Colchicine induced chromosomal interchange in castor beans (Ricinus communis linn.)

Zusammenfassung In mit Colchicin behandelten Pflanzen vonRicinus communis wurden neben tetraploiden Zellen auch solche mit Chromocomenbrüchen gefunden.     

Glutamate oxaloacetate transaminase (GOT) in thedy 2J genotypes of C57BL/6J mice: Possible involvement of regulatory defect in muscular dystrophy

Summary The GOT mitochondrial isozyme of heterozygote and homozygote muscular dystrophy (dy^2J) genotypes is affected during development prior to the expression of dystrophy in homozygotes, dy^2J/dy^2J.This research was supported by a Natural Science and Engineering Research Council Canada grant to S.M.S.     

Photodynamic inactivation and reversion inFusarium Species with Acriflavine

Zusammenfassung Es wird erstmals an einem Pilz gezeigt, dass auch beiFusarium infolge der inaktivierenden und mutagenen Wirkung von Acridinen zwischen einer photodynamischen Wirkung im Licht und einer schwächeren, auf anderen Mechanismen beruhenden Wirkung im Dunkeln unterschieden werden kann.     

Starling's law of the heart in cardiac and unstriated muscle killed by heat

Zusammenfassung Werden Magenmuskeln von Hund und Frosch oder Froschherzmuskeln bei 70°C Wärme denaturiert und auf 20°C abgekühlt, so zeigen sie eine relative Wärmekontraktion proportional zur Temperatur. Die auffallendste Erscheinung dieser Kontraktion ist, dass sie mit der Zunahme der initialen Länge zunimmt, und zwar entsprechend dem Verhalten der Kontraktion eines lebenden Muskels bei physiologischer Reizung.     

Iron alum as a mordant in cytology of Uredinales

Zusammenfassung Es wird ein Beizverfahren beschrieben, das sich bei der Färbung von Kernteilungsfiguren von keimenden Rotpilzsporen bewährt hat.     

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

Human apolipoprotein E has three isoforms: APOE2, APOE3 and APOE4. APOE4 is a major genetic risk factor for Alzheimer's disease and is associated with Down's syndrome dementia and poor neurological outcome after traumatic brain injury and haemorrhage. Neurovascular dysfunction is present in normal APOE4 carriers and individuals with APOE4-associated disorders. In mice, lack of Apoe leads to blood-brain barrier (BBB) breakdown, whereas APOE4 increases BBB susceptibility to injury. How APOE genotype affects brain microcirculation remains elusive. Using different APOE transgenic mice, including mice with ablation and/or inhibition of cyclophilin A (CypA), here we show that expression of APOE4 and lack of murine Apoe, but not APOE2 and APOE3, leads to BBB breakdown by activating a proinflammatory CypA-nuclear factor-κB-matrix-metalloproteinase-9 pathway in pericytes. This, in turn, leads to neuronal uptake of multiple blood-derived neurotoxic proteins, and microvascular and cerebral blood flow reductions. We show that the vascular defects in Apoe-deficient and APOE4-expressing mice precede neuronal dysfunction and can initiate neurodegenerative changes. Astrocyte-secreted APOE3, but not APOE4, suppressed the CypA-nuclear factor-κB-matrix-metalloproteinase-9 pathway in pericytes through a lipoprotein receptor. Our data suggest that CypA is a key target for treating APOE4-mediated neurovascular injury and the resulting neuronal dysfunction and degeneration.     

半胱氨酸亚金铵的合成、理化性质及电镀金应用

以半胱氨酸为配体合成一种新型亚金配合物NH4Au(Cys)2,对该配合物进行元素分析、红外光谱、紫外光谱、热失重分析和导电性测量等理化性质研究;以该亚金配合物为金源开展相关的电镀金工艺探索,并通过四因素三水平的正交试验获得其最佳条件参数;采用扫描电子显微镜(SEM)和X线衍射(XRD)对镀金层的表面质量进行探讨。研究结果表明:该目标产物的分子式为NH4Au(Cys)2·2H2O,该配合物中以半胱氨酸的巯基和金配位为成健特征,在170℃以下热稳定性较好,该亚金配合物是一个典型的离子化合物。在电流密度为200~300 A/m2,p H为10.5~12.0,温度为35~45℃,金质量浓度为15~25 g/L的电镀工艺条件下,得到粒度为0.5~1.0μm的单质金,且主要沿着(111)面进行生长。     

随机纳米碳管网络及其渗流性质

数值模拟了实验上构造纳米碳管网络的溶液沉积方法.与一般的随机网络模型不同,将碳管的长度计算在内,而且考虑了不同的空间相交位形.数值模拟发现网络的度分布为高斯分布,平均集聚系数约为0.11.当网络中碳管平均面密度取值在σ0=179 200根/cm2附近时,网络系综达到渗流.在临界点附近,网络的连通概率p、两极之间电导G、...     

Environmental Education: Enhancing Learning and Awareness Through Assessment

Environmental issues are rapidly gaining momentum globally as humans try to find sustainable solutions to the effects of climate change, carbon emissions, and the actions of human-kind (see Olver, Blacklist those who ‘greenwash’. Companies must walk the talk regarding climate. The Times, 2011a; The weather warriors’ war. Real change will come when a few good men and women say ‘enough is enough’. The Times, 2011b). To enhance learning and awareness of environmental issues among Environmental Education students and the community at large, this study situated assessments within communities of practice around the university. Using action engagement within action research students had to work with insiders from the community to identify, formulate action or intervention plans and find solutions to problem situations in the community. Using action engagement within action research in this study definitely enhanced student’s knowledge of their community’s problems. Their personal involvement and the cyclical approach adopted, enhanced students’ emotional understanding and gave them an insider perspective into the situations and problems that required intervention; and trust was built between the students and members of the community as they worked together to accomplish a common goal.