentration of 2.07 ng/mL. Other PFCs were detected at much lower concentrations, with median concentrations ranging from 0.02 to 0.87 ng/mL. Statistically, no significant (P>0.05) gender differences were observed for any of the PFCs. Significant (P<0.01) positive correlations were found between age and serum concentrations of the target PFCs, except for perfluorobutane sulfonate (R = 0.16, P = 0.01), perfluorohexanoic acid (R = 0.08, P = 0.22), and perfluoroheptanoic acid (R = 0.11, P = 0.10). Based on the one-compartment pharmacokinetic model, the total daily intakes of PFOA and PFOS for the general population in Shenzhen were calculated as 0.63 and 0.20 ng/kg body weight/day, respectively.     

聚苯胺修饰石墨烯纳米片的分散行为

针对氧化石墨(GO)用化学方法还原为石墨烯纳米片(GN)后极易再配列为类似石墨结构层状物的问题,本工作在GO还原过程中用聚苯胺(PANI)修饰石墨烯纳米片(P-GN),发现即使干燥后,P-GN仍可在N,N-二甲基甲酰胺(DMF)中呈分散状态稳定存在.