全文获取类型
收费全文 | 15295篇 |
免费 | 29篇 |
国内免费 | 47篇 |
专业分类
系统科学 | 63篇 |
丛书文集 | 181篇 |
教育与普及 | 33篇 |
理论与方法论 | 74篇 |
现状及发展 | 6255篇 |
研究方法 | 801篇 |
综合类 | 7679篇 |
自然研究 | 285篇 |
出版年
2013年 | 106篇 |
2012年 | 280篇 |
2011年 | 552篇 |
2010年 | 106篇 |
2008年 | 326篇 |
2007年 | 312篇 |
2006年 | 329篇 |
2005年 | 339篇 |
2004年 | 323篇 |
2003年 | 283篇 |
2002年 | 265篇 |
2001年 | 460篇 |
2000年 | 446篇 |
1999年 | 313篇 |
1992年 | 267篇 |
1991年 | 198篇 |
1990年 | 224篇 |
1989年 | 219篇 |
1988年 | 224篇 |
1987年 | 219篇 |
1986年 | 207篇 |
1985年 | 294篇 |
1984年 | 229篇 |
1983年 | 159篇 |
1982年 | 167篇 |
1981年 | 152篇 |
1980年 | 186篇 |
1979年 | 420篇 |
1978年 | 315篇 |
1977年 | 311篇 |
1976年 | 291篇 |
1975年 | 328篇 |
1974年 | 386篇 |
1973年 | 366篇 |
1972年 | 383篇 |
1971年 | 439篇 |
1970年 | 551篇 |
1969年 | 467篇 |
1968年 | 472篇 |
1967年 | 435篇 |
1966年 | 388篇 |
1965年 | 286篇 |
1964年 | 91篇 |
1959年 | 170篇 |
1958年 | 298篇 |
1957年 | 199篇 |
1956年 | 185篇 |
1955年 | 150篇 |
1954年 | 185篇 |
1948年 | 138篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
G. Zamboni E. Perez P. L. Parmeggiani 《Cellular and molecular life sciences : CMLS》1982,38(10):1188-1189
Summary In rats adapted to a 1212 h light-dark (LD) schedule, cyclic AMP concentration in the preoptic region showed a L minimum and D maximum. No significant fluctuations were observed in the parietal cortex.Supported by grant No. 79.01946.04 awarded by the National Research Council (CNR), Rome, Italy. 相似文献
92.
Captopril (SQ 14,225): In vitro and in vivo influence on the proliferative response of rat lymphocytes 总被引:1,自引:0,他引:1
Lise Binderup E. Bramm E. Arrigoni-Martelli 《Cellular and molecular life sciences : CMLS》1982,38(3):399-401
Summary Captopril in vitro (50–500 g/ml) increased3H-TdR incorporation in unstimulated and mitogen-stimulated cultures of rat lymphocytes. Unseparated spleen and lymph node cells of rats orally treated with captopril (50 mg/kg/day×4) showed decreased basal and mitogen stimulated3H-TdR incorporation. The removal of macrophages abrogated this inhibitory effect. Leucine aminopeptidase activity of macrophages was reduced — in vivo and in vitro — by captopril.Acknowledgments. The authors thank the Squibb Institute for Medical Research for the gift of Captopril. The excellent technical assistance of Ms B. Hasselriis, Ms B. Rumler and Ms E. Greve Petersen is gratefully acknowledged. 相似文献
93.
Summary The defense secretion of soldiers ofReticulitermes lucifugus has been shown to contain, predominantly, (R)-(–)-(E,E)-geranyllinalool together with germacrene A and -farnesene.This report covers part of a collaborative study with J.-L. Clément, Lab. d'Evolution, Université P. et M. Curie, Paris, to whom we are grateful for supplies of material and discussions. We also thank Dr O.T. Jones for collections ofReticulitermes lucifugus. 相似文献
94.
Genetic polymorphisms and intrauterine development. Evidence of decreased heterozygosity in light-for-dates human newborn babies 总被引:2,自引:0,他引:2
E. Bottini F. Gloria-Bottini P. Lucarelli A. Polzonetti F. Santoro A. Varveri 《Cellular and molecular life sciences : CMLS》1979,35(12):1565-1567
Summary In 2 independent samples of low-birth-weight infants the proportion of females and homozygotes for a series of polymorphic systems was higher in light-for-dates than in preterm babies. The observation seems to give support to the hypothesis that homozygosity for normal polymorphisms may decrease in general intrauterine growth rate. Since it is known that survival rate is strongly related to birth weight, a correlation between growth retardation and homozygosity may have a major role in the maintenance of such polimorphisms.We thank Prof. L. Ginzburg for helpful comments. 相似文献
95.
C Radanyi G Redeuilh E Eigenmann M C Lebeau N Massol C Secco E E Baulieu H Richard-Foy 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1979,288(2):255-258
The antibodies against estrogen receptor were obtained after injecting Rabbits with a cytoplasmic receptor fraction isolated from Calf uterus. The estrogen receptor was partially proteolysed by the action of trypsin and subsequently purified by affinity chromatography (purification 4,000 to 10,000 fold, to a purity of 5-20%). The affinity of the antibody for the proteolysed receptor is KD approximately 1 nM and serum titres have reached values of approximately 50 nM. The values remained constant after the third injection. Preliminary results indicate that the antibody has approximately the same affinity for "native" cytoplasmic estrogen receptor from Calf uterus, as well as for the "trypsinized" forms of estrogen receptor isolated from Calf uterine cytosol and Hen oviduct nuclei. 相似文献
96.
S André N Farjaudon C Pareyre E Séguin 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1979,288(14):1095-1097
Comparing cytotoxicity of tubulosine and of six newly synthesized pseudo-tubulosines in the Allium test, we have characterized all the current features of protein inhibition. Nevertheless cytotoxicity of the six pseudotubulosines is much weaker. Furthermore, "floating poles anaphasis", a disturbance characteristic of the action of tubulosine, has been found with a lesser intensity with the other compounds. 相似文献
97.
B. Goldberg A. Stern J. Peisach W. E. Blumberg 《Cellular and molecular life sciences : CMLS》1979,35(4):488-489
Summary The low temperature EPR spectrum of a quickly reacted mixture of oxyhemoglobin and phenylhydrazine was studied. With the use of a computer, the spectral contribution of methemoglobin in the region of g=2 was subtracted. The remaining spectrum was that of an axial free radical (g=2.00, g=2.06) having the magnetic parameters of superoxide anion. In the presence of superoxide dismutase, this axial radical was not seen, confirming that superoxide anion is indeed generated by the reaction.The portion of this investigation carried out at the Albert Einstein College of Medicine was supported in part by US Public Health Service Research Grant HL-93399 from the Heart and Lung Institute and by National Institute Contract Nol-CP-55606 to J.P. This is communication No. 378 from the Joan and Lester Avnet Institute of Molecular Biology.Predoctoral fellow in the Medical Scientist Training Program (United States Public Health Service Grant 5-TO-5-GM 01669-12) at the New York University School of Medicine.Recipient of a grant-in-aid from the New York Heart Association. 相似文献
98.
E. Viggiani 《Cellular and molecular life sciences : CMLS》1979,35(9):1265-1266
Summary A method able to monitor transmitted light acoustically is described. It makes use of an amplifier of light variations, provided with a photocell and a sound device, a photometer, an optic probe and a special support.Acknowledgments. The author would like to thank Dr Leonard Salzarulo, chairman of the Physics Department of the New Jersey Institute of Technology, for the critical reading of the paper. The author acknowledges the invaluable assistance of Prof. Araldo Ramundo of the Centro Regionale Professionale in Cosenza, Italy, for designing and assembling the electronic amplifier. Appreciation is also extended to Prof. Giuseppe Battendieri of the Liceo Scientifico Enrico Fermi in Cosenza, Italy, for the schematic reproduction of the apparatus. 相似文献
99.
E. Ch. Herrmann 《Cellular and molecular life sciences : CMLS》1979,35(9):1263-1264
Summary The simple theoretical criterion for chemical carcinogenicity based on the average quasi-valence number is discussed and shown to be inappropriate as a reliable indicator of carcinogenicity of any organic compound.I thank very much Dr R. Gordon for reading the English text and also for a stimulating discussion. 相似文献
100.