具有4个传输零点的源-负载耦合滤波器

为了得到高选择性、小尺寸、低损耗和低成本的射频带通滤波器,提出了一种具有4个传输零点的源–负载耦合滤波器的设计方法.该滤波器采用二分之一波长T形多模谐振器,以减小滤波器尺寸和方便带宽设计.同时,根据信号的多路径传输产生零点原理,在滤波器的输入和输出端口之间加入可控耦合元件,为信号的传输提供多条路径,使得该滤波器可产生4个独立于带宽和中心频率的可控零点.文中最后设计和制作了一个带内最小测量插损为1.4dB、相对带宽为10%、具有4个传输零点的小型微带滤波器,并对其进行了测试,测试结果与仿真结果吻合良好,说明这种设计方法是有效的.     

网格化工商业市场监管系统设计与实现

介绍网格化工商市场监管系统的设计,采用分布式数据库结构,C/S与B/S相结合,实现了对企业监管的网格化、分级式管理,包括企业注册登记、企业信用等级监管、用户投诉与审核、企业荣誉与处罚等功能.     

基于C/S结构的城市公交监控系统设计

介绍了一种基于C/S结构的城市公交车监控系统,阐述了在Delphi编程环境下如何利用socket编程机制实现客户端与服务器的数据交换,实现了城市公交监控系统的设计。     

Phase field simulation of the 180° domain-switching process in PbTiO<Subscript>3</Subscript> single crystal under an antiparallel electric field

The process of 180° domain switching in PbTiO₃ single crystal under an antiparallel electric field was investigated by the three-dimensional phase field simulation, especially the effect of electric field on the type and duration of domain switching. It is found that the polarization reversal of domains takes place under an antiparallel electric field in PbTiO₃ single crystal. The results of the phase field simulation indicate that there is only 90° domain switching under a weak electric field. With the rise of the electric field, 180° domain switching appears. If the electric field is strengthened further, 90° domain switching disappears and the duration of domain switching is shortened.     

基于长短时记忆神经网络的抽油机井故障智能预警

准确预测抽油机井故障对油田生产具有重要意义。针对新疆油田某区块抽油机井故障情况,统计了500口油井的生产数据,明确了结垢、结蜡、杆管腐蚀、杆管疲劳、杆管偏磨5种引发抽油机井故障的主要因素;基于长短时记忆神经网络(long short-term memory networks, LSTM),构建了油井故障智能预警模型;筛选出影响油井故障的14种特征参数进行小波降噪处理,借助自适应矩估计算法对模型进行训练与测试。研究结果表明,模型预测准确率为96.81%,能够为油田提供较为准确的抽油机井故障预警信息。     

机匣开槽控制喷水推进器不稳定流动的数值研究

针对喷水推进器小流量工况下的驼峰区不稳定流动,采用计算流体力学方法研究了其失稳特性。结果表明,随着流量的减少,推进泵的扬程和效率显著下降,扬程曲线在0.42Q_d～0.8Q_d范围内呈现出正斜率的驼峰特性,同时内部流场变得紊乱,并出现流动分离和回流等现象。为了改善这一不稳定流动,采用了机匣开槽技术进行流动控制,使驼峰现象得到明显改善。在最佳槽体结构参数下,深度失速工况点的扬程和效率分别比原模型提高了约147.6% 和 70.3%。机匣开槽一方面能够对进口来流进行整流,起到减少预旋和增大轴向进流速度的作用,另一方面可以抑制主流区漩涡的形成以及叶轮进口位置的低频压力脉动。     

Effects of AlN on the densification and mechanical properties of pressureless-sintered SiC ceramics

In the present work, Si C ceramics was fabricated with Al N using B_4 C and C as sintering aids by a solid-state pressureless-sintered method. The effects of Al N contents on the densification, mechanical properties, phase compositions, and microstructure evolutions of as-obtained Si C ceramics were thoroughly investigated. Al N was found to promote further densification of the Si C ceramics due to its evaporation over 1800 °C,transportation, and solidification in the pores resulted from Si C grain coarsening. The highest relative density of 99.65% was achieved for Si C sample with 15.0 wt% Al N by the pressureless-sintered method at 2130 °C for 1 h in Ar atmosphere. Furthermore, the fracture mechanism for Si C ceramics containing Al N tended to transfer from single transgranular fracture mode to both transgranular fracture and intergranular fracture modes when the sample with 30.0 wt% Al N sintered at 1900 °C for 1 h in Ar. Also, Si C ceramics with 30.0 wt% Al N exhibited the highest fracture toughness of 5.23 MPa m~(1/2) when sintered at 1900 °C.     

PTC124 targets genetic disorders caused by nonsense mutations

Nonsense mutations promote premature translational termination and cause anywhere from 5-70% of the individual cases of most inherited diseases. Studies on nonsense-mediated cystic fibrosis have indicated that boosting specific protein synthesis from <1% to as little as 5% of normal levels may greatly reduce the severity or eliminate the principal manifestations of disease. To address the need for a drug capable of suppressing premature termination, we identified PTC124-a new chemical entity that selectively induces ribosomal readthrough of premature but not normal termination codons. PTC124 activity, optimized using nonsense-containing reporters, promoted dystrophin production in primary muscle cells from humans and mdx mice expressing dystrophin nonsense alleles, and rescued striated muscle function in mdx mice within 2-8 weeks of drug exposure. PTC124 was well tolerated in animals at plasma exposures substantially in excess of those required for nonsense suppression. The selectivity of PTC124 for premature termination codons, its well characterized activity profile, oral bioavailability and pharmacological properties indicate that this drug may have broad clinical potential for the treatment of a large group of genetic disorders with limited or no therapeutic options.     

微束X射线荧光分析谱仪及其对松针中元素的分布分析

介绍了一种小型的微束X射线荧光分析谱仪,它是由导管X光透镜和能量色散X射线荧光分析谱仪组成.谱仪具有较高的空间分辨率和能量分辨率.使用本谱仪对松树针叶进行了微区分析,得出各种元素沿松针长度方向和横切面径向的分布规律.结果表明使用X光透镜的微束X射线荧光分析方法可以实现植物样品的微区分析,有助于进一步了解植物的生长与元素迁移的关系.