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排序方式: 共有2335条查询结果,搜索用时 31 毫秒
961.
应用动态大系统模型解耦方法和分割求解法,将大型水电站仿真培训系统的教学模型分解成若干个独立运算的子系统,大大减少了每一时步的计算时间,并将该方法应用到一水电站仿真培训系统。 相似文献
962.
Combinatorial microRNA target predictions 总被引:59,自引:0,他引:59
Krek A Grün D Poy MN Wolf R Rosenberg L Epstein EJ MacMenamin P da Piedade I Gunsalus KC Stoffel M Rajewsky N 《Nature genetics》2005,37(5):495-500
963.
A genome-wide survey of RAS transformation targets 总被引:28,自引:0,他引:28
Zuber J Tchernitsa OI Hinzmann B Schmitz AC Grips M Hellriegel M Sers C Rosenthal A Schäfer R 《Nature genetics》2000,24(2):144-152
964.
Regulation of flowering time by FVE, a retinoblastoma-associated protein 总被引:25,自引:0,他引:25
Ausín I Alonso-Blanco C Jarillo JA Ruiz-García L Martínez-Zapater JM 《Nature genetics》2004,36(2):162-166
965.
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease 总被引:112,自引:0,他引:112
Kim JH Auerbach JM Rodríguez-Gómez JA Velasco I Gavin D Lumelsky N Lee SH Nguyen J Sánchez-Pernaute R Bankiewicz K McKay R 《Nature》2002,418(6893):50-56
Parkinson's disease is a widespread condition caused by the loss of midbrain neurons that synthesize the neurotransmitter dopamine. Cells derived from the fetal midbrain can modify the course of the disease, but they are an inadequate source of dopamine-synthesizing neurons because their ability to generate these neurons is unstable. In contrast, embryonic stem (ES) cells proliferate extensively and can generate dopamine neurons. If ES cells are to become the basis for cell therapies, we must develop methods of enriching for the cell of interest and demonstrate that these cells show functions that will assist in treating the disease. Here we show that a highly enriched population of midbrain neural stem cells can be derived from mouse ES cells. The dopamine neurons generated by these stem cells show electrophysiological and behavioural properties expected of neurons from the midbrain. Our results encourage the use of ES cells in cell-replacement therapy for Parkinson's disease. 相似文献
966.
Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo 总被引:2,自引:0,他引:2
Rouget C Papin C Boureux A Meunier AC Franco B Robine N Lai EC Pelisson A Simonelig M 《Nature》2010,467(7319):1128-1132
967.
Isolation of an autotrophic ammonia-oxidizing marine archaeon 总被引:44,自引:0,他引:44
For years, microbiologists characterized the Archaea as obligate extremophiles that thrive in environments too harsh for other organisms. The limited physiological diversity among cultivated Archaea suggested that these organisms were metabolically constrained to a few environmental niches. For instance, all Crenarchaeota that are currently cultivated are sulphur-metabolizing thermophiles. However, landmark studies using cultivation-independent methods uncovered vast numbers of Crenarchaeota in cold oxic ocean waters. Subsequent molecular surveys demonstrated the ubiquity of these low-temperature Crenarchaeota in aquatic and terrestrial environments. The numerical dominance of marine Crenarchaeota--estimated at 10(28) cells in the world's oceans--suggests that they have a major role in global biogeochemical cycles. Indeed, isotopic analyses of marine crenarchaeal lipids suggest that these planktonic Archaea fix inorganic carbon. Here we report the isolation of a marine crenarchaeote that grows chemolithoautotrophically by aerobically oxidizing ammonia to nitrite--the first observation of nitrification in the Archaea. The autotrophic metabolism of this isolate, and its close phylogenetic relationship to environmental marine crenarchaeal sequences, suggests that nitrifying marine Crenarchaeota may be important to global carbon and nitrogen cycles. 相似文献
968.
苏里格气田盒8段高分辨率层序结构特征 总被引:11,自引:3,他引:11
通过钻井岩芯观察,结合测井资料和地震解释成果,按基准面旋回原理,把鄂尔多斯盆地石盒子组第8段划分为一个超长旋回层序、两个长期、四个中期和若干短期基准面旋回层序,并深入分析了形成中期、短期层序结构类型(A,C型)的背景、层序结构特征及其与储集砂体的展布关系.研究表明:不同的层序结构类型的形成受控于沉积背景、构造活动等所决定的可容纳空间和A/S值的变化.为进一步研究盒8段乃至整个石盒子组高分辨率层序地层学特征奠定了基础. 相似文献
969.
Allocosa brasiliensis (Petrunkevitch, 1910) is a wolf spider that constructs silk-lined burrows along the coastal sand dunes of Argentina, Brazil and Uruguay. This species shows a reversal in typical sex roles and sexual size dimorphism expected for spiders. Females are the smaller and mobile sex, which initiates courtship at the male burrow entrance. Mating occurs in the male burrow, and when it ends, the male leaves and the female stays inside. Females prefer to mate with those males showing longest burrows, so burrow dimensions would be under strong sexual selection pressures. Previous studies in the laboratory indicated that male burrows are longer than those of virgin females, which were described as simple silk capsules. Preliminary observations suggested that juvenile burrows presented differences from those of adults; however, detailed observations of A. brasilienisis burrow characteristics at the field were lacking. The aim of this study was to characterise the burrows of adults and juveniles of A. brasiliensis under natural conditions. We recorded the dimensions of burrows inhabited by males, females and juveniles (n = 30 for each category) and created beeswax moulds that reflected burrow shape. Juveniles inhabited tubular burrows with two branches and two openings; on the contrary, adults were found in tubular burrows with a single entry. Males and females inhabited burrows of similar length and width, but those of juveniles were shorter and narrower. We discuss the results and their possible functional explanations according to the selective pressures expected for each developmental stage and sex. 相似文献
970.