An Asynchronous 32×8-Bit Multiplier Based on LDCVSPG Logic

An asynchronous high-speed pipelined 32×8-bit array multiplier based on latched differential cascode voltage switch with pass-gate (LDCVSPG) logic is presented. The multiplier is based on 4-phase dual-rail protocol. HSPICE analysis using device parameters of Central Semiconductor Manufacturing Corporation (CSMC's) 0.6 μm CMOS technology is also given, and the result shows that the average data throughput of the multiplier is 375 MHz.     

英语学习中的负迁移现象及其预防措施

从心理学的角度，浅谈英语学习中负迁移的形成及其预防措施。     

普通物理习题教学研究一例

根据学生通常存在的疑问 ,通过启发和引导学生在求解习题的过程中学会思考。     

微机控制设备部件检测技术的新思路--以产品自身资源为平台的自动检测技术

从对DISA-II设备的印制板组件的自动检测系统的分析入手,提出以产品自身软、硬件资源为平台的自动检测技术的新思路,并分析了其实用价值,介绍了设计要点.     

关于螺旋插齿刀CAD／CAM几何模型研究

针对目前螺旋插齿刀设计中存在的问题、提出设计此类刀具的一种无设计误差的新方法，给出了相应的设计与制造的几何模型，最后结合具体算例，验证了本模型的可靠性，因此，本文对提高目前刀具制造精度和产品的加工质量具有一定的实际意义。     

宜宾县金沙江圈坝河流域坡耕地治理现状与启示

通过宜宾圈坝河小流域坡改梯治理水土流失情况分析，得出金沙江流域坡改梯水土流失治理的启示，并指出存在的问题和解决办法。     

关于雷达/ARPA稳定方式的探讨

对海稳定和地稳定矢量的优点和局限性作了全面地分析，并对雷达视角在避碰中的作用提出了不同看法。为了适应雷达在避碰和导航中的需要，对正确选用矢量稳定方式阐述了作者独到见解，并对ＡＲＰＡ性能指标提出了修改意见。     

集团信息化成功建设与应用的核心要素分析——以国内某水泥集团信息化建设项目为例

以国内某水泥集团的信息化项目建设为例,探讨了集团信息化建设中的难点,从产品、人力、沟通、方法、费用5个方面分析了集团信息化建设成功的核心要素。     

MiR-205 inhibits the invasion and migration of esophageal squamous cell carcinoma by modulating SMAD1 expression

Esophageal squamous cell carcinoma （ESCC） is one of the most lethal cancers worldwide. In this study, we aimed to investigate the underlying mechanisms of metastasis inhibition by miR-205 in ESCC. In microRNA （miRNA） array and quantitative RT-PCR analyses, we found that the expression level of miR-205 was significantly lower in patients with lymph node metastasis compared with that in patients without lymph node metastasis. After transfection of miR-205 mimics or inhibitors into ESCC cell lines, a significant negative correlation was observed between the expression level of miR-205 and Smad 1. In luciferase reporter assays, we revealed that miR- 205 inhibited the expression of SMAD1 by targeting the 3＇ untranslated region （3＇-UTR） of SMAD1 mRNA in ESCC cells. Furthermore, our results showed that miR-205 sup- pressed the invasion and migration of ESCC cells, whereas Smadl increased their invasion and migration. Taken together, our study demonstrates that miR-205 functions as a suppressor of tumor metastasis by regulating SMAD1 expression through targeting the 3＇-UTR of SMAD1 mRNAin ESCC. Therefore, miR-205 may be a potential therapeutic target for miRNA-based therapy of ESCC.     

R^n中置换凸体的结构

利用极植分析研究并得到了R^n（n≥3,n∈N）中置换凸体的相关结构.