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81.
卢武星 《北京师范大学学报(自然科学版)》1994,(4)
1.0MeV208Pb离子在非晶Si中的投影射程RP和射程偏差ΔRP作为注量和温度二者的函数用背散射法进行测定.注量的变化范围为5×1013~7×1014cm-2.注入是在室温和t=-120℃下完成的.由由实验所确定的投影射程,射程偏差与注量或温度无关,并且分别等于295和72.2nm.与TRIM86的计算结果相比较,发现RP的偏离为18%,而ΔRP的偏离为36%.RP和ΔRP二者与注量及温度的无关性,排除了所观察到的与TRIM的矛盾是由于注入期间辐射增强扩散或离子束混合效应而引起的解释。 相似文献
82.
83.
1 .INTRODUCTIONDuetotheireconomicsignificanceandclosenesstopersons,productionsystemsmustbemodeledbeforetheirimplementationanduse,thus,amethodwhichspecifies ,analyzesandsynthesizestheproductionsys tems—discreteeventsystems (DES)hasbeenestab lishedanddevelopedstepbystepinrecentyears.DESmethodspecifiestheplantbasedonitsdiscretecharacters,however,intherealworld ,therearefewplantsthatcanbemodeledbypurelydiscretemathe maticalmodelbecausetherearealwayssomecontinu ousparametersforstudyinnearlya… 相似文献
84.
Aspirin-like drugs may block pain independently of prostaglandin synthesis inhibition 总被引:2,自引:0,他引:2
K. Brune W. S. Beck G. Geisslinger S. Menzel-Soglowek B. M. Peskar B. A. Peskar 《Cellular and molecular life sciences : CMLS》1991,47(3):257-261
Summary Using flurbiprofen, a chiral anti-inflammatory and analgesic 2-arylpropionic acid derivative, the enantiomers of which are not converted to each other (less than 5%) in rats or man, we obtained evidence that prostaglandin synthesis inhibition is primarily mediating the anti-inflammatory activity but prostaglandin synthesis independent mechanisms contribute to the analgesic effects. Thus, the S-form inhibited prostaglandin synthesis, inflammation and nociception in rats. The R-form had much less effect on prostaglandin synthesis and did not affect inflammation. It did, however, block nociception in rats almost as potently as the S-form. S-flurbiprofen, in contrast to the R-form, was clearly ulcerogenic in the gastrointestinal mucosa. These results indicate additional molecular mechanisms of analgesia and suggest the use of R-arylpropionic acids as analgesics. 相似文献
85.
金属间化合物Ni3Al中的硼晶界偏聚特性的AES研究 总被引:1,自引:0,他引:1
本文应用俄歇能谱仪研究了不同化学计量比NiAl金属间化合物硼在晶界偏聚的特性。研究结果表明:硼在Ni3Al的各个晶界偏聚存在着不均匀性,硼在晶界的偏聚范围只有几个原子层,晶界结构及晶界化学环境是影响在晶界偏聚的决定因素。 相似文献
86.
张临 《科技情报开发与经济》2004,14(7):302-303
摘要:阐述了焦炭整粒在高炉冶炼中的必要性和重要性。针对临钢双齿辊切焦机的缺点进行了改造,研制出了CQD-80型齿圈式切焦机,介绍了CQD-80型齿圈式切焦机设备构造及改进,CQD-80型切焦机使用情况说明,其性能安全可靠,效果显著。 相似文献
87.
We develop in this paper an efficient way to select the best subset threshold autoregressive model. The proposed method uses a stochastic search idea. Differing from most conventional approaches, our method does not require us to fix the delay or the threshold parameters in advance. By adopting the Markov chain Monte Carlo techniques, we can identify the best subset model from a very large of number of possible models, and at the same time estimate the unknown parameters. A simulation experiment shows that the method is very effective. In its application to the US unemployment rate, the stochastic search method successfully selects lag one as the time delay and five best models from more than 4000 choices. Copyright © 2003 John Wiley & Sons, Ltd. 相似文献
88.
M E MacDonald A Novelletto C Lin D Tagle G Barnes G Bates S Taylor B Allitto M Altherr R Myers 《Nature genetics》1992,1(2):99-103
Analysis of 78 Huntington's disease (HD) chromosomes with multi-allele markers revealed 26 different haplotypes, suggesting a variety of independent HD mutations. The most frequent haplotype, accounting for about one third of disease chromosomes, suggests that the disease gene is between D4S182 and D4S180. However, the paucity of an expected class of chromosomes that can be related to this major haplotype by assuming single crossovers may reflect the operation of other mechanisms in creating haplotype diversity. Some of these mechanisms sustain alternative scenarios that do not require a multiple mutational origin for HD and/or its positioning between D4S182 and D4S180. 相似文献
89.
林建华 《华侨大学学报(自然科学版)》1992,13(1):85-91
本文利用方块脉冲函数优良的运算性质,提出一种结构动力分析简易的直接积分法——方块脉冲函数法,具有无条件稳定的积分格式,并表明方法的可行和有效. 相似文献
90.
Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp. strain RC607 总被引:10,自引:0,他引:10
Several hundred million tons of toxic mercurials are dispersed in the biosphere. Microbes can detoxify organo-mercurials and mercury salts through sequential action of two enzymes, organomercury lyase and mercuric ion reductase (MerA). The latter, a homodimer with homology to the FAD-dependent disulphide oxidoreductases, catalyses the reaction NADPH + Hg(II)----NADP+ + H+ + Hg(0), one of the very rare enzymic reactions with metal substrates. Human glutathione reductase serves as a reference molecule for FAD-dependent disulphide reductases and between its primary structure and that of MerA from Tn501 (Pseudomonas), Tn21 (Shigella), p1258 (Staphylococcus) and Bacillus, 25-30% of the residues have been conserved. All MerAs have a C-terminal extension about 15 residues long but have very varied N termini. Although the enzyme from Streptomyces lividans has no addition, from Pseudomonas aeruginosa Tn501 and Bacillus sp. strain RC607 it has one and two copies respectively of a domain of 80-85 residues, highly homologous to MerP, the periplasmic component of proteins encoded by the mer operon. These domains can be proteolytically cleaved off without changing the catalytic efficiency. We report here the crystal structure of MerA from the Gram-positive bacterium Bacillus sp. strain RC607. Analysis of its complexes with nicotinamide dinucleotide substrates and the inhibitor Cd(II) reveals how limited structural changes enable an enzyme to accept as substrate what used to be a dangerous inhibitor. Knowledge of the mode of mercury ligation is a prerequisite for understanding this unique detoxification mechanism. 相似文献