Robust model predictive control of continuous uncertain systems*

The authors concern robust model predictive control for linear continuous systems with polytopic uncertainties and input constraints. At each sampling time, a piecewise constant control sequence is obtained by solving a set of linear matrix inequalities. The sufficient conditions on the existence of the model predictive control are given, and the robust stability of the closed-loop systems is guaranteed. A simulation example illustrates the efficiency of the proposed method.     

Participatory Sustainability Impact Assessment: Scientific Policy Advice as a Social Learning Process

This paper deals with the development of scientific policy advice by providing a methodology to foster a social learning process. The methodology, called participatory Sustainability Impact Assessment (pSIA), aims to structure complex problem situations, to clarify interests and basic assumptions, to interpret scientific studies, to develop impact assessment, and to explore sensitivity of uncertainty and lack of information. In pSIA workshops the participants are supposed to build conceptual models with different modelling methods, like System Dynamics, Value Chain Analysis, and Morphological Analysis. A case study is presented that describes a workshop series with political as well as academic actors, applying the pSIA approach to an impact assessment of Economic Partnership Agreements between the European Union and the Eastern and Southern Africa Region.

Common variants near MC4R are associated with fat mass, weight and risk of obesity

To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the strongest association signal (rs17782313, P = 2.9 x 10(-6)) mapped 188 kb downstream of MC4R (melanocortin-4 receptor), mutations of which are the leading cause of monogenic severe childhood-onset obesity. We confirmed the BMI association in 60,352 adults (per-allele effect = 0.05 Z-score units; P = 2.8 x 10(-15)) and 5,988 children aged 7-11 (0.13 Z-score units; P = 1.5 x 10(-8)). In case-control analyses (n = 10,583), the odds for severe childhood obesity reached 1.30 (P = 8.0 x 10(-11)). Furthermore, we observed overtransmission of the risk allele to obese offspring in 660 families (P (pedigree disequilibrium test average; PDT-avg) = 2.4 x 10(-4)). The SNP location and patterns of phenotypic associations are consistent with effects mediated through altered MC4R function. Our findings establish that common variants near MC4R influence fat mass, weight and obesity risk at the population level and reinforce the need for large-scale data integration to identify variants influencing continuous biomedical traits.     

采用分块编码的小波图像压缩技术

研究了基于小波变换的图像压缩技术。在小波分解的基础上,结合人眼视觉系统（ＨＶＳ）特性,提出了一种分块编码的图像编码算法。该算法利用小波变换系数子带内和子带间的相关性以及小波系数的分布特点,有效地对高频子带数据进行了压缩。该方法实现简单,可达到很好的压缩效果。     

Study on the REM Model for Group Decision Making

IntroductionAsocialchoicefunctionisamappingwhichassignsanonemptysubsetofthepotentialfeasiblesubsettoeachorderedpairconsistentofapotentialfeasiblesubsetofalternativesandascheduleorprofileofvoters'preferences.Consideranopinionaggregationprobleminwhichagroupofexpertsgivetheirscoresthatexpresstheirpreferencestoasetofalternativesanddesiretocombinetheirscoresintoasingleaggregationpreferenceoverthealternativeset.Theunderlyingideahereisthattheconsensusofnumerousexpertsresultsinasuperiorpreferenceonthe…     

二维发汗控制方程的直线解法及其收敛性

对二维发汗控制方程建立了直线解法,可用任何解常微分方程组的数值方法求解。对固定边界（非烧蚀）和活动边界（烧蚀）情形分别进行讨论。在某些假定下给出了直线法的收敛性。     

道路施工过程中的材料消耗控制

市场经济条件下,企业的最大目的就是取得理想的经济效益,公路建设成本控制是关键,控制好影响成本主要因素的材料使用数量是公路施工企业的重要工作之一.     

浅谈城市轨道交通工程施工中450t提运架设备架梁的应用

文章针对广珠城际轨道交通工程施工中450 t提运架设备箱梁架设施工方法、工艺及技术保证措施展开论述。     

关于L-Fuzzy子集层仿紧性的注记

文[2]曾指出L－Fuzzy拓扑学中关于L－Fuzzy子集的几种仿紧性不是一般拓扑学中子集仿紧性的真正推广,即它们不以分明子集仿紧性为特款,进一步修正了几个定义并重新证明了有关的几个定理,在这篇文章中,我们拟对层仿紧性进行修正并重证相关的几个定理。     

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Atopic disease, including atopic dermatitis (eczema), allergy and asthma, has increased in frequency in recent decades and now affects approximately 20% of the population in the developed world. Twin and family studies have shown that predisposition to atopic disease is highly heritable. Although most genetic studies have focused on immunological mechanisms, a primary epithelial barrier defect has been anticipated. Filaggrin is a key protein that facilitates terminal differentiation of the epidermis and formation of the skin barrier. Here we show that two independent loss-of-function genetic variants (R510X and 2282del4) in the gene encoding filaggrin (FLG) are very strong predisposing factors for atopic dermatitis. These variants are carried by approximately 9% of people of European origin. These variants also show highly significant association with asthma occurring in the context of atopic dermatitis. This work establishes a key role for impaired skin barrier function in the development of atopic disease.