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The DNP fibres gamma-irradiated under aerobic condition showed a reduction of their diameter, while no remarkable changes were observed in the DNP fibres irradiated under hypoxic condition by scanning electron microscopy. 相似文献
235.
Summary A new fluorescent -blocker, 9-amino-acridin propranolol (9-AAP), was administered i.v. to rats. Multiple fluorescent 9-AAP binding sites were observed on cardiac muscle cells in frozen sections. Intensity and density of cardiac 9-AAP fluorescence were markedly reduced following pretreatment with (±)- and (–)-propranolol but not with (+)-propranolol. Our findings suggest that 9-AAP may label -adrenergic receptor sites in rat myocardium.D. A. is supported by a fellowship from the Lady Davis Fellowship Trust and by a Research Grant from the Bat-Sheva de Rothschild Fund for The Advancement of Science and Technology. The technical assistance ofA. Itzhak is gratefully acknowledged. 相似文献
236.
V. R. Osório E Castro M. G. P. Vale A. P. Carvalho 《Cellular and molecular life sciences : CMLS》1976,32(4):424-426
Summary The effect of the antibiotic X-537A on the phosphorylated ATPase (EP) was investigated. The results show that X-537A depresses the level of EP which is dependent on the Ca2+ gradient, while the Ca2+-independent EP is not affected.
Acknowledgments. This work was supported by grants from the Instituto de Alta Cultura of the Portuguese Ministry of Education (No. CB/2) and the Calouste Gulbenkian Foundation. 相似文献
237.
G. M. Hanozet M. Simonetta D. Barisio A. Guerritore 《Cellular and molecular life sciences : CMLS》1976,32(10):1246-1249
Summary The three enzymes of ethanol metabolism alcohol dehydrogenase, aldehyde dehydrogenase and acetyl-CoA synthetase in the obligate aerobic yeastRhodotorula gracilis are repressed by glucose and induced by C2 metabolic fuels with a regulatory pattern indicating a correlation in the control mechanisms. To try an identification of the molecular signals involved in the transmission of the inducing stimulus, experiments were carried out by blocking with 2 mM pyrazole the ethanol acetaldehyde metabolic step. Results indicate that ethanol is not specifically required as a molecular signal for induction.This work was supported by a grant from the Italian Consiglio Nazionale delle Ricerche. 相似文献
238.
Summary Adenylate kinase activity of intact mitochondria is strongly inhibited by Ap5A, i.e.p
1,p
5-Di (adenosine-5-) pentaphosphate, whereas oxidative phosphorylation is not affected. Therefore, Ap5A is a useful tool to distinguish between oxidative and non oxidative ATP generating reactions.Acknowledgment. The generous support of Prof. Dr.Walther Lamprecht is gratefully acknowledged. J. L. thanks the Stipendienfonds des Verbandes der Chemische Industrie for a scholarship. 相似文献
239.
Summary Tryptic treatment of muscle thick filaments reveals the underlying backbones of aggregatedl-meromyosin as a coli of 3 secondary filaments (helical repeat 130 nm) each in turn a coli of a 3 finer ones. 相似文献
240.
Summary Rat brain mitochondria contain a significant proportion of poly(A) associated RNA which is higher than that found in microsomes from the same source. When steady state poly(A) RNA of brain mitochondria was analyzed by microelectrophoresis, it displayed a characteristic separation pattern with a large amount of free poly(A). 相似文献