8098远程通信的实现

单片机应用系统中经常要用到远距离串行通信,本文指出了一种单片机系统远距离串行通信的方法并在实际中应用.采用此方法,远距离通信媒介仅需一条双绞线,经济简单.通信距离可达几公里,且传输速率快,误码率低.     

蜜枣太阳能对流干燥最佳工况的研究

太阳能干燥技术的应用近十年来虽有较大的发展,但多数太阳能干燥器在工业生产中不能持久地应用而被闲置,以致太阳能干燥技术的推广应用未能持续发展,其主要原因是由于至今尚未有太阳能干燥的优化理论的指导,太阳能干燥过程不能优化调控,节能效果不明显。本文以蜜枣为干燥对象进行了太阳能对流干燥情况下的模拟测定,在试验的基础上建立了蜜枣的干燥数学模型,根据此模型以能耗为优化目标求得了蜜枣太阳能对流干燥时的最佳工况,可用于指导蜜枣的实际生产。     

科技期刊在科技成果转化方面的作用

结合自身办刊经验,说明科技期刊在科技成果转化中可以发挥重要作用并可提供多方位的信息服务。     

基于分级规划的加工方法排序规则研究

结合工艺决策的分级规划策略,构造了一种新的实用化的加工方法排序规则,该排序规则将传统排序规则分解成两个相关的部分：工序排序规则与工步排序规则．工序排序规则代表了排序规则的普遍性,描述了一类零件的总体加工过程,只与加工方法有关,与组成零件的形状特征等其他因素无关;工步排序规则代表了排序规则的特殊性,描述了工序中各特征的加工顺序,与特征有关而与加工方法无关．     

腐蚀管线剩余强度的非线性分析

应用计算机辅助工程分析系统,对腐蚀管线的剩余强度进行了有限元分析,分析中考虑了材料非线性和几何非线性。得出了腐蚀区的应力分布及腐蚀区应力随载荷变化的历程曲线,以及腐蚀区尺寸对剩余强度的影响,并对模型的失效压力进行了预测。将预测结果与工业上使用最广泛的Ｂ３１Ｇ准则预测的结果进行了比较,证明用此方法对腐蚀管线的剩余强度进行评估是可行的,能得到比较准确的结果。     

基于颗粒阻尼的超结构在管状带式输送机中的应用

为了减少管状带式输送机启机后产生的振动所带来的不利影响,现设计一种颗粒阻尼型声子晶体板。通过有限元法对声子晶体带隙成因进行研究,并对颗粒阻尼型声子晶体板进行建模。利用COMSOL得到颗粒阻尼型声子晶体的能带与传递损失图形,并对非颗粒阻尼型声子晶体与颗粒阻尼型声子晶体进行传递损失分析。实验结果表明,颗粒型声子晶体减振效果达到70.43%,相比非颗粒型声子晶体增加37.42%。研究结果为颗粒阻尼型声子晶体在管带机上的减振应用提供理论支撑。     

Generalized ridge estimation of a semiparametric regression model

We considered the following semiparametric regres-sion model yi = X iT β+ s ( t i ) + ei (i =1,2,,n). First,the general-ized ridge estimators of both parameters and non-parameters are given without a restrained design matrix. Second,the generalized ridge estimator will be compared with the penalized least squares estimator under a mean squares error,and some conditions in which the former excels the latter are given. Finally,the validity and feasibility of the method is illustrated by a simulation example.     

试论现代青花艺术的时代性

现代青花艺术是对传统青花艺术的延续和发展,是在继承传统青花艺术的基础上进行了取舍,融会了现代人的审美理念、创作思想及表现方法,体现新时代特征的青花艺术作品。时代不断发展,青花装饰也与时俱进,在继承传统的基础上,现代青花装饰向着多元化、自由化、个性化的方向发展,在现代青花艺术的各个方面都有充分的体现。     

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The gene encoding TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity (CN-LOH) in patients with diverse myeloid malignancies. Somatic TET2 mutations are frequently observed in myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), MDS/MPN overlap syndromes including chronic myelomonocytic leukaemia (CMML), acute myeloid leukaemias (AML) and secondary AML (sAML). We show here that TET2 mutations associated with myeloid malignancies compromise catalytic activity. Bone marrow samples from patients with TET2 mutations displayed uniformly low levels of 5hmC in genomic DNA compared to bone marrow samples from healthy controls. Moreover, small hairpin RNA (shRNA)-mediated depletion of Tet2 in mouse haematopoietic precursors skewed their differentiation towards monocyte/macrophage lineages in culture. There was no significant difference in DNA methylation between bone marrow samples from patients with high 5hmC versus healthy controls, but samples from patients with low 5hmC showed hypomethylation relative to controls at the majority of differentially methylated CpG sites. Our results demonstrate that Tet2 is important for normal myelopoiesis, and suggest that disruption of TET2 enzymatic activity favours myeloid tumorigenesis. Measurement of 5hmC levels in myeloid malignancies may prove valuable as a diagnostic and prognostic tool, to tailor therapies and assess responses to anticancer drugs.