遗传学立体化教材的建设与研究

为适应现代遗传学的学科发展,促进高校生物创新人才的培养,变革高校传统的遗传学教材体系和教学模式已势在必行.在探究教学环节的过程中,针对目前高校遗传学教学中存在的普遍性问题,提出建设遗传学立体化教材,实施立体化的教学模式.本文主要从遗传学主教材的构建、多媒体课件的制作、学习指导书的编订以及试题库的建设等方面详细探讨这一新的教材体系的建设模式及其初步实践效果.     

网格化工商业市场监管系统设计与实现

介绍网格化工商市场监管系统的设计,采用分布式数据库结构,C/S与B/S相结合,实现了对企业监管的网格化、分级式管理,包括企业注册登记、企业信用等级监管、用户投诉与审核、企业荣誉与处罚等功能.     

具有4个传输零点的源-负载耦合滤波器

为了得到高选择性、小尺寸、低损耗和低成本的射频带通滤波器,提出了一种具有4个传输零点的源–负载耦合滤波器的设计方法.该滤波器采用二分之一波长T形多模谐振器,以减小滤波器尺寸和方便带宽设计.同时,根据信号的多路径传输产生零点原理,在滤波器的输入和输出端口之间加入可控耦合元件,为信号的传输提供多条路径,使得该滤波器可产生4个独立于带宽和中心频率的可控零点.文中最后设计和制作了一个带内最小测量插损为1.4dB、相对带宽为10%、具有4个传输零点的小型微带滤波器,并对其进行了测试,测试结果与仿真结果吻合良好,说明这种设计方法是有效的.     

Discovery and significance of buried paleoearthquake of the early Shang Dynasty (1260–1520 BC) in Xuecun, Xingyang, Henan Province, China

Due to the South-to-North Water Diversion Project,the salvage archaeological excavations were conducted in Xuecun,Xingyang city,Henan Province,China,by the Institute of Cultural Relics and Archaeology of Henan Province in 2005 and 2006.Ample evidence for a paleoearthquake was found during the excavation in the Xuecun archaeological site.The evidence includes faults,two small grabens and a series of ground fissures.These geological structures are considered to be generated by the earthquake.Based on the rela...     

Quantitative reactivity profiling predicts functional cysteines in proteomes

Cysteine is the most intrinsically nucleophilic amino acid in proteins, where its reactivity is tuned to perform diverse biochemical functions. The absence of a consensus sequence that defines functional cysteines in proteins has hindered their discovery and characterization. Here we describe a proteomics method to profile quantitatively the intrinsic reactivity of cysteine residues en masse directly in native biological systems. Hyper-reactivity was a rare feature among cysteines and it was found to specify a wide range of activities, including nucleophilic and reductive catalysis and sites of oxidative modification. Hyper-reactive cysteines were identified in several proteins of uncharacterized function, including a residue conserved across eukaryotic phylogeny that we show is required for yeast viability and is involved in iron-sulphur protein biogenesis. We also demonstrate that quantitative reactivity profiling can form the basis for screening and functional assignment of cysteines in computationally designed proteins, where it discriminated catalytically active from inactive cysteine hydrolase designs.     

混凝土中结合氯离子研究综述

混凝土中氯离子的结合会影响其侵蚀进程。且结合氯离子并不稳定,在酸化、碳化、化学侵蚀与通电作用等情况下会失稳释放,从水泥结合氯离子的机理、结合能力及结合氯离子稳定性等方面对中外研究现状进行综述。提出了对于某些因素需要建立更合理的评价标准,需要深入研究多因素耦合作用及降低失稳氯离子对钢筋腐蚀危害的研究建议。     

基于正交设计试验的双锥药型罩结构优化

双锥药型罩成形的影响因素复杂,其壁厚、上锥角、下锥角以及上锥高度占比4个参数对形成射流的特性、侵彻性能产生重要影响。基于正交设计方法分析以上因素对射流特性及侵彻能力的影响。选取双锥药型罩的以上4个参数为正交优化的4个因素,将射流头部速度、速度梯度以及有效长度作为优化时主要的评价指标,对双锥药型罩进行结构方案优化。通过分析双锥药型罩数值仿真优化结果,得到药型罩上锥角为25°、下锥角为55°、壁厚为3.5 mm、上锥占比60%时,其形成的射流具有较好的破甲效果。     

Effects of thermomechanical treatments on the microstructures and mechanical properties of GTA-welded AZ31B magnesium alloy

Thermomechanical treatments were carried out to improve the properties of AZ31B joints prepared by gas tungsten arc welding. The microstructures of the joints were studied by optical microscopy and scanning electron microscopy with energy-dispersive spectrometry. Tensile tests and hardness tests were performed to investigate the effects of thermomechanical treatments on the mechanical properties of the joints. It is found that the thermomechanical-treated joints show superior mechanical properties against the as-welded joints, and their ultimate tensile strength can reach more than 92% of the base material. This mainly attributes to the formation of fine equiaxed grains in the fusion zone. After thermomechanical treatments the dendrites are transformed to fine spherical grains, and the dendritic segregation can be effectively eliminated.     

应用光学原理研究原油沥青的聚沉过程

利用Turbiscan Lab 稳定性分析仪研究了原油/甲苯混合体系的稳定性。将不同加量的沉淀剂应用于1：9 的原油/甲苯混合体系中,通过测量原油/甲苯的透射光和背散射光强度随时间的变化,可描述混合体系中沥青的聚集和沉淀过程,有助于分析原油不稳定性发生的机理,并定量分析了沥青聚沉过程中的颗粒粒径大小、粒径增大速率和颗粒沉降速率等。实验表明,随着沉淀剂的加量从80.0% 增加到90.9%,混合体系中沥青的聚集速率从192.216 μm/min 增加到5 332.120 μm/min,粒径从10.0 μm 增大为53.4 μm ,沉积速率从0.17 mm/min 增加到0.46 mm/min。     

巨厚砾岩下开采地表沉陷预计模型的改进

为了探究巨厚砾岩下开采的地表沉陷规律,结合关键层理论,通过数值模拟从垂直应力、塑性区、垂直位移3个方面分析覆岩内部稳定性及造成地表倾向下沉曲线偏态的原因,基于概率积分法,建立改进的地表沉陷预计模型。结果表明:关键层初次破断距为291 m,周期破断距为281 m;悬力臂是造成下沉曲线偏态的主要原因;相对于经典的概率积分沉陷预计模型,改进的地表沉陷预计模型相对误差减小114%。可见在巨厚砾岩层下开采地表沉陷预计中,改进的地表沉降预计模型具有较高的准确度和适用性。