中国公共安全科技问题分析与发展战略规划研究

在给出公共安全系统性定义的基础上提出了公共安全综合指数的概念,讨论了不确定性的特点和系 统非优分析的方法,同时建立了公共安全运行体系。基于安全指数给出了公共安全控制能力指数,并且讨论了 不确定因素的分析方法。研究表明,公共安全科技贡献率是科技发展战略研究的关键,建立了科技投入与公共 安全目标函数,并且讨论了科技贡献增长率的投入产出关系。     

小波变换及其在语音信号处理中的应用

人们为了了解自然界的规律,或是为了解决工程中的一些问题,需要对各种各样的信号进行分析,在小波变换出现以前,应用最广泛的是傅立叶变换.但是在利用傅立叶变换分析信号时,存在着某些缺陷.小波变换基于海森堡测不准原理解决了局部时间信号分析的难题,发展了信号分析的方法,成为了当代信号分析的主要工具之一.由于语音信号的复杂性,以及在某些方面与小波变换的相似性,使小波变换在语音信号处理有着很广泛的应用.本文对小波变换及其在语音信号处理中的应用进行了简要的综述.     

跳跃扩散型离散几何平均亚式期权的定价

在股票市场有重大信息公布时,股票价格会发生跳跃.在股票价格服从Ito-Skorohod跳跃扩散过程的条件下,运用概率论的方法研究离散几何平均亚式期权的定价,并得出其定价公式.     

城市疫情传播和复工强度建模及相关性分析

以多源大数据为基础构建模型,分析全国34个典型城市因疫情导致的人口迁徙变化和人力缺口,并通过迁徙基数推算其他各城市的复工强度。仿真结果证明SEIR仓室模型能够较好地模拟此次疫情发展趋势,利用其估计各城市内部新型冠状病毒感染肺炎的基本再生数,结合人力缺口对复工强度进行回顾性的矩阵分析,以总结我国此次抗疫经验。相关性分析阶段对K-means无监督聚类后的城市集群进行回归分析,结果表明对于大部分城市而言,复工强度的大小与其人力缺口、基本再生数以及人均GDP水平有明显的相关关系。     

固体渗硼及其在模具冷冲头上的应用

在总结前人经验的基础上,以解决生产中出现的实际问题为宗旨,探讨以硼铁(Fe-B,20%B)为基的固体渗硼及其在模具冷冲头上的应用。     

Interleukin-33 stimulates formation of functional osteoclasts from human CD14+ monocytes

Interleukin (IL)-33 is a recently described pro-inflammatory cytokine. Here we demonstrate IL-33 as a regulator of functional osteoclasts (OCs) from human CD14⁺ monocytes. IL-33 stimulates formation of tartrate-resistant acid phosphatase (TRAP)⁺ multinuclear OCs from monocytes. This action was suppressed by anti-ST2 antibody, suggesting that IL-33 acts through its receptor ST2, but not by the receptor activator of NF-κB ligand (RANKL) decoy, osteoprotegerin, or anti-RANKL antibody. IL-33 stimulated activating phosphorylations of signaling molecules in monocytes that are critical for OC development. These included Syk, phospholipase Cγ2, Gab2, MAP kinases, TAK-1, and NF-κB. IL-33 also enhanced expression of OC differentiation factors including TNF-α receptor-associated factor 6 (TRAF6), nuclear factor of activated T cells cytoplasmic 1, c-Fos, c-Src, cathepsin K, and calcitonin receptor. IL-33 eventually induced bone resorption. This study suggests that the osteoclastogenic property of IL-33 is mediated through TRAF6 as well as the immunoreceptor tyrosine-based activation motif-dependent Syk/PLCγ pathway in human CD14⁺ monocytes.     

Chiral pyrrolidine-azole conjugates: Simple and efficient asymmetric organocatalysts for Michael addition to nitrostyrenes

Simple pyrrolidine-azole conjugates have been synthesized and found to be efficient catalysts for asymmetric Michael addition to nitrostyrenes. The identified optimal catalysts, pyrrolidine-azoles 2, 8 and 13, could catalyze the asymmetric Michael addition of a range of Michael donors and nitrostyrenes in high yields (up to 99%) and excellent stereoselectivities (up to 99:1 dr and 97% ee).     

流域与中国城市群空间分布规律研究

以中国(大陆)为例,把12个公认的城市群空间分布与10大河流流域空间分布叠加,结果表明两点:一是流域与城市群形成了较好的空间对应关系;二是城市群的中心城市一般在流域的最佳区位.     

‘Public’ Science: Hydrogen Balloons and Lavoisier's Decomposition of Water

The balloon mania between 1783 and 1785 put an extraordinary strain on the Paris Academy of Sciences, threatening its status as the highest tribunal of European science. Faced with repeated royal directives and public frenzy, the Academy manoeuvred carefully to steer the research toward the hydrogen balloon and thereby to maintain its scientific superiority. Antoine-Laurent Lavoisier seized this moment when the promise of ‘the empire of airs’ brought science to the centre of public attention to push his theoretical reform for chemistry. He utilized the established protocol of the Academy and the resources of the Republic of Letters to broadly publicize his first decomposition of water in April 1784. Once he attained the publicity and the balloon fever began to cool, he staged a much more elaborate experiment for the experts in February 1785. Although this second, large-scale experiment cost much expense and effort, Lavoisier never published a full account. The differential care given to the two experiments can only be understood in their divergent rhetorical contexts. The written accounts in 1784 addressed the court of public opinion, while the exclusive performance in 1785 aimed at the court of experts to inaugurate the collaborative phase of the Chemical Revolution.     

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