基于主题突变检测的颠覆性技术识别——以无人机技术领域为例

 颠覆性技术对实现中国科技创新跨越式发展具有重要战略意义。以无人机技术领域为例，获取Web of Science论文数据库和德温特（Derwent）专利数据库2005—2019年收录的2812篇论文与专利数据，基于LDA-LSTM文本分类算法得到技术主题，采用CiteSpace构建共现网络，从突变权重排序及突变时间段和突变共词聚类知识图谱2个角度进行主题突变检测，进而识别出无人机交互技术中的脑机接口技术及手势控制技术为该领域内的颠覆性技术，通过2020年无人机技术领域相关论文专利验证了识别框架的有效性。     

The effects of topical succinylcholine on single unit and electrocorticographic activity

Summary Topical succinylcholine induces massive epileptiform discharges in the electrocorticogram, coinciding with the bursting or tonic activity of single cortical cells.     

一类含零导数的算子方程分歧解的存在性

该文用同伦法和拓朴度证明一类含零导数的算子方程μＡｘ＋Ｎ（μ，ｘ）＝０，在（μ，ｘ）＝（０，０）附近分歧解的存在性，其中ｘ∈Ｘ，μ∈（０，μ０）。Ｘ和Ｙ是Ｂａｎａｃｈ空间。Ａ：Ｘ→Ｙ是零指标Ｆｒｅｄｈｏｌｍ有界线性算子。对固定的μ∈（０，μ０），Ｎ：Ｘ→Ｙ是非线性全连续算子，且满足Ｎ（μ，０）＝０，对一切μ∈Ｒ。当ｘ→０时，Ｎ（μ，ｘ）＝ｏ（ｘ）。当ｘ→＋∞时，Ｎ（μ，ｘ）／ｘ→＋∞。对充分小ｒ＞０，当ｘ≥ｒ时，Ｎ（μ，ｘ）≥μαｘ１＋δ，其中α＜１，δ＞０，μ∈（０，μ０）。ｋｅｒＡ是ｎ维空间。在上述条件下，证明了在（０，０）点附近存在非平凡解ｘ（μ），且μ→０＋时，ｘ（μ）→０。     

A sodium-channel mutation causes isolated cardiac conduction disease

Cardiac conduction disorders slow the heart rhythm and cause disability in millions of people worldwide. Inherited mutations in SCN5A, the gene encoding the human cardiac sodium (Na+) channel, have been associated with rapid heart rhythms that occur suddenly and are life-threatening; however, a chief function of the Na+ channel is to initiate cardiac impulse conduction. Here we provide the first functional characterization of an SCN5A mutation that causes a sustained, isolated conduction defect with pathological slowing of the cardiac rhythm. By analysing the SCN5A coding region, we have identified a single mutation in five affected family members; this mutation results in the substitution of cysteine 514 for glycine (G514C) in the channel protein. Biophysical characterization of the mutant channel shows that there are abnormalities in voltage-dependent 'gating' behaviour that can be partially corrected by dexamethasone, consistent with the salutary effects of glucocorticoids on the clinical phenotype. Computational analysis predicts that the gating defects of G514C selectively slow myocardial conduction, but do not provoke the rapid cardiac arrhythmias associated previously with SCN5A mutations.     

论审美距离

布洛提出审美“距离说”时,肯定认识到了审美中主客体之间物理距离与心理距离的相似性、可比性,应当从物理与心理相统一的角度来认识审美距离。物理距离指主客体之间的物质远近,主体能保证将认识清楚的空间、时间是合适的物理距离,主体对客体的利害已经有所认识,但在欣赏的当下却不加注意和考虑是合适的心理距离。     

双精度数字散斑振动测量系统

给出了一种双精度数字散班振动测量系统。该系统结合了普通数字散斑离面振动测量光路和退敏感光路,可以对物体的振动进行高精度和低精度２次测量,并利用低精度的测量结果对高精度的测量结果进行相位去包裹。由于这种去包裹方法是各点独立进行的,使得该系统可以测量工程实际中复杂的非连续体的振动。     

ZrNi金属玻璃中ZrxNin-x(n≤6)团簇形成的量子化学研究

根据化学键理论与拓扑原理,设计了ＮｉｘＺｒ６－ｘ团簇的可能几何结构,并用从头算方法进行了构型优化,结果表明,小团簇Ｎｉ,Ｚｒｎ－ｘ（ｎ≤５）倾向于生成平面结构,而６原子团簇则是八面体或三棱柱构型更,在大部分情况下Ｚｒ原子把电荷转移ｉ原子。     

含柔性间隔聚水杨醛亚胺及其Cu2+络合物的合成与液晶性

采用分子设计手段合成了含一定柔性间隔的聚水杨醛亚胺,并与Cu