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91.
92.
This paper focuses on how to extract physically meaningful information from climate data, with em- phases placed on adaptive and local analysis. It is argued that many traditional statistical analysis methods with rigorous mathematical footing may not be efficient in extracting essential physical information from climate da- ta; rather, adaptive and local analysis methods that agree well with fundamental physical principles are more ca- pable of capturing key information of climate data. To illustrate the improved power of adaptive and local analy- sis of climate data, we also introduce briefly the empirical mode decomposition and its later developments. 相似文献
93.
David Wallace 《Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics》2009,40(3):209-222
A systematic analysis is made of the relations between the symmetries of a classical field and the symmetries of the one-particle quantum system that results from quantizing that field in regimes where interactions are weak. The results are applied to gain a greater insight into the phenomenon of antimatter. 相似文献
94.
Histidinaemic mutant in the mouse 总被引:3,自引:0,他引:3
95.
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore 总被引:1,自引:0,他引:1
Kokoszka JE Waymire KG Levy SE Sligh JE Cai J Jones DP MacGregor GR Wallace DC 《Nature》2004,427(6973):461-465
A sudden increase in permeability of the inner mitochondrial membrane, the so-called mitochondrial permeability transition, is a common feature of apoptosis and is mediated by the mitochondrial permeability transition pore (mtPTP). It is thought that the mtPTP is a protein complex formed by the voltage-dependent anion channel, members of the pro- and anti-apoptotic BAX-BCL2 protein family, cyclophilin D, and the adenine nucleotide (ADP/ATP) translocators (ANTs). The latter exchange mitochondrial ATP for cytosolic ADP and have been implicated in cell death. To investigate the role of the ANTs in the mtPTP, we genetically inactivated the two isoforms of ANT in mouse liver and analysed mtPTP activation in isolated mitochondria and the induction of cell death in hepatocytes. Mitochondria lacking ANT could still be induced to undergo permeability transition, resulting in release of cytochrome c. However, more Ca2+ than usual was required to activate the mtPTP, and the pore could no longer be regulated by ANT ligands. Moreover, hepatocytes without ANT remained competent to respond to various initiators of cell death. Therefore, ANTs are non-essential structural components of the mtPTP, although they do contribute to its regulation. 相似文献
96.
Acclimatization of soil respiration to warming in a tall grass prairie. 总被引:109,自引:0,他引:109
The latest report by the Intergovernmental Panel on Climate Change (IPCC) predicts a 1.4-5.8 degrees C average increase in the global surface temperature over the period 1990 to 2100 (ref. 1). These estimates of future warming are greater than earlier projections, which is partly due to incorporation of a positive feedback. This feedback results from further release of greenhouse gases from terrestrial ecosystems in response to climatic warming. The feedback mechanism is usually based on the assumption that observed sensitivity of soil respiration to temperature under current climate conditions would hold in a warmer climate. However, this assumption has not been carefully examined. We have therefore conducted an experiment in a tall grass prairie ecosystem in the US Great Plains to study the response of soil respiration (the sum of root and heterotrophic respiration) to artificial warming of about 2 degrees C. Our observations indicate that the temperature sensitivity of soil respiration decreases--or acclimatizes--under warming and that the acclimatization is greater at high temperatures. This acclimatization of soil respiration to warming may therefore weaken the positive feedback between the terrestrial carbon cycle and climate. 相似文献