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71.
Sinkins SP Walker T Lynd AR Steven AR Makepeace BL Godfray HC Parkhill J 《Nature》2005,436(7048):257-260
Wolbachia is a common maternally inherited bacterial symbiont able to induce crossing sterilities known as cytoplasmic incompatibility (CI) in insects. Wolbachia-modified sperm are unable to complete fertilization of uninfected ova, but a rescue function allows infected eggs to develop normally. By providing a reproductive advantage to infected females, Wolbachia can rapidly invade uninfected populations, and this could provide a mechanism for driving transgenes through pest populations. CI can also occur between Wolbachia-infected populations and is usually associated with the presence of different Wolbachia strains. In the Culex pipiens mosquito group (including the filariasis vector C. quinquefasciatus) a very unusual degree of complexity of Wolbachia-induced crossing-types has been reported, with partial or complete CI that can be unidirectional or bidirectional, yet no Wolbachia strain variation was found. Here we show variation between incompatible Culex strains in two Wolbachia ankyrin repeat-encoding genes associated with a prophage region, one of which is sex-specifically expressed in some strains, and also a direct effect of the host nuclear genome on CI rescue. 相似文献
72.
Degassing of the Earth's mantle through magmatism results in the irreversible loss of helium to space, and high (3)He/(4)He ratios observed in oceanic basalts have been considered the main evidence for a 'primordial' undegassed deep mantle reservoir. Here we present a new global data compilation of ocean island basalts, representing upwelling 'plumes' from the deep mantle, and show that island groups with the highest primordial signal (high (3)He/(4)He ratios) have striking chemical and isotopic similarities to mid-ocean-ridge basalts. We interpret this as indicating a common history of mantle trace element depletion through magmatism. The high (3)He/(4)He in plumes may thus reflect incomplete degassing of the deep Earth during continent and ocean crust formation. We infer that differences between plumes and the upper-mantle source of ocean-ridge basalts reflect isolation of plume sources from the convecting mantle for approximately 1-2 Gyr. An undegassed, primordial reservoir in the mantle would therefore not be required, thus reconciling a long-standing contradiction in mantle dynamics. 相似文献
73.
The Amazon basin in transition 总被引:7,自引:0,他引:7
Davidson EA de Araújo AC Artaxo P Balch JK Brown IF C Bustamante MM Coe MT DeFries RS Keller M Longo M Munger JW Schroeder W Soares-Filho BS Souza CM Wofsy SC 《Nature》2012,481(7381):321-328
Agricultural expansion and climate variability have become important agents of disturbance in the Amazon basin. Recent studies have demonstrated considerable resilience of Amazonian forests to moderate annual drought, but they also show that interactions between deforestation, fire and drought potentially lead to losses of carbon storage and changes in regional precipitation patterns and river discharge. Although the basin-wide impacts of land use and drought may not yet surpass the magnitude of natural variability of hydrologic and biogeochemical cycles, there are some signs of a transition to a disturbance-dominated regime. These signs include changing energy and water cycles in the southern and eastern portions of the Amazon basin. 相似文献
74.
Two decades of scientific ocean drilling have demonstrated widespread microbial life in deep sub-seafloor sediment, and surprisingly high microbial-cell numbers. Despite the ubiquity of life in the deep biosphere, the large community sizes and the low energy fluxes in this vast buried ecosystem are not yet understood. It is not known whether organisms of the deep biosphere are specifically adapted to extremely low energy fluxes or whether most of the observed cells are in a dormant, spore-like state. Here we apply a new approach--the D:L-amino-acid model--to quantify the distributions and turnover times of living microbial biomass, endospores and microbial necromass, as well as to determine their role in the sub-seafloor carbon budget. The approach combines sensitive analyses of unique bacterial markers (muramic acid and D-amino acids) and the bacterial endospore marker, dipicolinic acid, with racemization dynamics of stereo-isomeric amino acids. Endospores are as abundant as vegetative cells and microbial activity is extremely low, leading to microbial biomass turnover times of hundreds to thousands of years. We infer from model calculations that biomass production is sustained by organic carbon deposited from the surface photosynthetic world millions of years ago and that microbial necromass is recycled over timescales of hundreds of thousands of years. 相似文献
75.
J Pross L Contreras PK Bijl DR Greenwood SM Bohaty S Schouten JA Bendle U Röhl L Tauxe JI Raine CE Huck T van de Flierdt SS Jamieson CE Stickley B van de Schootbrugge C Escutia H Brinkhuis;Integrated Ocean Drilling Program Expedition Scientists 《Nature》2012,488(7409):73-77
The warmest global climates of the past 65 million years occurred during the early Eocene epoch (about 55 to 48 million years ago), when the Equator-to-pole temperature gradients were much smaller than today and atmospheric carbon dioxide levels were in excess of one thousand parts per million by volume. Recently the early Eocene has received considerable interest because it may provide insight into the response of Earth's climate and biosphere to the high atmospheric carbon dioxide levels that are expected in the near future as a consequence of unabated anthropogenic carbon emissions. Climatic conditions of the early Eocene 'greenhouse world', however, are poorly constrained in critical regions, particularly Antarctica. Here we present a well-dated record of early Eocene climate on Antarctica from an ocean sediment core recovered off the Wilkes Land coast of East Antarctica. The information from biotic climate proxies (pollen and spores) and independent organic geochemical climate proxies (indices based on branched tetraether lipids) yields quantitative, seasonal temperature reconstructions for the early Eocene greenhouse world on Antarctica. We show that the climate in lowland settings along the Wilkes Land coast (at a palaeolatitude of about 70° south) supported the growth of highly diverse, near-tropical forests characterized by mesothermal to megathermal floral elements including palms and Bombacoideae. Notably, winters were extremely mild (warmer than 10?°C) and essentially frost-free despite polar darkness, which provides a critical new constraint for the validation of climate models and for understanding the response of high-latitude terrestrial ecosystems to increased carbon dioxide forcing. 相似文献
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78.
Iverson RM Dzurisin D Gardner CA Gerlach TM LaHusen RG Lisowski M Major JJ Malone SD Messerich JA Moran SC Pallister JS Qamar AI Schilling SP Vallance JW 《Nature》2006,444(7118):439-443
The 2004-05 eruption of Mount St Helens exhibited sustained, near-equilibrium behaviour characterized by relatively steady extrusion of a solid dacite plug and nearly periodic shallow earthquakes. Here we present a diverse data set to support our hypothesis that these earthquakes resulted from stick-slip motion along the margins of the plug as it was forced incrementally upwards by ascending, solidifying, gas-poor magma. We formalize this hypothesis with a dynamical model that reveals a strong analogy between behaviour of the magma-plug system and that of a variably damped oscillator. Modelled stick-slip oscillations have properties that help constrain the balance of forces governing the earthquakes and eruption, and they imply that magma pressure never deviated much from the steady equilibrium pressure. We infer that the volcano was probably poised in a near-eruptive equilibrium state long before the onset of the 2004-05 eruption. 相似文献
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80.
Pike-Overzet K de Ridder D Weerkamp F Baert MR Verstegen MM Brugman MH Howe SJ Reinders MJ Thrasher AJ Wagemaker G van Dongen JJ Staal FJ 《Nature》2006,443(7109):E5; discussion E6-E5; discussion E7
The gene IL2RG encodes the gamma-chain of the interleukin-2 receptor and is mutated in patients with X-linked severe combined immune deficiency (X-SCID). Woods et al. report the development of thymus tumours in a mouse model of X-SCID after correction by lentiviral overexpression of IL2RG and claim that these were caused by IL2RG itself. Here we find that retroviral overexpression of IL2RG in human CD34+ cells has no effect on T-cell development, whereas overexpression of the T-cell acute lymphoblastic leukaemia (T-ALL) oncogene LMO2 leads to severe abnormalities. Retroviral expression of IL2RG may therefore not be directly oncogenic--rather, the restoration of normal signalling by the interleukin-7 receptor to X-SCID precursor cells allows progression of T-cell development to stages that are permissive for the pro-leukaemic effects of ectopic LMO2. 相似文献