泥石流危险性动量分区方法与应用

运用泥石流运动数值模拟和GIS相结合的方法模拟泥石流出山口后的运动全过程, 求得泥石流流速和流深分布, 确定泥石流过程中泛滥范围内任一点的最大动量, 建立了泥石流危险性动量分区模型Z = Khv. 根据考察和实验资料对委内瑞拉首都加拉加斯的Chacaito沟百年一遇泥石流运动过程进行了模拟, 利用动量分区方法划分出泥石流危险区.     

连续系统振动特征值摄动问题的统一解法

将离散系统振动分析中的通用的矩阵摄动法推广到连续系统。采用弹性结构理论算子，对连续系统的振动特征值摄动问题进行统一描述。根据特征函数子空间缩聚法和正交分解的基本原理，推导了统一的摄动公式。该方法能同时有效地处理孤立、重及密集特征值3种不同情况。以薄膜振动和变厚度薄板弯曲振动的特征值问题为例，阐明了方法的实际应用。     

Differential effects of the serotonin receptors on cultured rat cerebral cortical neurons

Effects of serotonin (5-HT) on cerebral cortical neurons were examined by patch clamp techniques. 5-HT produced a variety of responses such as outward (19/73 patches/neurons), slow inward (15/73 patches/neurons), fast inward (8/73 patches/neurons), and mixed currents (initially fast inward deflection followed by an outward response: 2/73 patches/neurons), with a latency of 12 sec, 15 sec, 0 sec, and 0 sec respectively, at a holding potential of −60 mV in whole-cell patches. The fast inward currents were again evoked by a selective 5-HT3 receptor agonist, 1-(m-chlorophenyl)-biguanide hydrochloride (CPBG). In the cell-attached patch clamp configuration, 5-HT inside the patch pipette elicited single channel currents with slope conductances of 42 pS and 132 pS (4/42 patches/neurons). CPBG inside the patch pipette evoked inward single channel currents with a lower slope conductance of 41 pS (3/23 patches/neurons). In contrast, application of 5-HT or a 5-HT₂ receptor agonist, α-methyl-5-hydroxytryptamine-maleate, outside the patch pipette induced outward single channel currents with a major slope conductance of 140 pS (8/30 patches/neurons) or 135 pS (6/20 patches/neurons), respectively. These results indicate that the outward and fast inward currents may be mediated respectively by the 5-HT₂ receptor, which is coupled to a G-protein, and by the 5-HT₃ receptor, which contains the non-selective cation channel, and that the mixed type may be caused by both the 5-HT₂ and 5-HT₃ receptors. Received 27 September 1996; received after revision 4 November 1996; accepted 7 November 1996     

Effect of hydrogen peroxide on the binding of Merocyanine 540 to human erythrocytes

The fluorescent dye Merocyanine 540 (MC540) is often used as a probe to monitor the molecular packing of phospholipids in the outer leaflet of biomembranes. In a previous study we showed that the increased staining of erythrocytes with a perturbed membrane structure was mainly due to an increase in the fluorescence yield of cell-bound MC540, rather than to an increase of the number of bound molecules. Erythrocytes and ghosts exposed to continuous fluxes of H₂O₂ exhibited pronounced lipid peroxidation. Further, red blood cells subjected to this form of oxidative stress also showed increased staining with MC540. It appeared that this was caused by a strong increase in binding of MC540, together with a slight red shift of the fluorescence emission maximum and a small increase in the fluorescence yield of bound MC540. The changed MC540 binding characteristics were not observed when lipid peroxidation was suppressed by the presence of the antioxidant BHT in the incubation medium. However, open ghosts exposed to H₂O₂ showed no increase of MC540 binding, excluding a direct involvement of lipid peroxidation. Measurement of fluorescence emission spectra and gel filtration studies showed that MC540 can bind to H₂O₂-exposed hemoglobin. Experiments with erythrocytes lysed in hypotonic medium after exposure to H₂O₂ revealed that peroxidation of lipids with H₂O₂ induced a non-specific permeabilization of the plasma membrane to MC540, thereby allowing MC540 to bind to the oxidatively denatured, more hydrophobic hemoglobin. These results indicate that conclusions about packing of phospholipids in the outer leaflet of the membrane based on increased MC540-staining should be drawn with care. Received 27 September 1996; received after revision 5 November 1996; accepted 27 November 1996     

Spectrum characteristics and pump wavelengths of Nd3+-doped double-clad fiber

Conclusion The optimum wavelength of Nd³⁺-doped double-clad fiber laser or amplifier made in China is near 830 nm. The efficiency of Nd³⁺-doped double-clad fiber devices pumped by 820-nm laser is low due to ESA. In order to increase the photochemical stability of the outer cladding, the material of the outer cladding must be advanced.     

两种线分维及线分维与面分维间关系

分别用二次电子扫描线法和垂直抛面法对不同回火制度的３０ＳｉＭｎＣｒＮｉＭｏＢ钢的冲击断口表面的分维数进行了数量。通过研究发现：平行裂纹扩展方向的分维更适合于描述材料韧性的变化。     

卟吩质子化过程结构变化的理论研究

用ＡＭ１ＭＯ方法计算了质子化卟吩的构型，并通过结构分析、电荷布局分析和前线轨道分析，讨论了其质子化过程的构型变化及Ｒａｍａｎ光谱变化的原因。     

复杂载荷下的疲劳寿命估算

从疲劳过程本质上是材料静强度不断退化过程的观点出发，建立了一个强度退化模型．将模型应用于两级、多级和随机载荷下疲劳寿命估算，经试验和算例验证，表明该方法是合理可行的