Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system

Using a prokaryote (Escherichia coli) and a metazoa-resembling eukaryote (Ochromonas danica), we surveyed antioxidants which might overcome redox stress imposed by menadione sodium bisulphite (MD) and buthionine sulphoximine (BSO). BSO oxidant stress was evident only inO. danica; MD oxidant stress was evident in both organisms. Glutathione, its precursors, e.g. cysteine, homocysteine, and 2-oxo-4-thiazolidine carboxylic acid, and red blood cells, emerged as prime antioxidants for relieving BSO and MD oxidant stress. BSO and MD oxidant activity and antioxidant-annulling effect inO. danica were judged comparable to those found in animal cells whereas the resultsE. coli were not entirely equivalent. TheO. danica system emerged as a practical, rapid, and useful system for pinpointing oxidant stressors and antioxidants, and shows promise for studies with mammalian systems.     

(−)-Epigallocatechin gallate,a polyphenolic tea antioxidant,inhibits peroxynitritemediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine

Reaction with peroxynitrite at pH 7.4 and 37°C was found to increase the 8-oxodeoxyguanosine levels in calf thymus DNA 35-38-fold. This oxidation of deoxyguanosine, as well as the peroxynitrite-mediated nitration of tyrosine to 3-nitrotyrosine, was significantly inhibited by ascorbic acid, glutathione and (–)-epigallocatechin gallate, a polyphenolic antioxidant present in tea. For 50% inhibition of the oxidation of deoxyguanosine to 8-oxodeoxyguanosine, 1.1, 7.6 of 0.25 mM ascorbate, glutathione or (–)-epigallocatechin gallate, respectively, was required. For 50% inhibition of tyrosine nitration, the respective concentrations were 1.4, 4.6 or 0.11 mM. Thus, (–)-epigallocatechin gallate is a significantly better inhibitor of both reactions than either ascorbate or glutathione. Reaction of (–)-epigallocatechin gallate with peroxynitrite alone resulted in the formation of a number of products. Ultraviolet spectra of two of these suggest that the tea polyphenol and/or its oxidation products are nitrated by peroxynitrite.     

Global warming： Take action or wait？

Of all the changes wrought by human activity, the buildup in our atmosphere of the greenhouse gases, carbon dioxide, methane and nitrous oxide, has gener- ated the most contentious debate. Environmentalists warn that in the absence of firm action, over th…     

矿石与材料发光光谱学

本书属于矿物物理领域，重点是矿物的发光光谱。本书使用的实验手段主要是激光激发矿物质和对其发射和散射结果进行时间分辨的探测。全书共11章。第1章简介，介绍了主要科学术语的定义以及激光诱导时间分辨技术和稳态发光等内容；第2章理论背景，解释了激发能的吸收、辐射跃迁等发光中的主要过程；第3章实验方法，描述了实验设备的主要部分;     

气体水合物研究进展

本书是2003年春季美国化学工程协会召开的“气体水合物讨论会”的论文集，共收录16篇论文。气体水合物是一种非常特殊的化学组成，它是由水分子（主体分子）包裹着气体分子（客体分子）在低温高压条件下形成的一种无化学键的晶体物质。通常的气体水合物是甲烷水合物，在常温常压下，甲烷水合物中包含的甲烷气体是甲烷水化物本身的180倍。作为一种替补能源，气体水合物的研究已经越来越受到人们的重视。     

城市交通发展

本书是关于城市交通管理的一本论文集，是根据2003年在瑞典召开的“未来城市交通：如何应对城市交通发展的复杂性”学术会议上宣读的论文编著而成。这次会议是由沃尔沃研究教育基金资助。本书阐述了多个城市交通的特点、复杂性的概念、如何应对复杂性、汽车交通系统的作用。并对亚洲、非洲、欧洲等多国的交通系统模型做出了分析，提出了解决交通问题的一些措施。     

Depositional environments of Bathonian sediments from the Jaisalmer Basin, Rajasthan, western India

The pericratonic sedimentary Jaisalmer Basin, west of the Aravalli Ranges, on the westerly dipping eastern flank of the Indus Shelf, is a principal structural element of Rajasthan. Jurassic sediments in the SE comprise non-marine sandstones and conglomerates to nearshore, brackish to marine sands, silts, clays and carbonates, grouped lithostratigraphically into the Lathi, Jaisalmer, Baisakhi, and Bhadasar formations. The Late Bajocian to Oxfordian Jaisalmer Formation is divided, in ascending order, into the Hamira, Joyan, Fort, Badabag, Kuldhar, and Jajiya members. Fossil records providing a Bajocian to Bathonian age for the lower and middle parts of the formation include: a Late Bajocian coral Isastraea bernardiana (d’Orbigny) in the uppermost Joyan Member; Bathonian ammonite Clydoniceras in the basal part of the Badabag Member; Bathonian foraminiferal/bivalve assemblages in the Fort Member. The topmost bed of the Joyan Member represents the peak of first marine transgression of the Jaisalmer Basin, probably contemporaneous with the Late Bajocian one in the neighbouring Kachchh Basin. Based on faunal studies Bajocian to Bathonian sediments of the Jaisalmer Basin can be broadly correlated with those of the Kachchh Basin. The Fort and Badabag members represent the following depositional environments, in chronological order: (a) brackish to shallow fully marine; (b) fully marine with rapidly fluctuating water energy and sedimentation rates; (c) near-shore to lower shoreface with fluctuating energy conditions, salinity and sedimentation rates; (d) near-shore to shoreface channels and storm-dominated marine above fair-weather wave-base; (e) lagoon with fluctuating low to moderate energy, salinity and sedimentation rates; (f) stormdominated shelf to lower shoreface.     

中西方管理文化比较分析

阐述了企业管理文化概念以及中西方管理文化的形成及其差异，通过中西方管理文化差异形成原因的分析，指出了社会上普遍存在的“中国企业的出路就是按照西方管理来运作”的认识的不合理性，得出“中国管理文化并不会被西方管理文化所取代”的结论，并借助海尔企业文化案例，提出了中国企业文化的发展方向。     

山西省水资源可持续开发利用问题浅析

在对山西省水资源开发利用所面临的问题进行剖析的基础上。提出了合理开发地下水资源、拉制水资源污染、发展节水工程和实行水资源的统一管理等科学、合理开发利用水资源的对策。     

红豆杉细胞培养生产紫杉醇的研究进展

综述了近年来红豆杉细胞培养生产紫杉醇的研究进展, 包括红豆杉细胞培养生产紫杉醇的代谢调节、无机盐、植物生长调节因子、糖分及其它因素对红豆杉细胞生长和紫杉醇生产的影响等.着重介绍了前体饲喂、添加抑制剂和添加诱导子对红豆杉细胞生长及紫杉醇生产的影响.