全文获取类型
收费全文 | 4606篇 |
免费 | 27篇 |
国内免费 | 43篇 |
专业分类
系统科学 | 48篇 |
丛书文集 | 45篇 |
教育与普及 | 165篇 |
理论与方法论 | 15篇 |
现状及发展 | 286篇 |
研究方法 | 627篇 |
综合类 | 3481篇 |
自然研究 | 9篇 |
出版年
2019年 | 3篇 |
2017年 | 6篇 |
2016年 | 7篇 |
2015年 | 4篇 |
2014年 | 14篇 |
2013年 | 20篇 |
2012年 | 297篇 |
2011年 | 350篇 |
2010年 | 116篇 |
2009年 | 98篇 |
2008年 | 407篇 |
2007年 | 372篇 |
2006年 | 438篇 |
2005年 | 507篇 |
2004年 | 320篇 |
2003年 | 312篇 |
2002年 | 268篇 |
2001年 | 198篇 |
2000年 | 303篇 |
1999年 | 98篇 |
1998年 | 44篇 |
1997年 | 22篇 |
1996年 | 16篇 |
1995年 | 8篇 |
1994年 | 11篇 |
1993年 | 22篇 |
1992年 | 11篇 |
1991年 | 16篇 |
1990年 | 14篇 |
1989年 | 25篇 |
1988年 | 11篇 |
1987年 | 7篇 |
1986年 | 17篇 |
1985年 | 14篇 |
1984年 | 20篇 |
1983年 | 13篇 |
1982年 | 21篇 |
1981年 | 8篇 |
1980年 | 6篇 |
1979年 | 8篇 |
1971年 | 9篇 |
1970年 | 8篇 |
1966年 | 6篇 |
1959年 | 24篇 |
1958年 | 57篇 |
1957年 | 27篇 |
1956年 | 24篇 |
1955年 | 17篇 |
1954年 | 25篇 |
1948年 | 12篇 |
排序方式: 共有4676条查询结果,搜索用时 0 毫秒
991.
Charles H. Cox 《国外科技新书评介》2005,(6):13-14
本书介绍模拟光链路的设计基础。首先介绍用在直接和外调制两者中公用的电一光元件小信号模型的发展,并用分析工具,逐一详细分析光链路的四个重要参数:增益、带宽、噪声系数和动态范围,最后探索四个重要链路参数间的一些折衷办法。 相似文献
992.
Michael Nash 《国外科技新书评介》2005,(6):8-8
这是一本Java编程人员的实用工具书。它用平实的语言介绍了框架与组件技术的诸多优点,特别是它们与Web应用开发的关系。本书并不集中于某一特定技术,而是用从不同框架中提取出的例子来说明一些内在的基本原则。这可以帮助开发者了解哪种框架更适合于他们的开发目标。 相似文献
993.
介绍多次微量技术制取锆钛酸铅薄膜。XRD分析表明:经高温退火处理后的薄膜呈与源材料一致的钙钛矿结构,增加退火时间能减少残存Pb3O4的数量;电滞回线检测表明,薄膜具有铁电特性。 相似文献
994.
Identification of CRE1 as a cytokinin receptor from Arabidopsis 总被引:29,自引:0,他引:29
Inoue T Higuchi M Hashimoto Y Seki M Kobayashi M Kato T Tabata S Shinozaki K Kakimoto T 《Nature》2001,409(6823):1060-1063
Cytokinins are a class of plant hormones that are central to the regulation of cell division and differentiation in plants. It has been proposed that they are detected by a two-component system, because overexpression of the histidine kinase gene CKI1 induces typical cytokinin responses and genes for a set of response regulators of two-component systems can be induced by cytokinins. Two-component systems use a histidine kinase as an environmental sensor and rely on a phosphorelay for signal transduction. They are common in microorganisms, and are also emerging as important signal detection routes in plants. Here we report the identification of a cytokinin receptor. We identified Arabidopsis cre1 (cytokinin response 1) mutants, which exhibited reduced responses to cytokinins. The mutated gene CRE1 encodes a histidine kinase. CRE1 expression conferred a cytokinin-dependent growth phenotype on a yeast mutant that lacked the endogenous histidine kinase SLN1 (ref. 10), providing direct evidence that CRE1 is a cytokinin receptor. We also provide evidence that cytokinins can activate CRE1 to initiate phosphorelay signalling. 相似文献
995.
内点法作为一种高效的非线性规划算法,其简约空间算法实现尤其适于求解过程系统工程中的高维、低自由度优化问题,从而算法只需要在决策变量的低维空间寻求最优解,并且求解性能不依赖于模型的精确二阶导数信息,这对难以获得二阶导数或者二阶导数计算代价很大的复杂系统优化极为重要。为了保障简约空间内点法的全局收敛性,本文提出了与内点法共享空间分解结构的投影梯度可行性恢复算法。该算法结合了信赖域与线性搜索方法的优点,能够有效促进内点法的全局收敛。通过求解经典文献及CUTE/COPS算例库中的优化问题验证了本文提出算法的有效性。 相似文献
996.
本书是《剑桥粒子物理、核物理和宇宙学》专著的第十七卷,是为该领域博士生提供的关于微扰与非微扰QCD理论的一本教学参考书,全面和细致的阐述了该领域的现代发展状况,特别是QCD谱求和规则(QSSR)的最新成果以及它们与其它非微扰QCD方法的比较。 相似文献
997.
998.
Cenozoic motion between East and West Antarctica 总被引:2,自引:0,他引:2
The West Antarctic rift system is the result of late Mesozoic and Cenozoic extension between East and West Antarctica, and represents one of the largest active continental rift systems on Earth. But the timing and magnitude of the plate motions leading to the development of this rift system remain poorly known, because of a lack of magnetic anomaly and fracture zone constraints on seafloor spreading. Here we report on magnetic data, gravity data and swath bathymetry collected in several areas of the south Tasman Sea and northern Ross Sea. These results enable us to calculate mid-Cenozoic rotation parameters for East and West Antarctica. These rotations show that there was roughly 180 km of separation in the western Ross Sea embayment in Eocene and Oligocene time. This episode of extension provides a tectonic setting for several significant Cenozoic tectonic events in the Ross Sea embayment including the uplift of the Transantarctic Mountains and the deposition of large thicknesses of Oligocene sediments. Inclusion of this East-West Antarctic motion in the plate circuit linking the Australia, Antarctic and Pacific plates removes a puzzling gap between the Lord Howe rise and Campbell plateau found in previous early Tertiary reconstructions of the New Zealand region. Determination of this East-West Antarctic motion also resolves a long standing controversy regarding the contribution of deformation in this region to the global plate circuit linking the Pacific to the rest of the world. 相似文献
999.
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults 总被引:5,自引:0,他引:5
Zacchi P Gostissa M Uchida T Salvagno C Avolio F Volinia S Ronai Z Blandino G Schneider C Del Sal G 《Nature》2002,419(6909):853-857
1000.
Jørgensen R Merrill AR Yates SP Marquez VE Schwan AL Boesen T Andersen GR 《Nature》2005,436(7053):979-984
The bacteria causing diphtheria, whooping cough, cholera and other diseases secrete mono-ADP-ribosylating toxins that modify intracellular proteins. Here, we describe four structures of a catalytically active complex between a fragment of Pseudomonas aeruginosa exotoxin A (ETA) and its protein substrate, translation elongation factor 2 (eEF2). The target residue in eEF2, diphthamide (a modified histidine), spans across a cleft and faces the two phosphates and a ribose of the non-hydrolysable NAD+ analogue, betaTAD. This suggests that the diphthamide is involved in triggering NAD+ cleavage and interacting with the proposed oxacarbenium intermediate during the nucleophilic substitution reaction, explaining the requirement of diphthamide for ADP ribosylation. Diphtheria toxin may recognize eEF2 in a manner similar to ETA. Notably, the toxin-bound betaTAD phosphates mimic the phosphate backbone of two nucleotides in a conformational switch of 18S rRNA, thereby achieving universal recognition of eEF2 by ETA. 相似文献