函数极限与积分可交换的一个充分条件

研究了函数极限与积分可交换的问题，利用了平均一致收敛的定义，给出了一个比一致（R）可积性弱的充分条件。     

Generation of Linear and Parabolic Concentration Gradients by Using a Christmas Tree-Shaped Microfluidic Network

This paper describes a simple method of generating concentration gradients with linear and parabolic profiles by using a Christmas tree-shaped microfluidic network.The microfluidic gradient generator consists of two parts:a Christmas tree-shaped network for gradient generation and a broad microchannel for detection.A two-dimensional model was built to analyze the flow field and the mass transfer in the microfluidic network.The simulating results show that a series of linear and parabolic gradient profiles were generated via adjusting relative flow rate ratios of the two source solutions(R_L~2≥0.995 and _PR~2≥0.999),which could match well with the experimental results(R_L~2≥0.987 and _PR~2≥0.996).The proposed method is promising for the generation of linear and parabolic concentration gradient profiles,with the potential in chemical and biological applications such as combinatorial chemistry synthesis,stem cell differentiation or cytotoxicity assays.     

面向对象图形用户界面的设计与实现

在分析计算机用户界面开发方法和工具的基础上，提出了利用对象模型化技术开发图形用户界面的思想。根据此思想，设计并实现了一个面向对象的图形用户界面（ＧＵＩ）。     

普宁明华体育馆的声学设计

本文对普宁明华体育馆的建声和电声进行了统一设计．其中的一些设计思想对其他中型多功能体育馆也有参考价值．     

Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration

We defined the genetic landscape of balanced chromosomal rearrangements at nucleotide resolution by sequencing 141 breakpoints from cytogenetically interpreted translocations and inversions. We confirm that the recently described phenomenon of 'chromothripsis' (massive chromosomal shattering and reorganization) is not unique to cancer cells but also occurs in the germline, where it can resolve to a relatively balanced state with frequent inversions. We detected a high incidence of complex rearrangements (19.2%) and substantially less reliance on microhomology (31%) than previously observed in benign copy-number variants (CNVs). We compared these results to experimentally generated DNA breakage-repair by sequencing seven transgenic animals, revealing extensive rearrangement of the transgene and host genome with similar complexity to human germline alterations. Inversion was the most common rearrangement, suggesting that a combined mechanism involving template switching and non-homologous repair mediates the formation of balanced complex rearrangements that are viable, stably replicated and transmitted unaltered to subsequent generations.     

含多重临界位势的渐近线性椭圆方程的正解

在新Sobolev-Hardy空间中讨论含多重临界位势的渐近线性椭圆方程正解的存在性.该方程的非线性项是渐近线性的,不满足Ambrosetti-Rabinowitz条件.文中运用没有Palais-Smale条件的山路引理证明了在较弱的条件下,方程至少存在一个正解.     

Treatment of PC-3 cells with ultrasound combined with microbubbles induces distinct alterations in the expression of Bcl-2 and Bax

The objective of the present study was to investigate whether ultrasound combined with microbubbles induces apoptotic cell death in androgen-independent prostate cancer cells and to identify the probable mechanism. We used ultrasound in continuous wave mode with a frequency of 21 kHz and a spatial-average temporal-average intensity of 46 mW/cm². Ultrasound combined with microbubbles (200 μL SonoVue?) was used to treat androgen-independent human prostate cancer PC-3 cells for 30 s. PC-3 cells were divided into three groups: the control group, the ultrasound group and the ultrasound combined with microbubbles group. Immediately after treatment, trypan blue exclusion was used to assess cell viability. Cell apoptosis at 24 h after treatment was measured using transmission electron microscopy and flow cytometry. Western blotting was used to evaluate the expression of the apoptosis-related proteins, Bcl-2 and Bax. Ultrasound combined with microbubbles had a minimal effect on the viability of PC-3 cells and induced minimal levels of cell lysis. The level of apoptosis in PC-3 cells induced by this modality was significantly higher than in controls (12.77 ± 0.31% vs. 2.56 ± 0.22%, P<0.01). Treatment with ultrasound combined with microbubbles increased the expression of Bax, a pro-apoptotic protein, and decreased the expression of Bcl-2, an anti-apoptotic protein. It was concluded that ultrasound combined with microbubbles induces apoptotic cell death in human prostate cancer PC-3 cells through down-regulation of Bcl-2 and up-regulation of Bax.     

Szász-Durrmeyer算子在Orlicz空间中的加权逼近

在Orlicz空间LM中讨论了Szász-Durrmeyer算子的加权逼近,得到了逼近阶的Jackson型估计.     

干湿交替对湖滨带不同高程沉积物磷释放的影响研究

湖水水位变化引起的湖滨带沉积物干湿交替过程显著地影响着磷的迁移转化,本文以贡湖湖滨带为对象,研究湖滨带最高水位沉积物与低位淹水沉积物对磷的吸附解吸能力及再淹水过程中磷释放量。研究发现,湖滨带高位沉积物与淹水沉积物相比黏土级颗粒含量较低,中位粒径较大,湖滨带高位沉积物对磷的吸附能力弱于淹水沉积物。淹水后湖滨带高位沉积物TP释放量高于淹水沉积物,沉积物释磷以Ca-P形态为主,随着湖滨带沉积物由高到低,Ca-P释放量逐渐下降。     

Design and fabrication of 1-D semiconductor nanomaterials for high-performance photovoltaics

To date, the cost-effective utilization of solar energy by photovoltaics for large-scale deployment remains challenging. Further cost minimization and efficiency maximization, through reduction of material consumption, simplification of device fabrication as well as optimization of device structure and geometry, are required. The usage of 1D nanomaterials is attractive due to the outstanding light coupling effect, the ease of fabrication, and integration with one-dimensional(1-D) semiconductor materials. The light absorption efficiency can be enhanced significantly, and the corresponding light-toelectricity conversion efficiency can be as high as their bulk counterparts. Also, the amount of active materials used can be reduced. This review summarizes the recent development of 1-D nanomaterials for photovoltaic applications, including the anti-reflection, the light absorption,the minority diffusion, and the semiconductor junction properties. With solid progress and prospect shown in the past 10 years, 1-D semiconductor nanomaterials are attractive and promising for the realization of high-efficiency and low-cost solar cells.