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871.
Whole-genome duplication followed by massive gene loss and specialization has long been postulated as a powerful mechanism of evolutionary innovation. Recently, it has become possible to test this notion by searching complete genome sequence for signs of ancient duplication. Here, we show that the yeast Saccharomyces cerevisiae arose from ancient whole-genome duplication, by sequencing and analysing Kluyveromyces waltii, a related yeast species that diverged before the duplication. The two genomes are related by a 1:2 mapping, with each region of K. waltii corresponding to two regions of S. cerevisiae, as expected for whole-genome duplication. This resolves the long-standing controversy on the ancestry of the yeast genome, and makes it possible to study the fate of duplicated genes directly. Strikingly, 95% of cases of accelerated evolution involve only one member of a gene pair, providing strong support for a specific model of evolution, and allowing us to distinguish ancestral and derived functions. 相似文献
872.
Holocene lake deposits of Bosten Lake, southern Xinjiang, China 总被引:9,自引:0,他引:9
B.Wünnemann 《科学通报(英文版)》2003,48(14):1429-1432
A 9.25-m-long sediment core from Bosten Lake,Xinjiang, provides detailed information about changes in the water budget and biological acticity over the last 8400 cal-endar years. The chronology is constructed from six AMS radiocarbon dates on the terrestrial plant remains. Based onanalyses of TOC, CO3, detrital compounds and biogenic SiO2,lake level fluctuations and periods of remarkably-negative water budget appeared at 8.4-8.2 cal ka, 7.38-7.25 cal ka,5.7-5.5 cal ka, 3.7-3.4 cal ka and 3.3-2.9 cal ka, respec-tively. As they are in-phase with low lake levels at Sumxl Co and Bangong Co in western Tibet Plateau and with paleo-lakes in Inner Mongolia, a climate-induced change to some-what drier and warmer conditions is inferred. A further drop in lake level after 1320 AD of about 200 yr duration may heattributed to a negative water balance prior to the main phase of the Little Ice Age. Deep and stable lake phases of 1500 yr and 1800 yr duration at 7.2-5.7 cal ka and 5.5-3.7cal ka coincide with maximum moisture during the Holocene Megathermai in China. The long term trend towards aridity since about 4.3 cal ka can dearly be recognised. The reduced water budget of Bosten Lake from 640-1200 AD may be attributed to local effects. 相似文献
873.
Kang HJ Dai P Lynn JW Matsuura M Thompson JR Zhang SC Argyriou DN Onose Y Tokura Y 《Nature》2003,423(6939):522-525
Superconductivity in the high-transition-temperature (high-T(c)) copper oxides competes with other possible ground states. The physical explanation for superconductivity can be constrained by determining the nature of the closest competing ground state, and establishing if that state is universal among the high-T(c) materials. Antiferromagnetism has been theoretically predicted to be the competing ground state. A competing ground state is revealed when superconductivity is destroyed by the application of a magnetic field, and antiferromagnetism has been observed in hole-doped materials under the influence of modest fields. None of the previous experiments have revealed the quantum phase transition from the superconducting state to the antiferromagnetic state, because they failed to reach the upper critical field B(c2). Here we report the results of transport and neutron-scattering experiments on electron-doped Nd1.85Ce0.15CuO4 (refs 13, 14), where B(c2) can be reached. The applied field reveals a static, commensurate, anomalously conducting long-range ordered antiferromagnetic state, in which the induced moment scales approximately linearly with the field strength until it saturates at B(c2). This and previous experiments on the hole-doped materials therefore establishes antiferromagnetic order as a competing ground state in the high-T(c) copper oxide materials, irrespective of electron or hole doping. 相似文献
874.
Pang Xin-an Wang Qing-fengf Gituru W. Robert Liu Hong Yang Xiao-lin Liu Xing 《武汉大学学报:自然科学英文版》2003,8(2):455-458
Isoetes sinensis Palmer (Isoetaceae) is an aquatic or amphibious plant that is critically endangered in China. Previous studies have revealed
the crassulacean acid metabolism (CAM)-like photosynthetic pathway occurs commonly in submerged leaves in genusIsoetes. Water chemistry parameters and the titratable acidity content of the plant extract were measured from samples obtained in
the early morning (7∶00) and late afternoon (15∶00) from twoI. sinensis populations in China. One population occurs in the eulittoral zone of a freshwater tidal river at low elevation (134 m) and
another occurs in a densely vegetated, high elevation (1 100 m) alpine shallow pool. Significant differences in pH and titratable
acidity of the plant extract were detected between the morning and afternoon samples. These changes are associated with diurnal
changes in water chemistry. Our results provide the first evidence for the existence of the CAM pathway in the East Asian
endemicIsoetes sinensis Palmer. The magnitude of fluctuations in the titratable acidity of the plant extract may be correlated with the severe carbon
limitation imposed on the plants by its aquatic habitat.
Foundation item: Supported by the State Key Basic Research and Development Plan (G2000046805)
Biography:Pang Xin-an (1974-), male, Master candidate, research direction: conservation biology. 相似文献
875.
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879.
CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1. 总被引:12,自引:0,他引:12
THE protein CD43 (also known as sialophorin, leukosialin, large sialoglycoprotein or gp115) is expressed on the surface of T lymphocytes, monocytes, neutrophils, platelets and some B lymphocytes. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome, suggesting that CD43 might have a role in T-cell activation. We have shown that expression of human CD43 in an HLA-DR-specific murine T-cell hybridoma enhances the antigen-specific response to stimulation by the human lymphoblastoid cell line Daudi, and that Daudi cells bind specifically to purified immobilized CD43. These data indicate that the specific interaction of CD43 with a ligand on the surface of Daudi cells might contribute to T-cell activation. Here we report evidence that intercellular adhesion molecule-1 (ICAM-1, or CD54), is a ligand for CD43. 相似文献
880.
Levamisole inactive in treatment of four animal tumours 总被引:3,自引:0,他引:3