谱分析方法在经济波动分析中的应用研究

针对我国经济序列较短的特点,将加窗周期图谱估计与最大熵谱估计相结合的谱估计方法用于经济周期波动的分析,并用各隐周期分量单独分辨的办法通过对数据进行三角叠加拟合来确定隐周期长度的准确值。     

Structural basis for self-association and receptor recognition of human TRAF2

Tumour necrosis factor (TNF)-receptor-associated factors (TRAFs) form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily and the interleukin-1 receptor. They are important in the regulation of cell survival and cell death. The carboxy-terminal region of TRAFs (the TRAF domain) is required for self-association and interaction with receptors. The domain contains a predicted coiled-coil region that is followed by a highly conserved TRAF-C domain. Here we report the crystal structure of the TRAF domain of human TRAF2, both alone and in complex with a peptide from TNF receptor-2 (TNF-R2). The structures reveal a trimeric self-association of the TRAF domain, which we confirm by studies in solution. The TRAF-C domain forms a new, eight-stranded antiparallel beta-sandwich structure. The TNF-R2 peptide binds to a conserved shallow surface depression on one TRAF-C domain and does not contact the other protomers of the trimer. The nature of the interaction indicates that an SXXE motif may be a TRAF2-binding consensus sequence. The trimeric structure of the TRAF domain provides an avidity-based explanation for the dependence of TRAF recruitment on the oligomerization of the receptors by their trimeric extracellular ligands.     

高层框架—核心筒体减震结构模型试验

通过单层，三层结构模型的动力试验结果，表明在框架－核心筒体结构体系内安装减震器后，减震效果显著，试验与计算结果吻合较好，说明了计算理论的正确性。     

伯胺И_(1923)从硫代硫酸钠-亚硫酸钠介质中萃取银的研究

研究了用伯胺N_(1928)从Ha_2S_2O_3-Na_2SO_3介质中萃取银的机理.由于S_2O_3~(2-)易被氧化.因此萃取时不应有氧化性离子如NO_8~-等存在,并且要加入Na_2SO_3作稳定剂.此外,有机相伯胺的硫代硫酸盐也是临用时制备的.萃取的最适合pH在3.5～6.0.萃合物的组成用4种方法测定:即Job氏法,饱和容量法,斜率法与饱和有机相的化学分析.它们都表明萃合物组成为(RNH_3)_5Aga(S_2O_3)_4.用红外光谱研究了被萃阴离子的结构,说明该阴离子为折线状,测得该反应的热力学函数为logKex=27.05.△H°=-49.3J/mol,△G°=-141.3/kJmol与△S°=517.1J/mol·K。     

挤出机螺栓失效分析

作者通过各项测试、断口分析及有关机械设计计算,较全面地分析了螺栓的失效形式及原因,并提出防止失效的措施,从而为保证挤出机的正常运转和安全生产提供了有益的依据,也为探讨失效分析技术在机械零部件方面的应用提供有效的方法。     

Schiff碱H2TTAen,H2TTAdien,H2TTApn的合成和螯合性能的研究

以ＨＴＴＡ为端基与乙二胺、二乙三胺及丙二胺缩合制得Ｈ２ＴＴＡｅｎ，Ｈ２ＴＴＡｄｉｅｎ，Ｈ２ＴＴＡＰｎ３种Ｓｃｈｉｆｆ碱．它们既类似于聚酸可作多齿螯合配体，又与ｐ－二酮类似，其羰其可以异构成烯醇式，为一个二元酸．用多种近代分析测试方法对其组成和基本性质进行了表征，用ＰＨ电位法和光度法测定了酸离解常数．     

Human sweat components — Attractancy and repellency to mosquitoes

Zusammenfassung Es wird gezeigt, dass menschliche Schweissabsonderungen verschiedener Versuchspersonen auf weibliche Moskitos (Aedes aegypti) verschieden attraktiv sind. Mit Diethyläther (pH 1) lassen sich im Schweiss sowohl «anlockende» wie auch «abschreckende» Bestandteile extrahieren. Für den «repellent effect» sind teilweise gleiche Mischungen von Milchsäure und Milchsäureanhydrid verantwortlich. Zwei weitere, noch nicht identifizierte Substanzen zeigten im Zwei-Kammer-Olfaktometer identische «repellent» Wirkungen.

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This study was supported by U.S. Army Medical Research and Development Command, Dept. of the Army, Contracts No. DA 49-193-MD-2465 (W. Skinner) and No. DA 49-193-MD-2466 (H. Maibach). We thank Dr.L. Pope, Superintendent, and the inmates of the California Medical Faculty, Vacaville, California, USA, for their cooperation in this study.     

Evidence for dynamically organized modularity in the yeast protein-protein interaction network

In apparently scale-free protein-protein interaction networks, or 'interactome' networks, most proteins interact with few partners, whereas a small but significant proportion of proteins, the 'hubs', interact with many partners. Both biological and non-biological scale-free networks are particularly resistant to random node removal but are extremely sensitive to the targeted removal of hubs. A link between the potential scale-free topology of interactome networks and genetic robustness seems to exist, because knockouts of yeast genes encoding hubs are approximately threefold more likely to confer lethality than those of non-hubs. Here we investigate how hubs might contribute to robustness and other cellular properties for protein-protein interactions dynamically regulated both in time and in space. We uncovered two types of hub: 'party' hubs, which interact with most of their partners simultaneously, and 'date' hubs, which bind their different partners at different times or locations. Both in silico studies of network connectivity and genetic interactions described in vivo support a model of organized modularity in which date hubs organize the proteome, connecting biological processes--or modules--to each other, whereas party hubs function inside modules.