冷带轧机液压厚控系统动态数学模型分析与测试

分析了液压厚度控制系统动态数学模型．并与频率特性测试仪所测结果做了比较．得出了实用的被控对象结构图．为厚度控制系统的设计提供了理论依据．     

求解带不可微项方程的平方根法

给出了求解带不可微项方程的平方根迭代法,并利用优序列技巧,在γ-条件下,证明了该迭代法的收敛性,并给出了误差估计。     

关于Liénard方程极限环的不存在性

本文讨论Ｌｉéｎａｒｄ方程的极限环问题,得到若干个Ｌｉéｎａｒｄ方程无环的充分条件。     

糠醛吸附干燥过程中的吸附剂选择

室温下在实验装置上用工业吸附剂（活性炭、硅胶、氧化铝、沸石）对工业糠醛进行吸附干燥,测定出各种吸附剂的吸附容量及动态附量。在此条件下,糠醛的最大干燥程度在９３．５％～９８．２％之间。最有效的吸附剂是ＮａＡ型沸石,它以较高的动态吸附、较低的结焦性、较高的稳定性（２０个周期）优于其它工业吸附剂。     

关于颜色测量结果的修正

对在不同的测量仪器上测量同一颜色样品,测量结果不同的问题,利用颜色系统之间的线性变换原理及相对测量基准对测量结果进行修正,以提高测量结果之间的相互比对性．取两组马海毛纤维样品,每组６种试样,分别在两对颜色测量仪器上测量,应用线性变换原理,对测量结果的修正取得理想效果．     

紫蓬山区金腰燕繁殖生态研究

作者报道了1996年4－7月安徽紫蓬山区的金腰燕繁殖生态．结果表明,金腰燕4月初开始繁殖,巢营在室内檐下,窝卵数5．5枚,孵化期18天,育雏期28天,雏鸟体重增长的方程为     

Male-pattern baldness susceptibility locus at 20p11

We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)).     

MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

Disruption of signaling pathways such as those mediated by sonic hedgehog (Shh) or platelet-derived growth factor (Pdgf) causes craniofacial abnormalities, including cleft palate. The role that microRNAs play in modulating palatogenesis, however, is completely unknown. We show that, in zebrafish, the microRNA Mirn140 negatively regulates Pdgf signaling during palatal development, and we provide a mechanism for how disruption of Pdgf signaling causes palatal clefting. The pdgf receptor alpha (pdgfra) 3' UTR contained a Mirn140 binding site functioning in the negative regulation of Pdgfra protein levels in vivo. pdgfra mutants and Mirn140-injected embryos shared a range of facial defects, including clefting of the crest-derived cartilages that develop in the roof of the larval mouth. Concomitantly, the oral ectoderm beneath where these cartilages develop lost pitx2 and shha expression. Mirn140 modulated Pdgf-mediated attraction of cranial neural crest cells to the oral ectoderm, where crest-derived signals were necessary for oral ectodermal gene expression. Mirn140 loss of function elevated Pdgfra protein levels, altered palatal shape and caused neural crest cells to accumulate around the optic stalk, a source of the ligand Pdgfaa. These results suggest that the conserved regulatory interactions of mirn140 and pdgfra define an ancient mechanism of palatogenesis, and they provide candidate genes for cleft palate.     

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

Transitional cell carcinoma (TCC) is the most common type of bladder cancer. Here we sequenced the exomes of nine individuals with TCC and screened all the somatically mutated genes in a prevalence set of 88 additional individuals with TCC with different tumor stages and grades. In our study, we discovered a variety of genes previously unknown to be mutated in TCC. Notably, we identified genetic aberrations of the chromatin remodeling genes (UTX, MLL-MLL3, CREBBP-EP300, NCOR1, ARID1A and CHD6) in 59% of our 97 subjects with TCC. Of these genes, we showed UTX to be altered substantially more frequently in tumors of low stages and grades, highlighting its potential role in the classification and diagnosis of bladder cancer. Our results provide an overview of the genetic basis of TCC and suggest that aberration of chromatin regulation might be a hallmark of bladder cancer.     

城市轨道交通车站客流状态采集范围

随着城市化进程的不断推进,迅猛增加的轨道交通客流对客运组织管理提出了更高的要求.目前,虽然多样化的视频采集设备已广泛应用于地铁客流监测中,但是对视频监测范围缺乏统一的标准规范导致监控设备布设随意性大、客流采集无法满足监测需求,鉴于此,开展了对轨道交通车站客流状态数据采集范围的研究.首先,阐述了客流状态采集范围的概念和影...