Inhibition of transplanted mouse tumors by heterologous transfer RNA

Summary Injections of yeast tRNA to C57BL mice decreased takes and inhibited growth of syngeneic transplanted tumors. Mice remaining free of tumors as result of this treatment failed to develop tumors after challenge with 5×10⁴ cells of the same tumor.This work was supported in part by a grant from the Stanley Johnson Foundation, Berne, Switzerland.     

Climate change and the resurgence of malaria in the East African highlands

The public health and economic consequences of Plasmodium falciparum malaria are once again regarded as priorities for global development. There has been much speculation on whether anthropogenic climate change is exacerbating the malaria problem, especially in areas of high altitude where P. falciparum transmission is limited by low temperature. The International Panel on Climate Change has concluded that there is likely to be a net extension in the distribution of malaria and an increase in incidence within this range. We investigated long-term meteorological trends in four high-altitude sites in East Africa, where increases in malaria have been reported in the past two decades. Here we show that temperature, rainfall, vapour pressure and the number of months suitable for P. falciparum transmission have not changed significantly during the past century or during the period of reported malaria resurgence. A high degree of temporal and spatial variation in the climate of East Africa suggests further that claimed associations between local malaria resurgences and regional changes in climate are overly simplistic.     

具有高代数免疫阶布尔函数的构造

在探讨密码学中布尔函数性质的基础上，提出了一个具有高代数免疫阶布尔函数的构造方法，利用这种方法可以构造出一类具有高代数免疫阶的布尔函数，并给出了一个实例。     

Emission-Based Scatter Correction in SPECT Imaging

Scatter correction in single photon emission computed tomography(SPECT) has been focused on either using multiple-window acquisition technique or the scatter modeling technique in iterative image reconstruction.We propose a technique that uses only the emission data for scatter correction in SPECT.We assume that the scatter data can be approximated by convolving the primary data with a scatter kernel followed by the normalization using the scatter-to-primary ratio(SPR).Since the emission data is the superpo...     

Rendering Grass Blowing in the Wind with Global Illumination

We have simulated a time varying wind field using the lattice Boltzmann model, and its effect on blades of grass with a simple mass-spring model. We present a global illumination model for multiple scattering of incident sun and sky illumination within the field of grass. We model the grass as a continuous distribution of infinitesimal colored scattering flakes and solve a system of differential equations for the radiance transport. We repeat this for a collection of grass bending directions and amounts, an...     

广西崇左江州木榄山智人洞古人类遗址及其地质时代

关于现代智人起源的争论一直是国际古人类学研究的前沿与热点. 最近, 在广西崇左木榄山智人洞发现了具有现代人解剖特征初始状态的人类下颌骨化石及大量与之共生的哺乳动物化石. 木榄山智人洞哺乳动物群以江南象与初现的亚洲象及巨獏等组合为其特征, 截然不同于华南早更新世的巨猿动物群和中更新世的大熊猫-剑齿象动物群, 是典型亚洲象动物群的早期代表. 依动物群性质、地层对比及铀系年代测定木榄山化石智人和伴生的哺乳动物群的时代为距今约11万年的晚更新世早期. 该动物群主要由热带-亚热带型动物组成, 但木榄山动物群中森林型动物种类单调, 草地类型的动物相当多, 这表明当时的气候可能比以前干燥. 木榄山智人的发现对研究现代人起源及其环境背景具有非常重要的意义.     

板块构造启动的时间和机制:理论和经验探索

板块构造是指位于对流地幔圈层之上的岩石圈的水平运动,主要由岩石圈在俯冲带的下沉作用所致.板块构造是一个典型的、非平衡复杂体系的自组系统(selforganizing,far from equilibrium complex system,SOFFECS),其驱动力主要来自热边界层(岩石圈)的反向浮力,同时又受控于变形岩石圈与下覆粘性软流圈地幔的耗散作用.在太阳系内侧5个硅酸质行星中,板块构造仅发育于地球,这表明板块构造是硅酸质行星不太常见的一种热散逸方式.目前还不清楚这种构造活动和热散逸方式在地球上是从何时开始的.所有的硅酸质行星在形成初期可能都经历过一次短暂的岩浆海阶段.行星固结后,静止盖层模式是行星冷却的共同途径,即行星表面形成了一个不易活动的固化盖层,此时内部的热量只能通过拆沉作用、热点火山作用和岩浆浅部侵位等方式进行逃逸.由于地球早期温度较高,通过减压熔融形成的岩石圈结构不同于现代岩石圈,即地球早期岩石圈由厚的洋壳和薄的岩石圈地幔构成.这种岩石圈要产生反向浮力需要非常长的时间,因此地球早期即便有板块构造存在,其规模也比较零星.只有当地球冷却到一定程度,扩张中脊下部减压熔融形成薄的洋壳且大洋岩石圈只需几十个百万年就可以产生反向浮力时,才能形成与现今风格相似的、可持续性的板块构造.板块构造启动时间的认识最终取决于人们对相关地质记录(事件)的研究成果.板块构造的判别依据包括蛇绿岩、蓝片岩、超高压变质带、榴辉岩、被动大陆边缘、转换断层、指示克拉通陆块移动轨迹的古地磁研究以及岩浆岩地球化学和同位素构造判别等等.对地质记录的解释必须综合各方面的信息.本人认为现存的地质事件记录了地球构造随时间演化的过程,即太古代时期构造和岩浆活动剧烈,大约在1.9 Ga时开始出现近似的板块构造,在新元古代才开始出现与现代相似的、可持续的、具有深俯冲和板片拖曳特性的板块构造.     

青藏高原现代食草动物牙齿珐琅质稳定同位素特征及古高度重建意义

食草动物牙齿珐琅质具有非常强的抗成岩改造特征, 被认为是研究生态环境变化和重建古高度的理想载体之一. 对青藏高原腹地现代食草动物(牦牛、藏野驴、藏羚羊)牙齿珐琅质的稳定同位素进行了分析, 拉萨地块和羌塘南部地区食草动物牙齿珐琅质δ¹³C(PDB)平均值为－11.3‰ ± 1.1‰, 羌塘北部和可可西里地区为－10.2‰ ± 1.4‰, 与高原以C3植物为主的植被景观是一致的; δ¹⁸O(PDB)值也同样表现出从南向北逐渐升高的趋势, 喜马拉雅山地区吉隆盆地平均值最低, 为－11.8‰ ± 3.4‰, 拉萨地块和羌塘南部地区平均值为－11.1‰ ± 1.1‰, 羌塘北部和可可西里地区最高, 为－9.0‰ ± 1.1‰. 食草动物牙齿珐琅质氧同位素是河水(或降水)与食物(植物)氧同位素的混合, 不适合直接用来进行高度预测. 建立了高原现代食草动物牙齿珐琅质氧同位素对降水、植被及高度的响应关系, 为利用食草动物牙齿化石氧同位素重建青藏高原古高度提供了依据.