海马MF-CA3突触习得性LTP诱导后PPF效应的变化

采用电生理学与行为学结合的方法，通过慢性微电极埋植技术及双脉冲检测技术，观察大鼠海马MF-CA3突触在明暗辨别学习过程中形成习得性长时程增强（Long-term potentiation, LTP）后双脉冲易化（Paired-pulse facilitation, PPF）效应的变化. 结果表明:Mossy fibers-CA3（MF-CA3）突触习得性LTP形成前的PPF易化率为138.36%9.25%，形成后则为114.75%8.42%，差异极显著（p 0.01），而基线对照组在长达7天的检测中，PPF易化率稳定在140%左右. 研究结果显示，MF-CA3突触的习得性LTP的表达可能与突触前递质释放的改变有关.     

从电影片名翻译看其静动转化及策略

多年的英汉对比研究表明，英语表现为静态性语言，汉语则是动态性语言。本文通过列举近几十年来奥斯卡获奖英语电影片名的翻译和个别电影名称的几个译本，表现了英汉翻译中的“动静相宜”。同时提出在影片的翻译策略上，归化和异化相比较而言，归化对于目的语观众似乎更加具有感召力。     

基于用于推进的功率定量分析运输效率的发展趋势(英文)

基于Nakazawa教授提供的有关20世纪70年代到2008年相关船舶数据,对船舶特定输出功率(SOP)进行定量分析,探讨船舶运输效率的发展趋势和制约因素.     

New Voronoi Diagram Algorithm of Multiply-Connected Planar Areas in the Selective Laser Melting

This paper studies the practical generation of Voronoi diagrams for multiply-connected planar areas bounded by line segments. The core of the algorithm was calculating Voronoi polygon of every Voronoi object in planar areas independently. The main approach had two steps. The first step was calculating all relevant bisectors of every Voronoi object. The second was combining obtained bisectors into completed Voronoi polygons individually. All code was implemented in Visual C++ platform. The resulting code was extensively tested in real-world data and its practical running time grew only linearly. Three statistical CPU-consumption charts had been drawn with the Voronoi diagrams computation data, and compared with other published codes for computing Voronoi diagrams. The algorithm was applied to compute offsetting of slice area consisting of large-scale line segments for the selective laser melting (SLM) trajectory scanning technology which is a kind of rapid prototyping (RP). The experimental results of offsetting for slice area based on Voronoi diagrams show that the approach is effective and simple for polygon offsetting problems. The method is helpful to those offsetting work and can provide more effective offsetting solution.     

基本模型机仿真软件的设计与实现

基于TDN-CM++基本模型机的组成结构,利用JBuilder 9开发了一个仿真系统.该系统可以实现对模型机指令系统的仿真测试,实时、动态地显示各硬件组成部件的数据值,并以动画方式演示数据通路的建立过程.     

化学隔离抑爆系统在纺织行业的应用

介绍化学隔离抑爆系统的工作原理及其基本组成,以及典型的化学隔离抑爆系统产品,探讨在纺织行业化学隔离抑爆系统的安装位置。指出设备安装化学隔离抑爆系统后,不仅可预防和抑制其爆炸的发生,而且可以降低对其强度的要求,从而节省设备的经济投入。最后,为更全面更安全的保护过程设备,建议化学隔离抑爆系统应与更多的保护方案组合使用。     

南渡江水源水光催化灭菌实验研究

为了研究二氧化钛光催化对自来水和水源水灭菌性能,以二氧化钛薄膜为催化剂,在紫外灯和太阳光照射后分别考察灭菌效果,结果表明在4w低压汞灯和太阳光照射下,对自来水和水源水有很好的灭菌作用.光催化灭菌效果明显优于空白实验.单纯采用太阳光照射的水样,细菌不但去除不完全,而且存在复活现象.     

Prediction of sites under adaptive evolution in flavin-containing monooxygenases: Selection pattern revisited

Flavin-containing monooxygenase (FMO), like cytochrome P450 (CYP), is a monooxygenase that uses the reducing equivalents of NADPH to reduce one atom of molecular oxygen to water, while the other atom is used to oxidize the substrate. Recently, it was shown that some CYP isoforms have been subject to positive selection. However, it is unknown whether the highly conserved phase I detoxification enzyme, FMO, has undergone similar positive Darwinian selection. We used maximum-likelihood models of codon substitution, evolutionary fingerprinting, and cross species comparison to investigate the occurrence of adaptive evolution in FMO sequences. We used recent genomic data from a range of species, including vertebrates and invertebrates. We present the evidence for the occurrence of adaptive evolution in mammalian FMO 3, 4, 5, and fugu FMOs but not in mammalian FMO 1, FMO 2, frog FMOs, other fish FMOs and invertebrate FMOs. The sites under adaptive evolution were significantly associated with the insertion domain in mammalian FMO 5. We identified specific amino acid sites in FMOs 3–5 that are likely targets for selection based on the patterns of parallel amino acid change. The most likely role of adaptive evolution is the repair of mutations that permitted optimal NADP+ binding and improved catalytic efficiency. The occurrence of positive selection during the evolution of phase I detoxification enzymes such as FMOs 3–5 and fugu FMO suggests the occurrence of both high selection pressure acting on species within their unique habitats and significant changes in intensity and direction (forms of xenobiotics and drugs) resulting from changes in microhabitat and food.     

如何从局部到整体解决一次高频通道的长期缺陷

腰鼓湾站自2009年投运以来,唐腰线(唐美站至腰鼓湾站)高频通道一直出现异常情况,之间经过多次的处理。文章通过处理该缺陷,既从局部来解决问题,又整体地对问题综合分析处理,研究了消除该通道的故障的措施。     

信息环境下图书馆员继续教育研究

随着网络信息技术的高速发展,图书馆的信息采集、组织、保存以及服务方式都发生了改变,用户利用信息的习惯也得到改变。只有加强图书馆员的继续教育,才能提升图书馆的服务质量。在阐述图书馆员继续教育意义的基础上,结合国内外有关图书馆员继续教育的研究状况,探讨了图书馆员继续教育的途径。