高速磁浮曲线地段简支轨道梁墩体系动力响应仿真

应用桥梁动力学、车辆动力学和电磁相互作用原理建立了高速常导磁浮交通车-梁-墩体系动力分析模型,利用数值积分求解了大规模非线性耦合动力方程.在此基础上结合具体线路条件进行了车线耦合动力学检算,得到了曲线地段车辆及梁墩体系动力响应基本规律.该部分的研究为制订合理的高速磁浮线路设计标准提供了理论依据.     

加配重复摆振动周期的变化规律

通过理论推导、研究和分析，得出了加配重复摆振动周期的变化规律．     

低压电力线通信的应用

综述了低压电力线通信(Power Line Communication,PLC)的技术特点、有关技术标准以及其产品和市场应用的情况,以使读者全面了解其发展现状;介绍了其作为接入网的应用框架,给出了小区(包括底层住宅、高层住宅和商用写字楼)低压PLC接入网的典型解决方案,以供有相关组网需求的读者参考.通过对比其他接入网方式,表明低压PLC具有覆盖面广、成本低廉、带宽较宽和安装容易的优点.结论是,低压PLC的应用必将越来越广泛.     

改进Copula对数据拟合的方法

给出相关结构Copula、秩相关系数Spearmanρ与Kendallτ和尾部相关系数η,以及这三个关联性度量与Copula之间的关系,各个相关系数的估计方法.在一个Copula族内进行适当变换,得到新的Copula,使得能更好地拟合样本的各个相关系数.最后,以沪、深日收盘综合指数为例,讨论了二个股市波动率的相关性,建立了一个较好的数学模型.     

基于3S技术的土地利用动态变化研究

3S技术是进行资源环境研究的重要技术手段,在土地利用动态变化研究中,应用3S技术能够快速地获取动态变化信息,并进行空间叠加分析,具有传统方法无可比拟的优越性。该文以北京市密云县为例,探讨了基于3S技术的土地利用动态变化研究方法;并在3S技术支持下,对密云县1991年到2001年的土地利用状况进行了定量的变化分析。结果表明:从1991年到2001年,密云县土地利用变化呈现出下列特点——林地面积持续增加,耕地面积不断减少,密云水库面积明显减少,形势比较严峻。     

Quantal transmitter secretion from myocytes loaded with acetylcholine.

It is well known that transmitter secretion requires specialized secretory organelles, the synaptic vesicles, for the packaging, storage and exocytotic release of the transmitter. Here we report that when acetylcholine (ACh) is loaded into an isolated Xenopus myocyte, there is spontaneous quantal release of ACh from the myocyte which results in activation of its own surface ACh channels and the appearance of membrane currents resembling miniature endplate currents. This myocyte secretion probably reflects Ca(2+)-regulated exocytosis of ACh-filled cytoplasmic compartments. Furthermore, step depolarization of the myocyte membrane triggers evoked ACh release from the myocyte with a weak excitation-secretion coupling. These findings suggest that quantal transmitter secretion does not require secretory pathways unique to neurons and that the essence of presynaptic differentiation may reside in the provision of transmitter supply and modification of the preexisting secretion pathway.     

新型全固态铁离子敏感电极研究

采用稀土电极材料六硼化镧制备了一种新的全固态铁离子敏感电极。研究了该敏感电极在常见介质中对Ｆｅ３＋的响应行为。结果表明，该铁离子敏感电极在１．５ｍｏｌ／ＬＨ３ＰＯ４介质中的线性响应范围、检测下限和响应斜率分别为１．０×１０－５～１．０×１０－１ｍｏｌ／ＬＦｅ３＋，６．０×１０－６ｍｏｌ／ＬＦｅ３＋和６０ｍＶ／ｐＣ，且具有较好的选择性。     

A calcium sensor in the sodium channel modulates cardiac excitability.

Sodium channels are principal molecular determinants responsible for myocardial conduction and maintenance of the cardiac rhythm. Calcium ions (Ca2+) have a fundamental role in the coupling of cardiac myocyte excitation and contraction, yet mechanisms whereby intracellular Ca2+ may directly modulate Na channel function have yet to be identified. Here we show that calmodulin (CaM), a ubiquitous Ca2+-sensing protein, binds to the carboxy-terminal 'IQ' domain of the human cardiac Na channel (hH1) in a Ca2+-dependent manner. This binding interaction significantly enhances slow inactivation-a channel-gating process linked to life-threatening idiopathic ventricular arrhythmias. Mutations targeted to the IQ domain disrupted CaM binding and eliminated Ca2+/CaM-dependent slow inactivation, whereas the gating effects of Ca2+/CaM were restored by intracellular application of a peptide modelled after the IQ domain. A naturally occurring mutation (A1924T) in the IQ domain altered hH1 function in a manner characteristic of the Brugada arrhythmia syndrome, but at the same time inhibited slow inactivation induced by Ca2+/CaM, yielding a clinically benign (arrhythmia free) phenotype.     

类DLVO理论与胆固醇单水结晶形成过程

就人体胆汁胆固醇单水结晶形成过程提出了类DLVO理论,应用该理论初步阐明了其结晶过程可能的化学物理机制,并分析了该理论在促、抗成核因子及溶石方面的意义.     

毕竟正则半群上的群同余

设S是一个半群,a∈S.如果存在x∈S,使得x=xax,则称x为a的一个弱逆.用W(a)表示a的所有弱逆的集合.本文利用元素的弱逆给出了毕竟正则半群S的群同余的若干等价刻画及一个表示.通过S的w-自共轭的、闭的,全子半群H定义了S上的一个二元关系(a,b)∈ρH( )(( )a'∈W(a),a'b∈H),证明了如果H是S的w-自共轭的、闭的全子半群,则ρH是S上的以H为核的群同余.反过来,如果ρ是S上的群同余,则kerρ是S的w-自共轭的,闭的全子半群,并且ρ=ρker ρ.