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21.
A. V. Edwards M. A. Ghatei S. R. Bloom 《Cellular and molecular life sciences : CMLS》1994,50(8):725-726
Mean plasma insulin concentration was reduced and mean plasma glucose concentration increased following the administration of N-nitro-L-arginine methyl ester (L-NAME; 100 mol kg–1 i.a.) in conscious calves given continuous infusions of exogenous glucose (30–60 mol min–1 kg–1 i.v.). It is concluded that the rise in plasma insulin concentration which occurs in these animals in response to glucose is mediated, at least in part, by a nitric oxide-related factor (NOx). 相似文献
22.
23.
S. F. Wang J. C. Braekman D. Daloze J. Pasteels P. Soetens N. V. Handjieva P. Kalushkov 《Cellular and molecular life sciences : CMLS》1996,52(6):628-630
The isolation of N-quinaldyl-L-arginine·HCl (1) from the CoccinellidaeSubcoccinella-24-punctata is reported. The structure, first established on the basis of the analysis of the spectral properties of1, has been confirmed by synthesis. The alkaloid is of endogenous origin and markedly deterrent to ants. 相似文献
24.
Molecular evidence for increased hematopoietic proliferation in the spleen of the b/b laboratory rat
S. Savković S. Pavlović T. Mitrović M. Joksimović J. Marjanović V. Glišin Z. Popović 《Cellular and molecular life sciences : CMLS》1996,52(8):807-811
The splenomegaly and the appearance of a significant number of CFU-E (erythroid colony-forming units) and BFU-E1 (erythroid burst-forming units) in the Belgrade laboratory rat (b/b) spleen prompted us to analyse further the molecular evidence for increased hematopoietic proliferation in the b/b spleen. Messenger RNAs (mRNAs) specific for globins, proteins for iron transport and deposition and the band 3 protein were used in rat erythropoietic tissues as markers for proliferation and erythroid differentiation. In the b/b spleen, all mRNAs analysed display an erythroid-specific pattern of expression. This analysis also revealed an enhanced level of mRNA for ferritin in the +/b spleen, whereas erythrocyte-specific mRNA production was normal. 相似文献
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26.
F. V. DeFeudis L. M. Orensanz Muñoz M. A. Vidal G. Corrochano M. Sanchez del Alamo 《Cellular and molecular life sciences : CMLS》1978,34(9):1169-1170
Summary High-affinity, Na+-independent binding of -alanine to a synaptosomal fraction of rat brain was potently inhibited by glycine and by some other -amino acids, but not by taurine or GABA. This binding mechanism, which was also sensitive to both bicuculline and strychnine, might involve synaptic receptors for both -alanine and glycine.This study was supported in part by Centro Ramón y Cajal and Fundacion Juan March. 相似文献
27.
T. T. Yen J. A. Allan D. V. Pearson J. M. Acton 《Cellular and molecular life sciences : CMLS》1978,34(12):1542-1543
Summary Treating VY/WfL-A
vy
/a mice with 5-androstan-17-one, a mammalian glucose-6-phosphate dehydrogenase inhibitor, prevented the mice from becoming obese. The weight difference between treated and controlA
vy
/a mice was mainly due to a decreased accumulation of triacylglycerol. The compound did not suppress appetite, had no detectable toxicity and did not affect the lipogenesis rates in the liver and carcass. The weight-controlling effect of 5-androstan-17-one inA
vy
/a mice was reversible upon withdrawal of treatment.The authors wish to thank Mr W.R. Gibson and Drs C.G. Culbertson and P.N. Harris for performing the pathological examinations. 相似文献
28.
N. Michajlovskij V. Štrbák O. Földes 《Cellular and molecular life sciences : CMLS》1978,34(3):409-410
Summary The administration of thiocyanate to rats caused a significant increase of serum free thyroxine fraction, which coincided with the significant decrease of TSH level. The other components (AFT4, T4, T3) in serum at this time were decreased or unchanged. The finding suggests the role of free thyroxine fraction in feed-back regulation of TSH secretion.Acknowledgment. We thank Dr A. Parlow and the NIAMDD, Rat Pituitary Hormone Distribution Program, for material for rat TSH immunoassay; Dr J. Nauman (Inst. Postgrad. Med., Warsaw, Poland) for T3 antibody, and to Ing. J. Sadlo, Mrs M. t'astná and Miss R Fajkoová for technical assistance. 相似文献
29.
Summary The seedling growth ofBrassica campestris var.varuna, has been studied, as affected by water-stress and gibberellin treatments. A boost in the net GA response due to water-stress, has been observed. Thus presence of GA can overcome the water-stress effects.Publication No. 26 from Dept of Biosciences, Himachal Pradesh University, Simla. Authors are grateful to CSIR, New Delhi, for JRF to SB. 相似文献
30.
Summary The effects of time and various doses of testosterone on the responsiveness of lactate dehydrogenase of pituitary of 7-, 38- and 78-week-old rats were studied. The activity of the enzyme increases in 78-week-old rats. Castration decreases the enzyme activity at all ages. Maximum increase in the enzyme activity is seen with 50 and 100 g of testosterone 4 h after administration of hormone to castrated rats. No further time and dose-dependent effect is observed. The magnitude of increase for the enzyme is higher at the age of 38 weeks and decreases in 78-week-old rats.To whom all correspondence should be addressed. The authors are grateful to Professor M.S. Kanungo, Biochemistry Laboratory, Department of Zoology, Banaras Hindu University for the suggestions and encouragement. K.V.G. thanks the PL-480 for a research fellowship. 相似文献