成年态南丰蜜橘离体再生芽培养及芽维持的蛋白谱特征

以成年态南丰蜜橘茎段为材料,在不同激素配比的MS培养基中进行再生芽的诱导和继代增殖培养,确定了最佳的诱导培养基改良MS+6-BA0.5 mg/L+KT0.5 mg/L+NAA0.1 mg/L,把诱导培养基中的蔗糖浓度由3%提高到6%可以很好地解决再生芽的叶片发黄、脱落问题;再生芽增殖的最佳培养基为改良MS+6-BA0.4 mg/L+ZT0.1 mg/L+NAA0.05 mg/L,增殖系数达5.40.SDS-PAGE电泳结果表明33.4 kD相对分子质量的蛋白谱带出现于再生芽正常分化生长时期,可能是维持再生芽生长发育的特异蛋白组分.     

融合粗糙集和证据理论的车地无线通信设备故障诊断

针对车地无线通信设备故障诊断信息不一致的情况进行故障推理和诊断,提出了一种融合粗糙集与证据理论综合集成的车地无线通信设备故障诊断方法.该方法首先利用粗糙集剔除故障特征数据的冗余成分,提取互不相关的必需特征,将车地无线通信设备故障诊断问题用一个不同简化层次的故障决策网络表示,由网络节点根据定义出的规则置信度和覆盖度可推导出对应有效的故障诊断规则集合.在建立规则库的基础上,引入基于证据理论的信息融合技术,解决多传感器故障监测数据与诊断规则准确匹配的问题,建立故障推理机制,便可方便得出车地无线通信单元故障诊断结果,实例分析表明该方法能有效提高模型故障诊断能力,具有较强实用性.     

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140?mm?Hg systolic blood pressure or ≥90?mm?Hg diastolic blood pressure). Even small increments in blood pressure are associated with an increased risk of cardiovascular events. This genome-wide association study of systolic and diastolic blood pressure, which used a multi-stage design in 200,000 individuals of European descent, identified sixteen novel loci: six of these loci contain genes previously known or suspected to regulate blood pressure (GUCY1A3-GUCY1B3, NPR3-C5orf23, ADM, FURIN-FES, GOSR2, GNAS-EDN3); the other ten provide new clues to blood pressure physiology. A genetic risk score based on 29 genome-wide significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function. We also observed associations with blood pressure in East Asian, South Asian and African ancestry individuals. Our findings provide new insights into the genetics and biology of blood pressure, and suggest potential novel therapeutic pathways for cardiovascular disease prevention.     

一类特殊圈的交错多项式

介绍了支点操作H uv的概念,并给出了简单图H的交错多项式Q(H,x)的定义和一些已知图的交错多项式,最后计算出图中一类比较特殊的圈的交错多项式.     

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

Cpdm (chronic proliferative dermatitis) mice develop chronic dermatitis and an immunodeficiency with increased serum IgM, symptoms that resemble those of patients with X-linked hyper-IgM syndrome and hypohydrotic ectodermal dysplasia (XHM-ED), which is caused by mutations in NEMO (NF-κB essential modulator; also known as IKBKG). Spontaneous null mutations in the Sharpin (SHANK-associated RH domain interacting protein in postsynaptic density) gene are responsible for the cpdm phenotype in mice. SHARPIN shows significant similarity to HOIL-1L (also known as RBCK1), a component of linear ubiquitin chain assembly complex (LUBAC), which induces NF-κB activation through conjugation of linear polyubiquitin chains to NEMO. Here, we identify SHARPIN as an additional component of LUBAC. SHARPIN-containing complexes can linearly ubiquitinate NEMO and activated NF-κB. Thus, we re-define LUBAC as a complex containing SHARPIN, HOIL-1L, and HOIP (also known as RNF31). Deletion of SHARPIN drastically reduced the amount of LUBAC, which resulted in attenuated TNF-α- and CD40-mediated activation of NF-κB in mouse embryonic fibroblasts (MEFs) or B cells from cpdm mice. Considering the pleomorphic phenotype of cpdm mice, these results confirm the predicted role of LUBAC-mediated linear polyubiquitination in NF-κB activation induced by various stimuli, and strongly suggest the involvement of LUBAC-induced NF-κB activation in various disorders.     

鸡油菌兼性腐生生长的初步研究

鸡油菌是外生菌根真菌,可通过对马尾松侵染形成共生体,本项研究发现鸡油菌还可以兼性腐生.在温度20～24℃、pH值5.5～6.0、松针马铃薯培养基等条件下,栽培当年就能获得大量子实体原基,为探讨鸡油菌培养与人工栽培奠定了基础.     

不确定环境下链与链竞争的纵向控制结构绩效

利用贝叶斯统计推断方法和博弈理论构建市场不确定环境下链与链竞争的控制结构模型,分析市场风险、产品竞争强度对供应链纵向控制结构绩效的影响,从制造商与供应链系统角度识别了不确定环境下纵向控制结构选择的贝叶斯均衡与可能的囚徒困境,特别是,供应链系统控制结构选择不依赖于市场的风险环境,只取决于市场竞争强度,这显著不同于制造商对纵向控制结构选择还依赖于市场风险及零售商预测能力,该结果为不确定环境下链与链竞争的纵向控制结构选择提供了理论基础.     

散货自动化装船策略设计及算法优化

为实现大宗散货自动化装船,设计一种以平衡装载原则、货物堆积平整度和船舶安全性为基础,利用散货物料堆积特性建立理想锥体模型近似模拟物料平整堆积装船效果,建立散货装船物料堆点布置及对应装载量的自动规划策略,提出一种具有自我影响因子的改进型黄金分割法,快速构建理想平整堆积模型,优化自动规划算法效率,最后通过实验验证自动装船策...     

检验库仑反平方定律实验中接触势的影响

分析基于同心导体球壳方法检验库仑反平方定律和光子静止质量的实验中接触势的影响,并分别给出了静态和动态实验中接触势对实验灵敏度的限制.     

房地产金融制度与土地制度联动关系研究

房地产业的发展关系着国计民生,研究如何规范房地产市场具有重要意义.目前还未见到有综合研究土地制度和金融制度对中国房地产市场的影响.本文使用经济学“双缺口”模型解析我国房地产业市场目前的土地、金融两个领域制度创新的联动关系,在此基础上并给出了建设性的指导建议,认为缺乏土地市场制度创新相配合的房地产金融体制改革很大程度上天然是无效的.