战区反导拦截效率模型研究

在未来防空作战中,反战术弹道导弹(TBM)是防空导弹部队担负的重要作战任务。针对拦截战术弹道导弹过程中,难以用一般预警雷达完成情报预警的问题,建立了情报预警系统的发现概率和预警概率计算模型,以及防空导弹拦截系统的排队论模型,给出了反导作战拦截效率的计算方法,并讨论了提高反导拦截效率的对策与方法     

科学与理性

编者按:本栏摘登了由青年学者刘华杰博士主持的关于"敬畏自然"话题讨论的部分内容.这个话题,自从印度洋海啸发生之后引起了我国学术界人士的普遍关注,并在某些报刊上展开了热烈的讨论.这里刊发的是四位青年学者从文化层面对"敬畏自然相关问题"发表的意见,供读者参阅.     

简单正交多阵SOMA(4,n)的存在性

设整数k0,n≥2,简单正交多阵SOMA(k,n)是一个n×n的方阵A,它的每一个单元格包含kn-元集S的一个k-元子集且满足:1)S的每个元素在A的每一行和每一列恰好出现一次;2)S的每个2-元子集至多出现在A的一个单元格中.总结了SOMA(k,n)存在的最新结果,并且阐述了它和相互正交拉丁方之间的关系,同时通过直接构造的方法证明了n≥5,SOMA(4,n)的存在性,并且提出了进一步研究的问题.     

Microstructural characterization and oxidation resistance of multicomponent equiatomic CoCrCuFeNi-TiO high-entropy alloy

CoCrCuFeNi-TiO was prepared by arc melting of the pure elements and Ti₂CO powder under an Ar atmosphere. Both CoCrCuFeNi and CoCrCuFeNi-TiO alloys are composed of a face-centered cubic (fcc) solid solution, whereas the alloys of CoCrCuFeNi-TiO are basically composed of an fcc solid solution and TiO crystals. The microstructures of CoCrCuFeNi-TiO are identified as dendrite and interdendrite structures such as CoCrCuFeNi. The morphology of TiO is identified as an equiaxed crystal with a small amount of added Ti₂CO. By increasing the amount of Ti₂CO added, the TiO content was dramatically increased and part of the equiaxed crystals changed to a dendrite structure. A test of the oxidation resistance demonstrates that the oxidation resistance of CoCrCuFeNi-TiO is better than that of CoCrCuFeNi. However, as the TiO content increases further, a corresponding decrease is observed in the oxidation resistance.     

薄铺层复合材料薄壁管轴压屈曲行为研究

在薄壁结构的应用中,屈曲稳定性是影响其承载性能的关键因素,为研究减薄铺层厚度对复合材料薄壁结构局部屈曲行为的影响,本文采用不同厚度(0.125、0.055和0.020 mm)的预浸料制备复合材料薄壁管,实验测试了其在轴压下的局部屈曲行为.实验结果表明,随着铺层厚度减薄,实验采用的正交和均衡两种铺层方式的复合材料薄壁管局部屈曲载荷均随之提高,而屈曲失效模式没有发生改变.力学分析表明,铺层厚度减薄后,管壁弯曲刚度的改变和层间剪切应力分布对薄壁管局部屈曲载荷提高有重要影响.采用薄铺层制备复合材料薄壁结构件能够有效提高其局部屈曲能力.     

An efficient identity-based key agreement protocol in a multiple PKG environment

Identity-based key agreement protocol affords a natural way to combine the participant’s identity with its public key.However,most of them just consider the key agreement in a single private key generator(PKG)environment.In addition,the existing key agreement protocols have a great computing overhead for mobile computing which is more and more popular today.This paper proposes a new identity based key agreement protocol.With the help of mathematical tools,we make our protocol applied in multiple PKG environment.It also satisfies all the security properties which is set for key agreement protocol.Moreover,some of its time-consuming operations can be delivered to untrusted public computation resources,so its computing complexity can be greatly reduced.     

河北省高校区域创新体系服务调查研究

高校是区域创新体系的重要主体要素。近年来,高校凭借其雄厚的科研基础和集聚的科研人才,迅速成为推动区域经济和社会发展的主要生长点和辐射源。研究通过对河北省高校为区域创新体系发展提供人才培养培训服务、平台服务和资源保障的实际情况,总结高校服务取得的成绩和存在的问题,并提出相关发展对策和建议。     

苯并[1，2-b：4，5-b’]二噻吩-thieno[3，4-易]thiadiazole导电性的理论研究

采用密度泛函理论，在B3LYP／6—31G（d）水平下，对苯并[1，2-b：4，5-b’]二噻吩（BDT）-thieno[3，4-b]thiadiaz01e（TD）的低聚物和聚合物进行了理论计算．其中，BDT为电子供体，TD为电子受体，以1：2的方式结合形成化合物，并计算了二面角、分子内的电荷传输、桥键键长和中心键电荷密度．结果显示：随着聚合链增长，共轭程度增加．NICSs值显示：中心环比边环的共轭程度更大．聚合物的能带结构表明：该聚合物的带隙比较低（0．87eV），故其可以作为潜在的导电材料．     

Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD

The type III receptor tyrosine kinase FLT3 is frequently mutated in acute myeloid leukemia. Oncogenic FLT3 mutants display constitutive activity leading to aberrant cell proliferation and survival. Phosphorylation on several critical tyrosine residues is known to be essential for FLT3 signaling. Among these tyrosine residues, Y842 is located in the so-called activation loop. The position of this tyrosine residue is well conserved in all receptor tyrosine kinases. It has been reported that phosphorylation of the activation loop tyrosine is critical for catalytic activity for some but not all receptor tyrosine kinases. The role of Y842 residue in FLT3 signaling has not yet been studied. In this report, we show that Y842 is not important for FLT3 activation or ubiquitination but plays a critical role in regulating signaling downstream of the receptor as well as controlling receptor stability. We found that mutation of Y842 in the FLT3-ITD oncogenic mutant background reduced cell viability and increased apoptosis. Furthermore, the introduction of the Y842 mutation in the FLT3-ITD background led to a dramatic reduction in in vitro colony forming capacity. Additionally, mice injected with cells expressing FLT3-ITD/Y842F displayed a significant delay in tumor formation, compared to FLT3-ITD expressing cells. Microarray analysis comparing gene expression regulated by FLT3-ITD versus FLT3-ITD/Y842F demonstrated that mutation of Y842 causes suppression of anti-apoptotic genes. Furthermore, we showed that cells expressing FLT3-ITD/Y842F display impaired activity of the RAS/ERK pathway due to reduced interaction between FLT3 and SHP2 leading to reduced SHP2 activation. Thus, we suggest that Y842 is critical for FLT3-mediated RAS/ERK signaling and cellular transformation.     

Two Innovative Coalition Formation Models for Dynamic Task Allocation in Disaster Rescues

This paper addresses the problem of multi-objective coalition formation for task allocation. In disaster rescue, due to the dynamics of environments, heterogeneity and complexity of tasks as well as limited available agents, it is hard for the single-objective and single (task)-to-single (agent) task allocation approaches to handle task allocation in such circumstances. To this end, two multi-objective coalition formation for task allocation models are proposed for disaster rescues in this paper. First, through coalition formation, the proposed models enable agents to cooperatively perform complex tasks that cannot be completed by single agent. In addition, through adjusting the weights of multiple task allocation objectives, the proposed models can employ the linear programming to generate more adaptive task allocation plans, which can satisfy different task allocation requirements in disaster rescue. Finally, through employing the multi-stage task allocation mechanism of the dynamic programming, the proposed models can handle the dynamics of tasks and agents in disaster environments. Experimental results indicate that the proposed models have good performance on coalition formation for task allocation in disaster environments, which can generate suitable task allocation plans according to various objectives of task allocation.