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排序方式: 共有88条查询结果,搜索用时 15 毫秒
51.
52.
R Chany-Fournier M C Moreau M V Santos 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1976,282(22):2007-2010
V.S.V. induced polycaryocytes in rat embryonic fibroblasts, transformed by the Prague strain of Sarcoma Rous (XC cells). This fusion is strictly dependent on the expression of the viral genome and is probably due to the incorporation of viral antigens in the cell membrane. The integrity of cellular RNA synthesis is however not required. The fusion is probably due to a membrane structure characteristic of these transformed cells. 相似文献
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Initial sequencing and analysis of the human genome 总被引:11,自引:0,他引:11
Lander ES Linton LM Birren B Nusbaum C Zody MC Baldwin J Devon K Dewar K Doyle M FitzHugh W Funke R Gage D Harris K Heaford A Howland J Kann L Lehoczky J LeVine R McEwan P McKernan K Meldrim J Mesirov JP Miranda C Morris W Naylor J Raymond C Rosetti M Santos R Sheridan A Sougnez C Stange-Thomann N Stojanovic N Subramanian A Wyman D Rogers J Sulston J Ainscough R Beck S Bentley D Burton J Clee C Carter N Coulson A Deadman R Deloukas P Dunham A Dunham I Durbin R French L Grafham D Gregory S 《Nature》2001,409(6822):860-921
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence. 相似文献
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Thayanne Lima Barros Cinthya Simone Gomes Santos José Eriberto De Assis José Roberto Botelho de Souza 《Journal of Natural History》2017,51(19-20):1169-1181
Polydora websteri belongs to a group of the Spionidae known as the Polydora complex, members of which are known for building tubes within the shells of mussels and for their ability to infest commercially valuable bivalves, which causes serious losses for malacoculture. P. websteri is a species subjected to increasing research due to the global scale at which these infestations occur. In this paper, we describe the larval development of P.cf. websteri associated with the oyster Crassostrea cf. brasiliana in a tropical region of north-east Brazil. The main structures of all stages of development were analysed and compared to other populations of P. websteri. Ovigerous capsules of P.cf. websteri were cultured in the laboratory and the larval stages were analysed until metamorphosis. Ovigerous capsules were present in all sampling intervals, indicating that this population exhibits continuous reproduction. Up to 21 capsules per tube were found, and the number of eggs per capsule varied from 20 to 40. All observed eggs developed into larvae. Larval development from egg to recruitment stage did not exceed 13 days. Metamorphosis occurred when larvae attained 17 chaetigers, at which stage important diagnostic characteristics were revealed, such as the spines on chaetiger 5. The developmental stages of P.cf. websteri larvae, and the morphological features found at each stage, are in accordance with what has been recorded for temperate populations. In our study, the planktonic stage was found to be of shorter duration than elsewhere, which might be associated with the higher temperatures at which larvae were cultured compared to previous studies. 相似文献
57.
P. Souza Santos A. Vallejo-Freire J. Parsons J. H. L. Watson 《Cellular and molecular life sciences : CMLS》1958,14(9):318-320
Résumé Les auteurs démontrent que le gel d'hydroxyde d'aluminium (gel deSchmidt) soumis aux rayons X diffractés et examiné au microscope électronique se révèle formé de particules différant par leur structure, leur morphologie et leur dimensions de celles du gel C-gamma deWillstätter, mais semblables à celles du gel C-béta du même nom. 相似文献
58.
A. L. Ferreira J. C. M. Santos M. A. Rossi 《Cellular and molecular life sciences : CMLS》1975,31(1):82-83
Zusammenfassung Bei Ratten, die während 4 Monaten ad libitum 40% igen Zuckerrohrschnaps getrunken hatten, wurden tiefgreifende Degenerationserscheinungen des adrenergischen Nervenplexus der Atrioventrikularklappen festgestellt.
At the time of this investigation J.C.M.S. was holder of a fellowship of the Conselho Nacional de Pesquisas. 相似文献
At the time of this investigation J.C.M.S. was holder of a fellowship of the Conselho Nacional de Pesquisas. 相似文献
59.
J. P. Guimarães I. Ballini M. C. Santos Motta 《Cellular and molecular life sciences : CMLS》1963,19(4):199-201
Zusammenfassung Es wird über die Verbreitung des metastatischen Yoshida-Sarkoms bei Ratten berichtet, die das Sarkom in den Schwanz geimpft erhielten. Die geimpften Tiere wurden mit Testosteron, Cortison und Östrogen behandelt. Die einfache Einpflanzung des Sarkoms ist nicht genügend, um die Verbreitung der Geschwulst zu veranlassen. 相似文献
60.
Neuronal polarization occurs shortly after mitosis. In neurons differentiating in vitro, axon formation follows the segregation of growth-promoting activities to only one of the multiple neurites that form after mitosis. It is unresolved whether such spatial restriction makes use of an intrinsic program, like during C. elegans embryo polarization, or is extrinsic and cue-mediated, as in migratory cells. Here we show that in hippocampal neurons in vitro, the axon consistently arises from the neurite that develops first after mitosis. Centrosomes, the Golgi apparatus and endosomes cluster together close to the area where the first neurite will form, which is in turn opposite from the plane of the last mitotic division. We show that the polarized activities of these organelles are necessary and sufficient for neuronal polarization: (1) polarized microtubule polymerization and membrane transport precedes first neurite formation, (2) neurons with more than one centrosome sprout more than one axon and (3) suppression of centrosome-mediated functions precludes polarization. We conclude that asymmetric centrosome-mediated dynamics in the early post-mitotic stage instruct neuronal polarity, implying that pre-mitotic mechanisms with a role in division orientation may in turn participate in this event. 相似文献