Pyrogen fever in rabbits pretreated with p-chlorophenylalanine or 5, 6-dihydroxytryptamine.

The hyperthermic effect of a bacterial pyrogen has been studied in rabbits pretreated or not with p-chlorophenylalanine or 5, 6-dihydroxytryptamine. The results obtained indicate that a selective reduction of cerebral 5-hydroxytryptamine levels by these drugs do not significantly affect pyrogen hypertermia.     

Effect of X-537A on the phosphorylated protein in sarcoplasmic reticulum vesicles

Summary The effect of the antibiotic X-537A on the phosphorylated ATPase (EP) was investigated. The results show that X-537A depresses the level of EP which is dependent on the Ca²⁺ gradient, while the Ca²⁺-independent EP is not affected. Acknowledgments. This work was supported by grants from the Instituto de Alta Cultura of the Portuguese Ministry of Education (No. CB/2) and the Calouste Gulbenkian Foundation.     

Blood plasma investigations by resonance raman spectroscopy: Detection of carotenoid pigments

Summary Using Raman spectroscopy, we demonstrate that low levels of -carotene, lycopene, and xanthophyll give rise to resonance enhanced bands in blood plasma. These results explain the significance of previously unidentified spectral maxima which have been related to the state of health of the blood donor.     

Struktur-Wirkungsbeziehungen beim menschlichen Calcitonin. III. Die biologische Aktivität verkürzter oder an den Kettenenden modifizierter,synthetischer analoger

Summary Assays of 8 synthetic analogues of human calcitonin in rats showed that their hypocalcaemic activity was drastically reduced by deletion of the C-terminal amide group, chain-shortening or opening of the disulphide ring, but unaffected or enhanced by modification of the N-terminal amino group.

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II. vgl.R. Maier, B. Kamber, B. Riniker andW. Rittel, Hormon. Metab. Res.7, 511 (1975).

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Die hier verwendete, abgekürzte Schreibweise für Peptide folgt den Empfehlungen der IUPAC-IUB Kommission für Biochemische Nomenklatur, J.B.C.247, 977 (1972). Weitere Abkürzungen: HCT, Human-Calcitonin; PCT, Schweinecalcitonin; Bmp, -Mercaptopropionsäure (Desaminocystein); NMet, Normethionin (S-Methylcystein); -OMe, Methylester.     

4-Isothiocyanato-4′-nitrodiphenylamine (C9333-Go/CGP 4540) an anthelminthic with an unusual spectrum of activity against intestinal nematodes,filariae and schistosomes

Summary 4-isothiocyanato-4-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird. Upon administration in a single oral dose it is equally effective againstS. haematobium, S. mansoni andS. japonicum.     

Ecdysone 20-hydroxylase from the midgut of the tobacco hornworm (Manduca sexta L.)

Summary An ecdysone 20-hydroxylase enzyme system that converts -ecdysone to 20-hydroxyecdysone was prepared from the midgut of the tobacco hornworm prepupa. This partially purified enzyme is NADPH dependent and is localized in the mitochondrial fraction of the midgut tissue.     

世界优秀男子110 m栏运动员成绩变化分析

采用文献资料调查、数理统计等科研方法, 对1997年世界田径锦标赛男子110 m栏前 7 名运动员的成绩进行相关分析, 揭示当今男子110 m栏全程速度变化的规律和特点, 并对近 4 年来世界优秀男子 110 m栏运动员与我国男子110 m栏运动员的成绩进行对比分析, 希望能对我国男子110 m栏的训练提供一些新的参考和启示.     

Holocene lake deposits of Bosten Lake, southern Xinjiang, China

A 9.25-m-long sediment core from Bosten Lake,Xinjiang, provides detailed information about changes in the water budget and biological acticity over the last 8400 cal-endar years. The chronology is constructed from six AMS radiocarbon dates on the terrestrial plant remains. Based onanalyses of TOC, CO3, detrital compounds and biogenic SiO2,lake level fluctuations and periods of remarkably-negative water budget appeared at 8.4-8.2 cal ka, 7.38-7.25 cal ka,5.7-5.5 cal ka, 3.7-3.4 cal ka and 3.3-2.9 cal ka, respec-tively. As they are in-phase with low lake levels at Sumxl Co and Bangong Co in western Tibet Plateau and with paleo-lakes in Inner Mongolia, a climate-induced change to some-what drier and warmer conditions is inferred. A further drop in lake level after 1320 AD of about 200 yr duration may heattributed to a negative water balance prior to the main phase of the Little Ice Age. Deep and stable lake phases of 1500 yr and 1800 yr duration at 7.2-5.7 cal ka and 5.5-3.7cal ka coincide with maximum moisture during the Holocene Megathermai in China. The long term trend towards aridity since about 4.3 cal ka can dearly be recognised. The reduced water budget of Bosten Lake from 640-1200 AD may be attributed to local effects.     

Ni2MnGa铁磁形状记忆材料

铁磁形状记忆合金 (FSMA)是在一定温度范围马氏体相稳定同时又具铁磁性的一类特殊的形状记忆合金。Ni2MnGa铁磁形状记忆合金近年来成为呈现磁场驱动大应变的新型驱动材料 ,这些应变来自磁场诱发马氏体孪晶的重排 ,而不是磁场对奥氏体至马氏体相变的作用。孪晶变体的重排在宏观上呈现为正或切应变 ,一非化学计量比Ni2 MnGa单晶于室温加 0 .4T磁场能产生6 %的应变 ,Ni Mn Ga单晶在高至 15 0Hz的交变磁场仍可得到 2 .5 %的应变。本文阐述了与这种磁控形状记忆效应相关的孪晶界迁动的磁学和晶体学理论。马氏体相的大磁晶各向异性能使磁化沿c轴方向有利 ,穿过孪晶界c轴刚好转动 90度 ,同时 ,这个孪晶界也构成了约 90度的畴界。在各向异性的情况下 ,孪晶界的迁动仅有相邻孪晶变体的Zeeman能差驱动 ,μ0 ΔMis·Hi。磁场和外应力对应变的影响通过对一简单的自由能表达式取极小值来表示 ,自由能表达式包括Zeeman能、磁晶各向异性能和外应力以及在某些情况下需考虑的内部弹性能 ,模型的所有参数可通过应力 应变曲线和磁化曲线测量得到。铁磁形状记忆合金的磁场诱发应变可类比传统热弹性形状记忆效应 ,与更为人们所熟知的磁致伸缩现象不同。