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171.
Jaffe W Meisenheimer K Röttgering HJ Leinert Ch Richichi A Chesneau O Fraix-Burnet D Glazenborg-Kluttig A Granato GL Graser U Heijligers B Köhler R Malbet F Miley GK Paresce F Pel JW Perrin G Przygodda F Schoeller M Sol H Waters LB Weigelt G Woillez J De Zeeuw PT 《Nature》2004,429(6987):47-49
Active galactic nuclei (AGNs) display many energetic phenomena--broad emission lines, X-rays, relativistic jets, radio lobes--originating from matter falling onto a supermassive black hole. It is widely accepted that orientation effects play a major role in explaining the observational appearance of AGNs. Seen from certain directions, circum-nuclear dust clouds would block our view of the central powerhouse. Indirect evidence suggests that the dust clouds form a parsec-sized torus-shaped distribution. This explanation, however, remains unproved, as even the largest telescopes have not been able to resolve the dust structures. Here we report interferometric mid-infrared observations that spatially resolve these structures in the galaxy NGC 1068. The observations reveal warm (320 K) dust in a structure 2.1 parsec thick and 3.4 parsec in diameter, surrounding a smaller hot structure. As such a configuration of dust clouds would collapse in a time much shorter than the active phase of the AGN, this observation requires a continual input of kinetic energy to the cloud system from a source coexistent with the AGN. 相似文献
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The importance of extracellular sodium and potassium for acetylcholine-evoked salivary secretion 总被引:1,自引:0,他引:1
O H Petersen 《Experientia》1970,26(10):1103-1104
175.
A. O. Vladutiu 《Cellular and molecular life sciences : CMLS》1981,37(7):778-780
Summary All previous attempts failed to induce thyroglobulin antibodies or thyroid infiltrates in mice immunized with homologous thyroglobulin without adjuvants. However, an allogeneic effect obviated the need of adjuvants for triggering thyroglobulin-reactive lymphocytes to produce thyroglobulin antibodies or thyroid lesions.This work was supported by a grant from the Margaret Duffy and Robert Cameron C. Troup Fund. I thank Ellen Kenney for technical assistance and Dr Pei-nan Tsung for the X-ray irradiation. 相似文献
176.
Riassunto La stimolazione a 3–8/sec di nervi cutanei e muscolari, eseguita in gatti integri non anestetizzati, produce una sincronizzazione dell'attività elettrica cerebrale. La soglia per questa risposta corrisponde in media a 0,4–0,9 volte l'intensità minima di corrente che applicata allo stesso nervo e in analoghe condizioni sperimentali produce la reazione di risveglio.
This investigation was supported by PHS research grant B-2990 from the National Institute of Neurological Diseases and Blindness, N.I.H., Public Health Services, U.S.A. 相似文献
This investigation was supported by PHS research grant B-2990 from the National Institute of Neurological Diseases and Blindness, N.I.H., Public Health Services, U.S.A. 相似文献
177.
Résumé Une hypophyse greffée autoplastiquement dans la chambre antérieure de l'il, dans lemanus ou dans letarsus s'est avérée capable de remplacer l'hypophysein situ dans son action sur la régénération et la survie chez le Triton, à condition que s'établisse une vascularisation satisfaisante du greffon et que la durée de l'expérience ne dépasse pas plusieurs mois. 相似文献
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A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution 总被引:31,自引:0,他引:31
The crystal structure of alamethicin in nonaqueous solvent has been determined, and refined at 1.5-A resolution. The molecular conformation of the three crystallographically independent molecules is largely alpha-helical with a bend in the helix axis at an internal proline residue. The helix structure is highly amphipathic as most of the solvent-accessible polar atoms lie on a narrow strip of surface parallel to the helix axis. Molecular models for the voltage-gated ion channel, with n-fold symmetry and based on the molecular conformations observed in the crystal, are characterized by strong surface complementarity, a hydrophilic interior and a hydrophobic exterior. The channel structures are stabilized by a hydrated annulus of hydrogen-bonded glutamine residues which produce the greatest restriction in the channel diameter. 相似文献