地面防空作战效能的模糊综合评价

地面防空兵是我军重要的防空力量,长期以来其作战效能的评价都采用单一的指标,无法全面、准确地进行评价.通过对影响地面防空作战效能各因素的全面分析,建立了作战效能综合评判的指标体系,给出了作战效能评价模型和评价方法,介绍了运用层次分析法确定各因素权重的方法,并进行了实例分析.研究成果对全面而科学地评价地面防空兵作战效能具有积极的指导作用和较强的实用性.     

Sulfatide-tenascin interaction mediates binding to the extracellular matrix and endocytic uptake of liposomes in glioma cells

Tenascin-C is an extracellular matrix glycoprotein, whose expression is highly restricted in normal adult tissues, but markedly up-regulated in a range of tumors, and therefore serves as a potential receptor for targeted anticancer drug or gene delivery. We describe here a liposomal carrier system in which the targeting ligand is sulfatide. Experiments with tenascin-C-expressing glioma cells demonstrated that binding of liposomes to the extracellular matrix relied essentially on the sulfatide-tenascin-C interaction. Following binding to the extracellular matrix, the sulfatide-containing liposomes were internalized via both caveolae/lipid raft- and clathrin-dependent pathways, which would ensure direct cytoplasmic release of the cargoes carried in the liposomes. Such natural lipid-guided intracellular delivery targeting at the extracellular matrix glycoproteins of tumor cells thus opens a new direction for development of more effective anticancer chemotherapeutics in future. K. Shao & Q. Hou: These authors contributed equally to this work. Received 22 September 2006; received after revision 5 December 2006; accepted 9 January 2007     

The NCBI dbGaP database of genotypes and phenotypes

The National Center for Biotechnology Information has created the dbGaP public repository for individual-level phenotype, exposure, genotype and sequence data and the associations between them. dbGaP assigns stable, unique identifiers to studies and subsets of information from those studies, including documents, individual phenotypic variables, tables of trait data, sets of genotype data, computed phenotype-genotype associations, and groups of study subjects who have given similar consents for use of their data.     

考虑供应商聚类的应急医疗物资协同配送仿真

针对突发公共卫生事件应急处置中存在的地方政府医疗物资储备不足、配送效率低下等问题,设计了一种考虑供应商聚类的两阶段应急医疗物资公私协同选址分配模型。在备灾时利用模糊聚类算法实现供应商聚类,并与政府建立合作机制以实现应急医疗物资联合储备;在救援初期依托政府和各类供应商的物资储备及运输能力,构建以最小化物流总成本与需求未满足率加权和为目标的选址分配仿真模型。设计改进的非支配排序遗传算法对此两阶段模型进行求解。以新冠肺炎疫情中武汉市医疗物资调度设计仿真算例,并对比有无供应商聚类对模型的影响。仿真结果表明：该模型在协调政府和供应商的应急医疗物资储备、运输以及调度决策方面具有优势。     

剃前滚刀齿形误差的分析

本文分析了拟合曲线、安装参数、切削过程、造型原理与设计精度等对剃前滚刀齿形误差的影响,此分析将有助于提高剃前滚刀齿形的设计与加工精度。     

论企业的稳步发展需提高自主创新能力

通过阐述自主创新的必要性和紧迫性,进一步具体指出应从哪些方面如何提高自主创新的能力.才能立足于创新型国家的行列.企业才能又快又好地稳步发展.     

Adaptive bit and power loading algorithm with low complexity in MIMO-OFDM systems

Two adaptive power and bit loading algorithms to maximize the throughput of MIMO-OFDM systems in frequency selective fading environment are proposed. The two algorithms allocate bit based on maximizing the overall throughput. One algorithm allocates power based on guaranteeing that the bit error rate （BER） of each sub-carrier and the total allocated power remain below a target BER threshold and a power threshold, respectively; another one allocates power based on guaranteeing that the mean BER of sub-carriers and the total allocated power remain below a target BER threshold and a power threshold, respectively. The simulation results show that the proposed algorithms can achieve faster throughput with lower computational complexity, which indicates that the proposed algorithms are effective when compared to some existing algorithms.     

生物压电陶瓷复活种植材料研究

从HABT陶瓷的电性能测试及对定向基片上细胞生长率的观察,确认它具有合适的压电性能诱导骨细胞生长.生物学性能检测表明HABT陶瓷无毒,适合于作生物种植材料.     

激励误差对子阵阵列天线副瓣电平的影响

对于含有激励误差的由子阵组成的平面阵列天线,本文推导了当子阵尺寸不同而且在子阵中采用行馈或列馈馈电方式时,波瓣的方差及主平面内峰值副瓣概率的计算公式,并在三种激励幅相误差的条件下,对主平面内峰值副瓣概率的理论值与统计值作了比较,结果相当一致。