On the Distribution of Prime-Triplets

A new approach to the research of the distribution of prime-triplets is developed．It differs from the usual methods（involving the sieve method）for this kind of research,and basing on Chebyshev inequality and on the computation of average concentration of all the related subset．It leads to the proofs of following Lemma ２and Theorem２（Lemma１and Theorem１in Reference１had been proved by means of this new method）： 　Lemma２　Among all the prime-triplet-subsets there exists at least one such subset which is an infinite set． 　Theorem２　All the prime-triplet-subsets or infinitely many such subsets are infinite sets． Formulas for estimating the amount of such infinite sets are provided in this paper．     

基于至少满足弱硬实时限制的调度算法

提出了一种用于保证实时周期任务满足“至少满足”弱硬实时限制的算法.针对以往算法的缺点,扩充了弱硬实时限制的性质,定义了下确界限制并给出求解法.下确界限制用于保证任务满足“至少满足”弱硬实时限制,是任务满足限制的下确界.下确界限制的求解法计算负责度较低,因此在该求解法的基础上设计了调度算法MAA,用于保证任务满足“至少满足”弱硬实时限制.     

Lysosomal chymotrypsin B potentiates apoptosis via cleavage of Bid

We have reported that chymotrypsin B (CtrB) is not just a digestive enzyme but is also stored in lysosomes. Herein, we demonstrated a broad distribution of CtrB and explored the involvement of CtrB in apoptosis. Exposure of RH-35 cells to H₂O₂ or palmitate induced the redistribution of lysosomal CtrB into the cytoplasm as a result of lysosomal membrane permeabilization (LMP). Suppression of CtrB significantly blocked apoptosis, while overexpression of CtrB sensitized apoptosis markedly. CtrB could cleave Bid under neutral conditions. In RH-35 cells with Bid silenced, apoptosis induced by CtrB protein was attenuated, suggesting that CtrB mediates apoptosis of RH-35 cells mainly through processing Bid. Our data also suggest that LMP occurs earlier than mitochondrial outer membrane permeabilization; Bid activation initiated by caspase-8 might be reinforced by CtrB in consequence of LMP, which causes a positive feedback loop leading to the accumulation of tBid, and results in lysosome- and mitochondrion-dependent apoptosis.     

打造孝感“大十字”区域快速公交网络,促进城乡一体化发展

公交系统建设反映一个城市的综合发展水平和文明程度,同时也是其经济社会发展的重要基础.湖北孝感地处武汉城市圈的核心层,但公共交通建设滞后,一直存在起步晚、线路密度低、服务质量不高、连接城乡线路欠缺等问题,严重制约城市品位提升,社会要素流动,进而影响孝感经济社会发展.结合孝感总体城市发展战略,必须着眼于构建基于云梦——孝感——天河与孝昌——孝感——东西湖的大十字公共交通网络,推动孝感城乡一体化发展,加快与大武汉对接融合,打造武汉城市圈核心层新增长极.     

Effect of protein molecules on the photoluminescence properties and stability of water-soluble CdSe/ZnS core-shell quantum dots

The fact that the photoluminescence properties of quantum dots are always strongly influenced by the environment limits the scope of further progress in the field of QD’ bio-applications. In this paper, the effects of immunoglobulin G (IgG) on the photo-luminescence properties and stability of water-soluble CdSe/ZnS core-shell quantum dots coated with amphiphilic poly (acrylic acid) (PAA) are studied. Photoluminescence (PL) spectra, UV-vis spectra and excited state lifetime measurements are used to characterize the influence of different protein molecules, such as IgG (goat anti-human IgG, rabbit anti-human IgG, human IgG, and goat anti-human IgG-human IgG conjugates), avidin and bovine serum albumin (BSA) on the PL properties of QDs. The PL intensity and stability of CdSe/ZnS are largely enhanced compared to that of pure CdSe/ZnS QDs when the IgG molecules are added into the QD solution. The PL intensity increases with increasing the IgG concentration, but there appears no influence on the PL peak and a full width at half maximum (FWHM). The PL evolution of QDs as a function of different protein molecules depends on the structure of protein molecules, which is used as a sensor to recognize human IgG. It is inferred that the interaction between PAA coating layer and IgG molecules results in the enhancement of PL intensity. The study of the effect of pH and ion strength on optical properties of QD-IgG mixed solution, compared with the pure QD solution, suggests that pH value and ion strength do not destroy the interaction between the PAA coating layer and IgG. Excited state lifetime analysis indicates that the PL enhancement comes from the passivation of surface of the QDs with the PAA coating layer. IgG molecules have no effects on the properties of the biological system but can increase the stability and PL intensity of CdSe/ZnS QDs, which will enlarge the application of QDs in biomedicine and other fields.     

In-situ cosmogenic 36Cl denudation rates of carbonates in Guizhou karst area

This study quantifies surface denudation of carbonate rocks by the first application of in-situ cosmogenic36Cl in China. Concentrations of natural Cl and in-situ cosmogenic36Cl in bare carbonates from Guizhou karst areas were measured with isotope dilution by accelerator mass spectrometer. The Cl concentration varied from 16 to 206 ppm. The 36Cl concentrations were in range of (0.8-2.4)106 atom g-1 , resulting in total denudation rates of 20-50 mm ka-1 that averaged over a 104-105 a timescale. The 36Cl-denudation rates showed roughly a negative correlation with the local mean temperature. This preliminary observation may suggest the variations of proportions of chemical weathering and physical erosion in denudation process, depending upon local climatic conditions.     

组稿中需要注意和具备的几个问题与能力

组稿是策划编辑的一项重要工作,对选题的落实质量起着重要的影响作用.在组稿过程中需要注意什么问题,以及在组稿工作中需要编辑具备什么能力?本文对此作了简要的论述.     

枯草杆菌JAS株α—淀粉酶的产生与其抗衣霉素的关系

为了研究Bacillus subtilis的产α-淀粉酶性状与其抗衣霉素性状之间的关系,进一步选择在诱变育种时能有效地筛选淀粉酶基因突变株的方法,我们对此作了初步探索.衣霉素敏感型的α-淀粉酶工业生产菌B.subtilis JAS经过紫外线诱变后,选得9株抗衣霉素突变株.通过对它们进行的多次发酵酶活力测定,发现其中3株是α-淀粉酶缺陷型、3株酶活力基本不变或降低,另外3株酶活力明显提高,其中1株酶活力是出发菌株的114%—123%.试验表明B.subtilis α-淀粉酶的产生与其抗衣霉素基因的表达有着密切关系.因此,在对该菌的诱变育种时,可以采用衣霉素为粗筛选择压力.