板材折弯弯曲工序的计算机辅助自动生成

利用基于特征信息建模生成零件的设计模型，通过加工特征自动提取和制造决策知识规纳，运用知识Ｐｅｔｒｉ网建模，开发了板材折弯计算机辅助工艺规划系统。该系统根据输入的零件图形自动生成折弯工序，并在计算机上进行仿真，成为ＣＡＤ和ＣＡＭ之间联系的纽带。     

适应于伽辽金方法的梁本征函数及其应用

利用克雷洛夫函数的组合，构造了三个满足不同边界约束条件的梁本征函数，并通过伽辽金方法，用它们逼近不同载荷具有铰支、固支任意组合的梁、板的挠曲线、挠曲面。计算结果表明，三个梁本征函数收敛迅速。在梁和板挠曲变形中，级数分别取头２，３项，便可得到相当满意的结果，其相对误差可控制在１％左右。给出的梁本征函数可以用于求解更为复杂的梁、板、壳结构。     

用稳燃腔煤粉燃烧器提高劣质煤稳燃性研究

在分析韶关电厂５＃炉燃煤特性的基础上，进行了采用稳燃腔煤粉燃烧器提高劣质煤燃烧稳定性的研究。试验结果表明，该燃烧器对劣质煤具有很强的稳燃效果。     

进给箱传动方案设计的智能CAD

综合运用人工智能理论及专家系统与现代ＣＡＤ技术，成功地开发了龙门铣床进给箱传动方案设计智能ＣＡＤ系统ＦＢＳＩＣＡＤ．通过对传动方案设计的分析，提出了系统设计的基本原则和方法，并给出了该系统的控制结构与功能。     

掺入轻稀土元素对薄膜的磁光克尔效应的增强

从磁光克尔效应的宏观唯象理论和量子理论出发分析了轻稀土元素对磁光克尔效应的增强机理；研究了轻稀土元素ＬＲＥ（Ｎｄ，Ｓｍ，Ｐｒ）掺入后（ＬＲＥ，ＨＲＥ）－ＴＭ薄膜的稀上成分比和溅射时基片负偏压对薄膜磁光克尔角的影响，研究结果表明，轻稀土元素的掺入能使ＨＲＥ－ＴＭ磁光薄膜的磁光克尔效应得到明显的增强。     

一种工业用内窥镜摄影系统

给出一种新型的工业用内窥镜摄影系统，该系统由内窥镜、光学关节（四节刚性转像透镜导管）、摄影联接管和摄影机四部分组成。它可将图像传到高速摄影机拍摄和记录各种动态过程，也可用ＣＣＤ摄像机接收信息送计算机处理，以进行工业检测。给出了内窥镜摄影系统的基本原理、设计要点和实验结果。     

一类非线性发展方程解的渐近性态

利用Ｂａｎａｃｈ空间几何特征理论，讨论了Ｂａｎａｃｈ空间中一类与非线性Ｖｏｌｔｅｒｒａ型积分方程有关的非线性发展方程解的渐近性态，并分别给出了此类方程的强解在无穷远处弱收敛与强收敛的收敛条件以及收敛结果，从而推广了已有的结论。     

A precision measurement of the mass of the top quark

The standard model of particle physics contains parameters--such as particle masses--whose origins are still unknown and which cannot be predicted, but whose values are constrained through their interactions. In particular, the masses of the top quark (M(t)) and W boson (M(W)) constrain the mass of the long-hypothesized, but thus far not observed, Higgs boson. A precise measurement of M(t) can therefore indicate where to look for the Higgs, and indeed whether the hypothesis of a standard model Higgs is consistent with experimental data. As top quarks are produced in pairs and decay in only about 10(-24) s into various final states, reconstructing their masses from their decay products is very challenging. Here we report a technique that extracts more information from each top-quark event and yields a greatly improved precision (of +/- 5.3 GeV/c2) when compared to previous measurements. When our new result is combined with our published measurement in a complementary decay mode and with the only other measurements available, the new world average for M(t) becomes 178.0 +/- 4.3 GeV/c2. As a result, the most likely Higgs mass increases from the experimentally excluded value of 96 to 117 GeV/c2, which is beyond current experimental sensitivity. The upper limit on the Higgs mass at the 95% confidence level is raised from 219 to 251 GeV/c2.     

Sequential proteome alterations during genesis and progression of colon cancer

Changes in the proteome of colon mucosal cells accompany the transition from normal mucosa via adenoma and invasive cancer to metastatic disease. Samples from 15 patients with sporadic sigmoid cancers were analyzed. Proteins were separated by two-dimensional gel electrophoresis. Relative differences in expression levels between normal tissue, adenoma, carcinoma and metastasis were evaluated in both intra- and inter-patient comparisons. Up- and down-regulated proteins (<twofold) during development to cancer or metastasis were excised and submitted to peptide mass fingerprinting and MS/MS sequence analysis, facilitated by the use of a compact disc workstation. In total, 112 protein spots were found to be differentially regulated, of which 72 were determined as to protein identity, 46 being up-regulated toward the progression of cancer, and 26 down-regulated. Several of the identifications correlate with proteins of the cell cycle, cytoskeleton or metabolic pathways. The pattern changes now identified have the potential for design of marker panels for assistance in diagnostics and therapeutic strategies in colorectal cancer.Received 2 February 2004; received after revision 16 March 2004; accepted 18 March 2004     

Antifungal proteins: targets,mechanisms and prospective applications

All organisms have evolved several defence systems in order to protect themselves against bacteria, fungi and viruses. Higher organisms have developed a complex network of humoral and cellular responses, called adaptive immunity. A second defence system, innate immunity, was discovered in the early 1980s, consisting of small cationic peptides with a broad antimicrobial spectrum. These proteins act immediately at sites of infection or inflammation. The production of proteins with antimicrobial activity was not limited to higher organisms but was also found in insects, plants and microorganisms. During the last 2decades a broad range of proteins with very different structural features have been isolated and characterised from differing organisms ranging from bacteria to human beings. Over 500cationic membrane-acting proteins with antimicrobial and antifungal activities have been identified to date. Apart from these proteins, a very large number of antifungal proteins active on the fungal cell wall, on enzymes of the cell wall synthesis machinery, the plasma membrane and on intracellular targets have been characterised.Received 17 June 2003; received after revision 4 August 2003; accepted 18 August 2003