拟面向对象和面向对象智能决策支持系统开发环境

根据实际开发的经验，探讨拟面向对象和面向对象型智能决策支持系统开发环境的设计思想、基本结构、六大功能模块对象类库及用该环境开发拟面向对象型和面向对象型决策支持系统的有关步骤。     

无限维离散不可控系统二次判据问题讨论

通过构造一个范数，并利用动态规划原理对无限维离散不可控系统二次判据问题进行了讨论，得到了最优反馈控制的存在唯一性，以及自治情形下的Ｒｉｃｃａｔｉ方程。     

一种标定立体成像系统的新方法

在立体成像系统中，两相机的位置、取向、倾角由于机械上的困难，很难保证固定不变。因此，在匹配问题解决后，必须对成像系统进行标定，才能最终提取关于景物的三维信息，基于此，提出了一种成像系统的模型及其误差量定义，同时给出了用最小二乘法拟合立体成像系统参数的算法。     

一种立体视觉图像的特征选择与匹配方法

从立体图像对中获取精确的三维信息需要进行相机建模、标定和图像点的匹配［１，２］．提出了特征点的选取；利用金字塔图像结构进行立体匹配，以及对匹配点进行整体性检验的准则。实验表明，该算法匹配速度快，错误概率小，匹配点在整个景物中分布均匀。     

基于小波包的信号检测算法

针对多个相似信号分量的到达时间检测问题提出了一种基于小波包理论的新算法（ＷａｖｅｌｅｔＰａｃｋｅｔｓＤｅｔｅｃｔｉｏｎＡｌｇｏｒｉｔｈｍ，ＷＰＤＡ）．即使在各信号分量严重重叠的情况下，该算法都能非常精确地确定各分量的到达时间。为了进行比较，引用了Ｂ．Ｆｒｉｅｄｌａｎｄｅｒ提出的改进Ｇａｂｏｒ表征方法（ＩＧＲＭ）及其信号模型。实验证明，小波包检测算法可以得到更为优越的性能。还讨论了小波包检测算法中的正交镜像滤波器选择问题。     

基于LPC预测误差DWT的语音基音检测

在对语音信号进行ＬＰＣ分析的基础上，提出了一种有效的语音基音周期检测算法。该算法利用小波变换中著名的Ｍａｌｌａｔ算法逐层分解ＬＰＣ预测误差信号，在最低分辨率的逼近信号中寻找峰值，然后逐层回溯各个分辨率的逼近信号，最后在ＬＰＣ预测误差中确定出峰值，从而求出相应的基音周期。     

Baclofen prevents rapid amygdala kindling in adult rats

This study investigates the effect of the gamma-aminobutyric acid (GABA_B) agonist, baclofen, on amygdala kindling in adult rats. Baclofen has been reported to be anticonvulsant in a variety of seizure models and prevents kindling in immature rats. These experiments describe the effects of baclofen (2, 5 and 10 mg/kg, i.p.) on the afterdischarge threshold and kindling rate. Baclofen, 10 mg/kg, significantly increased the afterdischarge threshold in the amygdala. Baclofen at 5 and 10 mg/kg, retarded the rate of kindling as measured by the number of stimuli required to advance to subsequent seizure stages. These results suggest that baclofen may decrease the local excitability of the amygdala and retard the rate of seizure spread (or generalization) throughout the brain. Baclofen, acting at GABA_B receptors exerts an anticonvulsant effect on amygdala kindling in these experiments.     

Gene inactivation triggered by recognition between DNA repeats

This chapter focuses on phenomena of gene inactivation resulting from the presence of repeated gene copies within the genome of plants and fungi, and on their possible relationships to homologous DNA-DNA interactions. Emphasis is given to two related premeiotic processes: Methylation Induced Premeiotically (MIP) and Repeat-Induced Point mutation (RIP) which take place in the fungiAscobolus immersus andNeurospora crassa, respectively. The relationships between these processes and genetic recombination are discussed.     

Dissociated cell suspensions ofCarcinus maenas Y-organs as a tool to study ecdysteroid production and its regulation

In vitro ecdysteroid production by dissociated Y-organ cells of the shore crabCarcinus maenas was characterized during short-term incubations. Under optimized conditions (M199 adjusted to crab osmolality and with the addition of 10% foetal calf serum), ecdysteroid production by dispersed cells increased linearly during 4-hour incubations, with little intra-assay variation. 25-deoxyecdysone was mainly produced. PurifiedCarcinus molt inhbiting hormone (CamMIH) produced a dose-dependent inhibition of ecdysteroid production by dispersed cells. The cells were about 50 times more sensitive than whole glands to MIH. Other structurally-related peptides were tested.     

Protective effect of Shigyaku-to,a traditional Chinese herbal medicine,on the infection of herpes simplex virus type 1 (HSV-1) in mice

The antiviral activity of Shigyaku-to (TJS-109), a traditional Chinese herbal medicine, was investigated in mice infected with herpes simplex virus type 1 (HSV-1). TJS-109 is a combination of the medicinal plant extracts fromZingiberis siccatum rhizoma,Aconiti tuber andGlycyrrhizae radix in a specific proportion. Mice infected with a 10 LD₅₀ dose of HSV-1 were treated with TJS-109 orally at doses of 1.25 to 20 mg/kg 2 days before, and 1 and 4 days after the infection. The treated groups had 80% (1.25 mg/kg), 40% (5 mg/kg) and 23% (20 mg/kg) mortality rates 25 days after the infection as compared with a 100% mortality rate in control mice treated with saline. When HSV-1 infected mice (recipients) received CD8⁺T cell fractions derived from spleens of mice treated with TJS-109 (donors), 70% of recipients survived, as compared with 0% survivors in the groups of mice treated with saline, B cell fractions, CD4⁺ T cell fractions or macrophage-enriched fractions prepared from the same donors. TJS-109 did not show any virucidal activities against HSV-1 or any virostatic activities on the growth of HSV-1 in Vero cells. These results suggest that TJS-109 protected mice exposed to lethal amounts of HSV-1 through the activation of CD8⁺ T cells.