Al-Cu-Fe-Zn系准晶的形成规律研究

本文通过快速冷凝方法制得了Al-Cu-Fe-Zn系合金粉末。这种快冷合金粉末在室温下为准晶相和晶态相共存结构,当把粉末加热到773K左右时,晶态相开始消失并且转变为准晶相,加热到1000K晶态相基本上完全转变为准晶相,继续升温准晶相又逐渐减少,晶态相重新产生和增加。本文对Al-Cu-Fe-Zn系快冷合金粉末的加热相变、准晶形成规律、准晶的成分范围进行了详细的研究。     

钻软硬交错地层时钻头弯矩及转角的计算方法

本文详细地分析了从软地层钻入硬地层前后,钻头上产生弯矩的原因及计算方法。根据软硬地层的可钻性不同,钻速及相应的地层对钻头的反作用力也不同的原理,推导了在钻过交界面前后钻头的转角、钻具的反力矩及软硬地层中不同钻速与时间的关系式及微分方程,给出了方程的解。求解结果表明,钻头的转角和弯矩是随时间的延长而逐渐增大,在全部钻完交界面时达到最大值;钻头弯矩与交错层的可钻性、下部钻具的结构和钻头的几何尺寸有关,并且与所加的钻压成正比。     

普宁明华体育馆的声学设计

本文对普宁明华体育馆的建声和电声进行了统一设计．其中的一些设计思想对其他中型多功能体育馆也有参考价值．     

Bifurcation and chaos of the bladed overhang rotor system with squeeze film dampers

To study the nonlinear dynamic behavior of the bladed overhang rotor system with squeeze film damper (SFD),a blade-overhang rotor-SFD model is formulated using the lumped mass method and the Lagrange approach.The cavitated short bearing model is employed to describe the nonlinear oil force of the SFD.To reduce the scale of the nonlinear coupling system,a set of orthogonal transformations is employed to decouple the one nodal diameter equations of blades,which are coupled with the dynamical equations of the ...     

Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration

We defined the genetic landscape of balanced chromosomal rearrangements at nucleotide resolution by sequencing 141 breakpoints from cytogenetically interpreted translocations and inversions. We confirm that the recently described phenomenon of 'chromothripsis' (massive chromosomal shattering and reorganization) is not unique to cancer cells but also occurs in the germline, where it can resolve to a relatively balanced state with frequent inversions. We detected a high incidence of complex rearrangements (19.2%) and substantially less reliance on microhomology (31%) than previously observed in benign copy-number variants (CNVs). We compared these results to experimentally generated DNA breakage-repair by sequencing seven transgenic animals, revealing extensive rearrangement of the transgene and host genome with similar complexity to human germline alterations. Inversion was the most common rearrangement, suggesting that a combined mechanism involving template switching and non-homologous repair mediates the formation of balanced complex rearrangements that are viable, stably replicated and transmitted unaltered to subsequent generations.     

一个机械手臂系统的键图模型及其仿真

键图模型是描述动态系统的一种新的图示模型。该文采用这个方法建立了一个简单机械手臂系统的模型。方法简单,仿真结果表明该方法在非线性系统建模中应用的可行性及可推广性。     

Examination of dynamic recrystallization during compression of AZ31 magnesium

This study aimed to investigate dynamic recrystallization(DRX)behavior during compression of magnesium alloy AZ31. Cylinder samples were cut from the extruded rod and hot rolled sheet AZ31 for compression test.The samples were compressed using a Gleeble 1500D at a temperature of 300℃and a strain rate of 0.01 s-1.Grain orientations and misorientation angles across grain boundaries for the tested samples were obtained by using electron backscatter diffraction(EBSD)technique.The results showed that strong basal texture was observed after 50%compression(ε=0.69)on both the extruded and hot rolled samples,which have different initial textures.It was observed that with increased strain,DRX grains gradually rotated to basal orientation,and grain boundaries with misorientation angle of near 30°was formed in the samples.At the strain of 0.69,a high fraction of high-angle(60°)boundaries was present in the extruded sample,whereas almost no high angle boundaries were observed in the hot rolled sheet sample.     

Treatment of PC-3 cells with ultrasound combined with microbubbles induces distinct alterations in the expression of Bcl-2 and Bax

The objective of the present study was to investigate whether ultrasound combined with microbubbles induces apoptotic cell death in androgen-independent prostate cancer cells and to identify the probable mechanism. We used ultrasound in continuous wave mode with a frequency of 21 kHz and a spatial-average temporal-average intensity of 46 mW/cm². Ultrasound combined with microbubbles (200 μL SonoVue?) was used to treat androgen-independent human prostate cancer PC-3 cells for 30 s. PC-3 cells were divided into three groups: the control group, the ultrasound group and the ultrasound combined with microbubbles group. Immediately after treatment, trypan blue exclusion was used to assess cell viability. Cell apoptosis at 24 h after treatment was measured using transmission electron microscopy and flow cytometry. Western blotting was used to evaluate the expression of the apoptosis-related proteins, Bcl-2 and Bax. Ultrasound combined with microbubbles had a minimal effect on the viability of PC-3 cells and induced minimal levels of cell lysis. The level of apoptosis in PC-3 cells induced by this modality was significantly higher than in controls (12.77 ± 0.31% vs. 2.56 ± 0.22%, P<0.01). Treatment with ultrasound combined with microbubbles increased the expression of Bax, a pro-apoptotic protein, and decreased the expression of Bcl-2, an anti-apoptotic protein. It was concluded that ultrasound combined with microbubbles induces apoptotic cell death in human prostate cancer PC-3 cells through down-regulation of Bcl-2 and up-regulation of Bax.     

求解最小覆盖问题的快速近似算法的进一步研究

分析了已有求覆盖平面上给定的若干个点的尽可能小的圆的问题的算法。给出了一个新的求解最小覆盖问题的算法，其计算时间复杂度为平面上给定的点数量的线性函数，该算法已编程实现，通过几万例随机算例的实际计算比较，表明算法所得结果的平均精度比已有的各种快速近似算法所得的精度要高，而且具体每例所需的计算时间均比已有快速近似算法对应的计算时间要短。     

Si基片各向异性腐蚀特性研究

为了制备高性能铁电薄膜红外探测器 ,对Si微桥的湿化学腐蚀工艺进行了研究 .利用Si基片各向异性腐蚀特性 ,在四甲基氢氧化铵 (简称TMAH )水溶液中加入氢氧化钾 (KOH)作为各向异性腐蚀液 (简称KTMAH) ,研究了TMAH与KOH摩尔比、腐蚀浓度、腐蚀温度对Si基片腐蚀特性的影响 .结果表明 :Si(1 0 0 )面的腐蚀速度随着腐蚀液浓度和温度的升高而增大 ,随着TMAH与KOH摩尔比的降低 ,KTMAH腐蚀液对掩膜层的腐蚀程度加剧 .选用 5 g/L的过硫酸盐 (PDS)与TMAH质量分数为 2 5 %、TMAH与KOH摩尔比为2的KTMAH混合液作为腐蚀液 ,并在 80℃× 2 .5h的腐蚀条件下能得到平整的腐蚀面 ,可以制备质量较好的微桥结构