量子力学的经典极限与库仑散射

论述了量子力学的经典极限问题,并运用狄拉克判据研究了库仑散射的经典极限;指出库仑散射存在一经典极限的“黑箱”禁区,在经典极限的“黑箱”禁区以外,库仑散射的经典理论是量子理论的很好近似。     

二(1-苯基-3-甲基-4-苯甲酰吡唑啉酮-5)合钯(Ⅱ)的热分解机理

报道了二（１－苯基－３－甲基－４－苯甲酰吡唑啉酮－５）合钯（Ⅱ）的合成、红外表征及非等温热分解动力学．采用微分和积分相结合的方法,推断出了可能的热分解机理及热力学方程．     

基于地磁定轨和扩维卡尔曼滤波的导航算法

为了克服扩展卡尔曼 (Kalman)滤波算法对噪声统计特性的约束 ,针对磁强计量测噪声为有色噪声伴常值干扰的特性 ,提出了一种基于扩维Kalman滤波算法的地磁导航算法 .该算法为了使量测噪声白噪化 ,引入了 2个新的状态变量 ,此时测量噪声是均值为 0的高斯白噪声 ,并满足扩展Kalman滤波算法的约束条件 .对由此构成的系统使用扩展Kalman滤波算法 ,可以得到扩维Kalman定轨导航算法 ,利用该算法可以获得国产磁强计的导航精度 ,其地心距模的估计误差为 2 0km ,速度模的估计误差为 10m/s .卫星的实测数据仿真结果表明 ,该导航算法具有较好的稳定性和收敛性 ,克服了扩展Kalman滤波算法的发散问题     

Preparation of the selenomethionine derivative of tabtoxin resistance protein

In order to obtain phase information for the X-ray diffraction of tabtoxin resistance protein (TTR) crystal using the MAD phasing method, a selenomethionine (Se-Met) derivative of TTR was overexpressed in E. coli strain M15, with pQE-30 plasmid, through IPTG induction in M9 medium containing Se-Met. The product was purified to an estimated homogeneity of greater than 95% according to SDS-PAGE, by a Ni-NTA metal affinity followed by a Mono Q anion exchange column chromatography. The successful substitution of Se-Met for methionine (Met) was confirmed by MALDI-TOF and ESI-Quadrupole Mass Spectrometry analysis. The derivative crystal was obtained using similar conditions as those for the native.     

神经网络的遗传设计及其在甲醛生产建模及优化中的应用

采用遗传算法的机制设计了一种同时对前向网络的连接权值及拓扑结构进行搜索的方法，并采用以隐结点为基本基因型的方式，同时在算法中加入了局部搜索的方法．该算法已被应用于甲醛生产过程的建模及优化，达到了良好的效果．     

填充氩后单壁碳纳米管的导热系数

采用平衡态分子动力学(EMD)模拟方法,计算了填充氩后的(10,10)型和(15,15)型的单壁碳纳米管分别在不同温度下的导热系数.研究了它们随温度的变化情况,并将其与相应的空的碳纳米管的导热系数进行比较,分析在相同温度下,充氩对碳纳米管导热系数的影响.模拟结果发现:在500~1 200 K的温度范围内,(10,10)型碳纳米管和(15,15)型碳纳米管在填充了氩后其导热系数值均随着温度的升高呈下降趋势,这与空的碳纳米管的导热系数随温度的变化关系相似;在相同温度下,这2种类型的碳纳米管在填充了氩后的导热系数值均比相应的空的碳纳米管的导热系数值明显高很多.     

Lidamycin inhibits tumor growth and pulmonary metastasis in murine breast carcinoma and shows synergy with paclitaxel

The main goal of this study was to investigate whether lidamycin (LDM) could enhance the efficacy of paclitaxel (TAX) against breast cancer. In the MTT assay, LDM showed much more potent cytotoxicity than paclitaxel, and there was a synergy on the 4T1/luc breast cancer cells treated with a combination of paclitaxel and LDM. Western blot analysis showed that paclitaxel and LDM synergistically downregulated MMP9, MMP2, VEGF, and upregulated the cleaved PARP proteins. By wound closure cell migration assay, paclitaxel combined LDM obviously inhibited the migration of 4T1/luc cells. At therapeutic dosage level, LDM, paclitaxel, and the combination suppressed the pulmonary metastases by 70.2%, 53.8%, and 88.7%, respectively, and the CDI value was 0.82, indicating synergism. The results show that LDM enhances the antitumor effect of paclitaxel on 4T1/luc breast cancer, in particular, the antimetastatic effects on pulmonary metastasis.     

奶牛乳房炎的病因分析

对引起奶牛乳房炎的病原微生物，包括接触传染性病原菌和环境性病原菌的种类及症状做了阐述与分析。     

多目标混流装配计划排序问题

在总结混流装配线排序问题的优化目标基础上,给出了一种混流装配线排序多目标优化模型.采用一种染色体映射的策略,有效地解决了遗传算法中染色体变化后难以保证主生产计划约束的问题.对比计算的结果表明:多目标计划排序不仅能有效保证基于生产负荷平衡的目标和基于物流平顺化的目标的要求,同时还能减少装配中品种切换频繁的问题.     

超声波振动切削时振动刀具对工件的冲击作用

通过实验,明确了影响振动切削效果的主要因素,认清了超声振动切削对切削过程所起的作用。推导出振动刀具与回转工件在接触瞬间产生碰撞的功能损失公式,并对该能量在切削过程中所起的作用及获得最佳效果所需要的条件进行了研究。