对称三腔GaInAsP/InP单模激光器

为实现长距离、大容量、高质量的信号传输,必有高性能动态单模激光器作为光源。目前这种器件主要有DBR和DFB激光器,复合腔激光器,短腔激光器,外腔及注入锁定激光器。本文报导了一种对称三段复合腔激光器的制备和选模特性。     

农业物料流化床中颗粒偏析运动的随机微分方程

本文在研究农业物料流化床中颗粒沿铅垂方向的偏析运动时,用概率的方法对影响运动最主要的随机因素——颗粒间的碰撞作用进行描述,在此基础上建立了床中颗粒沿铅垂方向偏析运动的随机微分方程,并对求解方法进行了初步的探讨。另外,还对部分农业物料流化床的表观粘度、床中颗粒的扩散系数进行了测定,从而为流化偏析现象的实际应用和进一步研究打下了一定的理论基础。     

CuZnAl形状记忆合金时效过程研究

铜基形状记忆合金的时效是影响其应用的关键之一。对ＣｕＺｎＡｌ形状记忆合金 时效过程的研究表明：在 ２９３～３７３Ｋ温度范围内时效，随时效温度的提高．马氏体 相向母相转变的温度变化值减小．时效作用减弱；母相保温可使相变点稳定；造成 ＣｕＺｎＡｌ形状记忆合金时效的一个重要原因是淬火过饱和空位的偏聚。     

一维拟线性波动方程带耗散边界条件的第三边值问题

本文对一维拟线性波动方程带耗散边界条件的第三边值问题(?) 在边界耗散适当大的条件下证明了若初值的C~2模适当小,则存在唯一的整体C~2解。     

金属冲击加热的研究

金属冲击加热是对流快速加热的一种新型加热工艺,也是金属加热的一项节能新技术。它是用高温高速气流直接冲击金属表面的快速对流加热方法来完成金属锻前或轧前的加热,金属加热温度均匀、加热速度快、加热时间短,可以大大降低燃耗。本文由金属冲击加热数学模型,用计算机解出了获得最佳加热炉温和断面温差最小的加热时间时换热系数范围为:300～500KKal/m~2·h·℃     

Cloning of a probable potassium channel gene from mouse brain

Potassium channels comprise a diverse class of ion channels important for neuronal excitability and plasticity. The recent cloning of the Shaker locus from Drosophila melanogaster has provided a starting point for molecular studies of potassium channels. Predicted Shaker proteins appear to be integral membrane proteins and have a sequence similar to the sequence of the S4 segment of the vertebrate sodium channel, where the S4 segment has been proposed to be the voltage sensor. Expression studies in frog oocytes confirm that Shaker encodes a component of a potassium channel (the A channel) that conducts a fast transient potassium current. Here we report the isolation of complementary DNA clones from the mouse brain, the nucleotide sequences of which predict a protein remarkably similar to the Shaker protein. The strong conservation of the predicted protein sequence in flies and mammals suggests that these mouse clones encode a potassium channel component and that the conserved amino acids may be essential to some aspect of potassium channel function.     

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

Alzheimer's disease is characterized by cerebral deposits of amyloid beta-protein (AP) as senile plaque core and vascular amyloid, and a complementary DNA encoding a precursor of this protein (APP) has been cloned from human brain. From a cDNA library of a human glioblastoma cell line, we have isolated a cDNA identical to that previously reported, together with a new cDNA which contains a 225-nucleotide insert. The sequence of the 56 amino acids at the N-terminal of the protein deduced from this insert is highly homologous to the basic trypsin inhibitor family, and the lysate from COS-1 cells transfected with the longer APP cDNA showed an increased inhibition of trypsin activity. Partial sequencing of the genomic DNA encoding APP showed that the 225 nucleotides are located in two exons. At least three messenger RNA species, apparently transcribed from a single APP gene by alternative splicing, were found in human brain. We suggest that protease inhibition by the longer APP(s) could be related to aberrant APP catabolism.     

Brain-derived neurotrophic factor prevents neuronal death in vivo

Developing vertebrate neurons are thought to depend for their survival on specific neurotrophic proteins present in their target fields. The limited availability of these proteins does not allow the survival of all neurons initially innervating a target, resulting in the widely observed phenomenon of naturally occurring neuronal death. Although a variety of proteins have been reported to promote the survival of neurons in tissue culture, the demonstration that these proteins increase neuronal numbers and/or decrease neuronal death in vivo has only been possible with nerve growth factor (NGF). The generalization of the concept that neurotrophic proteins regulate neuronal survival during normal development critically depends on the demonstration that the survival of neurons in vivo can be increased by the administration of a neurotrophic protein different from NGF. We report here that this is the case with brain-derived neurotrophic factor, a protein of extremely low abundance purified from the central nervous system.     

Expression of human proteoglycan in Chinese hamster ovary cells inhibits cell proliferation

In studying the functional role of an extracellular matrix proteoglycan, decorin, we have made observations that suggest a role for this proteoglycan in the control of cell proliferation. Extracellular matrices are made up of different combinations of collagens, elastin, hyaluronic acid, proteoglycans and various glycoproteins such as fibronectin. Most of these components can interact with cells, and much of the control of cell adhesion, migration and differentiation appears to be mediated by these interactions. Earlier studies have also attributed growth-regulatory activities to intact extracellular matrices, but the individual molecules responsible for these effects have not been characterized. We report here that Chinese hamster ovary (CHO) cell lines expressing human decorin from a stably transfected complementary DNA construct form a more orderly monolayer and grow to a lower saturation density than control cells lacking decorin. The extent of the morphological changes correlates with the level of decorin expression, and the saturation density is inversely proportional to it. The reduction in the saturation densities of the cell lines with the highest expression of decorin is more than 50%. These results reveal a novel growth inhibitory mechanism which may be related to contact inhibition of cell proliferation.     

核能谱与两类转动惯量的精确表达式

用最小二乘拟合法,将稀土区的能谱实验数据,拟合不同的能谱公式,从而证明E=a〔(1+bI(I+1))~(1/2)-1〕是符合得较好的,本文还推导了与上述能谱相应的两类转动惯量,并以此与实验计算值进行比较,结果仍很满意.